Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3087
  Reference Plasmid   MET0100_bin.2_new__k81_1203
  Reference Plasmid Size   4072
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0074169 KBJCDHMP_00002 709 10 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -189C>T None
M0074170 KBJCDHMP_00003 1401 3 Skin 0.19 protein_coding missense_variant MODERATE 159G>T Met53Ile
M0074171 KBJCDHMP_00005 3444 4 Skin 0.25 protein_coding missense_variant MODERATE 550A>C Ile184Leu
M0074172 KBJCDHMP_00001 230 4 Skin 0.25 protein_coding missense_variant MODERATE 167A>T Tyr56Phe
M0074173 KBJCDHMP_00002 762 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -136T>C None
M0074174 KBJCDHMP_00002 972 5 Skin 0.31 protein_coding missense_variant MODERATE 75A>T Lys25Asn
M0074175 KBJCDHMP_00003 1341 6 Skin 0.38 protein_coding synonymous_variant LOW 99G>A Lys33Lys
M0074176 KBJCDHMP_00003 1356 6 Skin 0.38 protein_coding synonymous_variant LOW 114A>G Leu38Leu
M0074177 KBJCDHMP_00003 1357 6 Skin 0.38 protein_coding synonymous_variant LOW 115A>C Arg39Arg
M0074178 KBJCDHMP_00003 1999 4 Skin 0.25 protein_coding missense_variant MODERATE 757A>G Ser253Gly
M0074179 KBJCDHMP_00003 2019 4 Skin 0.25 protein_coding missense_variant MODERATE 777T>G His259Gln
M0074180 KBJCDHMP_00003 2040 4 Skin 0.25 protein_coding synonymous_variant LOW 798T>C His266His
M0074181 KBJCDHMP_00004 2285 4 Skin 0.25 protein_coding missense_variant MODERATE 183T>A Asn61Lys
M0074182 KBJCDHMP_00001 309 3 Skin 0.19 protein_coding synonymous_variant LOW 246C>T Gly82Gly
M0074183 KBJCDHMP_00002 923 3 Skin 0.19 protein_coding missense_variant MODERATE 26A>G Asn9Ser
M0074184 KBJCDHMP_00002 957 3 Skin 0.19 protein_coding synonymous_variant LOW 60T>C Ile20Ile
M0074185 KBJCDHMP_00002 1095 3 Skin 0.19 protein_coding synonymous_variant LOW 198C>T Leu66Leu
M0074186 KBJCDHMP_00002 1101 3 Skin 0.19 protein_coding missense_variant MODERATE 204G>A Met68Ile
M0074187 KBJCDHMP_00002 1132 4 Skin 0.25 protein_coding missense_variant MODERATE 235A>G Ile79Val
M0074188 KBJCDHMP_00003 1218 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -25C>G None
M0074189 KBJCDHMP_00003 1222 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -21A>T None
M0074190 KBJCDHMP_00003 1337 4 Skin 0.25 protein_coding missense_variant MODERATE 95G>A Gly32Asp
M0074191 KBJCDHMP_00003 1383 5 Skin 0.31 protein_coding missense_variant MODERATE 141G>C Gln47His
M0074192 KBJCDHMP_00004 2471 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4T>C None
M0074193 KBJCDHMP_00004 2508 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -41A>G None
M0074194 KBJCDHMP_00004 2566 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -99A>G None
M0074195 KBJCDHMP_00004 2682 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -215A>G None
M0074196 KBJCDHMP_00004 2705 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -238A>G None
M0074197 KBJCDHMP_00004 2706 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -239G>A None
M0074198 KBJCDHMP_00004 2756 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -289C>A None
M0074199 KBJCDHMP_00004 2837 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -370A>T None
M0074200 KBJCDHMP_00004 2865 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -398A>G None
M0074201 KBJCDHMP_00005 3287 3 Skin 0.19 protein_coding missense_variant MODERATE 707T>C Leu236Ser
M0074202 KBJCDHMP_00004 2631 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -164T>G None
M0074203 KBJCDHMP_00004 2632 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -165A>T None
M0074204 KBJCDHMP_00004 2643 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -176C>A None
M0074205 KBJCDHMP_00004 2648 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -181A>G None
M0074206 KBJCDHMP_00004 2676 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -209G>A None
M0074207 KBJCDHMP_00004 2696 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -229C>A None
M0074208 KBJCDHMP_00004 2709 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -242T>C None
M0074209 KBJCDHMP_00004 2719 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -252A>T None
M0074210 KBJCDHMP_00004 2749 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -282C>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term