Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3113
  Reference Plasmid   MET0207_bin.66__k81_130797
  Reference Plasmid Size   6859
  Reference Plasmid GC Content   0.75
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0075719 HABHIONO_00005 4540 3 Skin 0.50 protein_coding synonymous_variant LOW 1125G>C Ala375Ala
M0075720 HABHIONO_00005 4597 3 Skin 0.50 protein_coding synonymous_variant LOW 1182T>C Gly394Gly
M0075721 HABHIONO_00005 4637 3 Skin 0.50 protein_coding synonymous_variant LOW 1222T>C Leu408Leu
M0075722 HABHIONO_00005 4785 4 Skin 0.67 protein_coding missense_variant MODERATE 1370G>C Gly457Ala
M0075723 HABHIONO_00001 4980 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4410C>T None
M0075724 HABHIONO_00001 5058 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4488A>C None
M0075725 HABHIONO_00006 5258 3 Skin 0.50 protein_coding missense_variant MODERATE 191T>G Val64Gly
M0075726 HABHIONO_00006 5348 5 Skin 0.83 protein_coding missense_variant MODERATE 281A>G Glu94Gly
M0075727 HABHIONO_00006 5370 4 Skin 0.67 protein_coding synonymous_variant LOW 303G>A Glu101Glu
M0075728 HABHIONO_00006 5379 5 Skin 0.83 protein_coding synonymous_variant LOW 312A>G Ala104Ala
M0075729 HABHIONO_00007 5672 4 Skin 0.67 protein_coding missense_variant MODERATE 50G>C Gly17Ala
M0075730 HABHIONO_00007 5794 3 Skin 0.50 protein_coding missense_variant MODERATE 172G>C Glu58Gln
M0075731 HABHIONO_00007 5869 4 Skin 0.67 protein_coding missense_variant MODERATE 247G>A Val83Ile
M0075732 HABHIONO_00007 5880 4 Skin 0.67 protein_coding synonymous_variant LOW 258C>G Val86Val
M0075733 HABHIONO_00007 5958 3 Skin 0.50 protein_coding synonymous_variant LOW 336C>G Leu112Leu
M0075734 HABHIONO_00007 5960 3 Skin 0.50 protein_coding missense_variant MODERATE 338G>A Arg113Gln
M0075735 HABHIONO_00002 6212 5 Skin 0.83 protein_coding upstream_gene_variant MODIFIER -4555A>C None
M0075736 HABHIONO_00002 6237 5 Skin 0.83 protein_coding upstream_gene_variant MODIFIER -4580G>C None
M0075737 HABHIONO_00002 6238 5 Skin 0.83 protein_coding upstream_gene_variant MODIFIER -4581C>T None
M0075738 HABHIONO_00009 6502 6 Skin 1.00 protein_coding missense_variant MODERATE 244A>C Ile82Leu
M0075739 HABHIONO_00005 4888 4 Skin 0.67 protein_coding synonymous_variant LOW 1473C>T His491His
M0075740 HABHIONO_00006 5456 3 Skin 0.50 protein_coding missense_variant MODERATE 389C>T Ala130Val
M0075741 HABHIONO_00006 5474 3 Skin 0.50 protein_coding missense_variant MODERATE 407C>A Ser136Tyr
M0075742 HABHIONO_00006 5535 3 Skin 0.50 protein_coding synonymous_variant LOW 468T>C Ser156Ser
M0075743 HABHIONO_00006 5538 3 Skin 0.50 protein_coding synonymous_variant LOW 471C>T His157His
M0075744 HABHIONO_00007 5697 3 Skin 0.50 protein_coding synonymous_variant LOW 75T>C Asp25Asp
M0075745 HABHIONO_00007 5725 5 Skin 0.83 protein_coding missense_variant MODERATE 103A>G Thr35Ala
M0075746 HABHIONO_00007 5726 5 Skin 0.83 protein_coding missense_variant MODERATE 104C>T Thr35Met
M0075747 HABHIONO_00003 6791 4 Skin 0.67 protein_coding downstream_gene_variant MODIFIER *4166G>A None
M0075748 HABHIONO_00005 4162 3 Skin 0.50 protein_coding synonymous_variant LOW 747G>C Val249Val
M0075749 HABHIONO_00005 4251 3 Skin 0.50 protein_coding missense_variant MODERATE 836A>C Asn279Thr
M0075750 HABHIONO_00005 4265 3 Skin 0.50 protein_coding missense_variant MODERATE 850A>G Thr284Ala
M0075751 HABHIONO_00005 4336 3 Skin 0.50 protein_coding synonymous_variant LOW 921C>T His307His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term