Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3081
  Reference Plasmid   MET0041_bin.7__k81_33456
  Reference Plasmid Size   32582
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0072081 DNJJBEHE_00025 28136 3 Skin 0.43 protein_coding missense_variant MODERATE 575A>G Lys192Arg
M0072082 DNJJBEHE_00025 28567 4 Skin 0.57 protein_coding synonymous_variant LOW 144T>C Ser48Ser
M0072083 DNJJBEHE_00025 28585 4 Skin 0.57 protein_coding synonymous_variant LOW 126A>C Gly42Gly
M0072084 DNJJBEHE_00026 28841 5 Skin 0.71 protein_coding missense_variant MODERATE 472C>A His158Asn
M0072085 DNJJBEHE_00026 28977 5 Skin 0.71 protein_coding synonymous_variant LOW 336A>T Val112Val
M0072086 DNJJBEHE_00026 29217 5 Skin 0.71 protein_coding missense_variant MODERATE 96A>G Ile32Met
M0072087 DNJJBEHE_00026 29286 4 Skin 0.57 protein_coding synonymous_variant LOW 27A>T Ala9Ala
M0072088 DNJJBEHE_00026 29296 4 Skin 0.57 protein_coding missense_variant MODERATE 17G>T Cys6Phe
M0072089 DNJJBEHE_00022 29316 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -3081T>C None
M0072090 DNJJBEHE_00022 29329 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -3094T>A None
M0072091 DNJJBEHE_00022 29381 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3146C>T None
M0072092 DNJJBEHE_00022 29421 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3186A>G None
M0072093 DNJJBEHE_00022 29441 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3206C>T None
M0072094 DNJJBEHE_00022 29446 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3211A>G None
M0072095 DNJJBEHE_00022 29451 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3216T>A None
M0072096 DNJJBEHE_00022 29462 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3227G>T None
M0072097 DNJJBEHE_00022 29499 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3264G>T None
M0072098 DNJJBEHE_00027 29569 6 Skin 0.86 protein_coding synonymous_variant LOW 852G>A Glu284Glu
M0072099 DNJJBEHE_00027 29629 5 Skin 0.71 protein_coding synonymous_variant LOW 792C>T Thr264Thr
M0072100 DNJJBEHE_00027 29650 5 Skin 0.71 protein_coding synonymous_variant LOW 771T>A Pro257Pro
M0072101 DNJJBEHE_00027 29959 6 Skin 0.86 protein_coding synonymous_variant LOW 462G>A Leu154Leu
M0072102 DNJJBEHE_00027 29965 6 Skin 0.86 protein_coding synonymous_variant LOW 456A>G Lys152Lys
M0072103 DNJJBEHE_00027 29983 6 Skin 0.86 protein_coding synonymous_variant LOW 438A>G Gly146Gly
M0072104 DNJJBEHE_00027 30040 6 Skin 0.86 protein_coding synonymous_variant LOW 381A>G Leu127Leu
M0072105 DNJJBEHE_00027 30042 6 Skin 0.86 protein_coding synonymous_variant LOW 379C>T Leu127Leu
M0072106 DNJJBEHE_00027 30073 5 Skin 0.71 protein_coding synonymous_variant LOW 348T>C Ser116Ser
M0072107 DNJJBEHE_00027 30102 6 Skin 0.86 protein_coding missense_variant MODERATE 319T>G Ser107Ala
M0072108 DNJJBEHE_00027 30103 6 Skin 0.86 protein_coding synonymous_variant LOW 318G>T Gly106Gly
M0072109 DNJJBEHE_00027 30282 6 Skin 0.86 protein_coding missense_variant MODERATE 139G>T Ala47Ser
M0072110 DNJJBEHE_00027 30342 5 Skin 0.71 protein_coding missense_variant MODERATE 79C>A His27Asn
M0072111 DNJJBEHE_00022 30438 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -4203T>A None
