Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3110
  Reference Plasmid   MET0207_bin.13__k81_683179
  Reference Plasmid Size   2915
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0075669 NBPKAMGA_00002 1297 3 Skin 1.00 protein_coding missense_variant MODERATE 23A>G Asn8Ser
M0075670 NBPKAMGA_00002 1445 3 Skin 1.00 protein_coding synonymous_variant LOW 171T>C Ala57Ala
M0075671 NBPKAMGA_00002 1471 3 Skin 1.00 protein_coding missense_variant MODERATE 197T>C Val66Ala
M0075672 NBPKAMGA_00002 1503 3 Skin 1.00 protein_coding missense_variant MODERATE 229C>G Arg77Gly
M0075673 NBPKAMGA_00002 1526 3 Skin 1.00 protein_coding synonymous_variant LOW 252G>A Glu84Glu
M0075674 NBPKAMGA_00002 1772 3 Skin 1.00 protein_coding synonymous_variant LOW 498T>C Phe166Phe
M0075675 NBPKAMGA_00002 1788 3 Skin 1.00 protein_coding synonymous_variant LOW 514T>C Leu172Leu
M0075676 NBPKAMGA_00002 1871 3 Skin 1.00 protein_coding synonymous_variant LOW 597G>C Ala199Ala
M0075677 NBPKAMGA_00002 1884 3 Skin 1.00 protein_coding missense_variant MODERATE 610G>A Asp204Asn
M0075678 NBPKAMGA_00002 1917 3 Skin 1.00 protein_coding missense_variant MODERATE 643G>A Ala215Thr
M0075679 NBPKAMGA_00002 1925 3 Skin 1.00 protein_coding missense_variant MODERATE 651C>G Asp217Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
NBPKAMGA_00003 Cobalt (Co), Nickel (Ni) 98.3 2.9e-62 1 119 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term