M0072112 DNJJBEHE_00028 30561 5 Skin 0.71 protein_coding missense_variant MODERATE 8T>C Phe3Ser
M0072113 DNJJBEHE_00028 30697 3 Skin 0.43 protein_coding synonymous_variant LOW 144A>G Ala48Ala
M0072114 DNJJBEHE_00028 30712 3 Skin 0.43 protein_coding synonymous_variant LOW 159T>C Leu53Leu
M0072115 DNJJBEHE_00028 30715 3 Skin 0.43 protein_coding synonymous_variant LOW 162A>G Leu54Leu
M0072116 DNJJBEHE_00028 30859 4 Skin 0.57 protein_coding synonymous_variant LOW 306C>T Asp102Asp
M0072117 DNJJBEHE_00028 30865 4 Skin 0.57 protein_coding synonymous_variant LOW 312T>C Thr104Thr
M0072118 DNJJBEHE_00028 30967 4 Skin 0.57 protein_coding synonymous_variant LOW 414T>C Thr138Thr
M0072119 DNJJBEHE_00023 31424 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -4754T>C None
M0072120 DNJJBEHE_00023 31450 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -4780C>T None
M0072121 DNJJBEHE_00023 31508 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4838T>C None
M0072122 DNJJBEHE_00025 28502 3 Skin 0.43 protein_coding missense_variant MODERATE 209A>T Gln70Leu
M0072123 DNJJBEHE_00025 28503 3 Skin 0.43 protein_coding stop_gained HIGH 208C>T Gln70*
M0072124 DNJJBEHE_00025 28504 3 Skin 0.43 protein_coding synonymous_variant LOW 207C>T Pro69Pro
M0072125 DNJJBEHE_00025 28508 3 Skin 0.43 protein_coding missense_variant MODERATE 203T>A Leu68His
M0072126 DNJJBEHE_00025 28615 3 Skin 0.43 protein_coding synonymous_variant LOW 96G>A Gln32Gln
M0072127 DNJJBEHE_00026 28797 4 Skin 0.57 protein_coding synonymous_variant LOW 516C>T Pro172Pro
M0072128 DNJJBEHE_00026 28860 4 Skin 0.57 protein_coding synonymous_variant LOW 453A>C Thr151Thr
M0072129 DNJJBEHE_00026 29124 4 Skin 0.57 protein_coding synonymous_variant LOW 189G>A Leu63Leu
M0072130 DNJJBEHE_00026 29223 4 Skin 0.57 protein_coding synonymous_variant LOW 90G>A Val30Val
M0072131 DNJJBEHE_00022 29325 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3090C>A None
M0072132 DNJJBEHE_00022 29328 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3093A>T None
M0072133 DNJJBEHE_00022 29469 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -3234C>T None
M0072134 DNJJBEHE_00022 29482 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -3247T>C None
M0072135 DNJJBEHE_00022 29515 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -3280G>A None
M0072136 DNJJBEHE_00022 29531 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -3296C>T None
M0072137 DNJJBEHE_00027 29587 4 Skin 0.57 protein_coding synonymous_variant LOW 834A>G Leu278Leu
M0072138 DNJJBEHE_00027 29830 5 Skin 0.71 protein_coding synonymous_variant LOW 591C>T Ser197Ser
M0072139 DNJJBEHE_00027 29871 5 Skin 0.71 protein_coding synonymous_variant LOW 550C>T Leu184Leu
M0072140 DNJJBEHE_00027 29893 4 Skin 0.57 protein_coding synonymous_variant LOW 528G>A Gln176Gln
M0072141 DNJJBEHE_00027 30268 5 Skin 0.71 protein_coding synonymous_variant LOW 153C>A Ala51Ala
M0072142 DNJJBEHE_00027 30367 3 Skin 0.43 protein_coding synonymous_variant LOW 54G>A Ala18Ala
M0072143 DNJJBEHE_00028 30797 3 Skin 0.43 protein_coding synonymous_variant LOW 244T>C Leu82Leu
M0072144 DNJJBEHE_00028 30880 3 Skin 0.43 protein_coding synonymous_variant LOW 327G>A Arg109Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term