Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3120
  Reference Plasmid   MET0213_bin.2__k81_9002
  Reference Plasmid Size   6633
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0076042 MCJCAMFK_00002 929 4 Skin 0.40 protein_coding synonymous_variant LOW 21G>T Arg7Arg
M0076043 MCJCAMFK_00002 953 4 Skin 0.40 protein_coding synonymous_variant LOW 45C>T Ser15Ser
M0076044 MCJCAMFK_00002 995 4 Skin 0.40 protein_coding synonymous_variant LOW 87C>T Gly29Gly
M0076045 MCJCAMFK_00002 1007 4 Skin 0.40 protein_coding synonymous_variant LOW 99C>T Val33Val
M0076046 MCJCAMFK_00002 1070 4 Skin 0.40 protein_coding synonymous_variant LOW 162G>T Leu54Leu
M0076047 MCJCAMFK_00002 1071 4 Skin 0.40 protein_coding missense_variant MODERATE 163A>G Ile55Val
M0076048 MCJCAMFK_00002 1073 4 Skin 0.40 protein_coding synonymous_variant LOW 165C>T Ile55Ile
M0076049 MCJCAMFK_00002 1076 4 Skin 0.40 protein_coding synonymous_variant LOW 168G>A Glu56Glu
M0076050 MCJCAMFK_00002 1079 4 Skin 0.40 protein_coding synonymous_variant LOW 171C>T Ile57Ile
M0076051 MCJCAMFK_00002 1080 4 Skin 0.40 protein_coding missense_variant MODERATE 172A>G Ser58Gly
M0076052 MCJCAMFK_00002 1088 4 Skin 0.40 protein_coding synonymous_variant LOW 180T>C Ala60Ala
M0076053 MCJCAMFK_00002 1106 4 Skin 0.40 protein_coding synonymous_variant LOW 198G>A Glu66Glu
M0076054 MCJCAMFK_00002 1130 4 Skin 0.40 protein_coding synonymous_variant LOW 222T>C Val74Val
M0076055 MCJCAMFK_00002 1136 4 Skin 0.40 protein_coding synonymous_variant LOW 228T>C Ala76Ala
M0076056 MCJCAMFK_00002 1148 4 Skin 0.40 protein_coding synonymous_variant LOW 240G>A Pro80Pro
M0076057 MCJCAMFK_00002 1157 4 Skin 0.40 protein_coding synonymous_variant LOW 249T>C Thr83Thr
M0076058 MCJCAMFK_00002 1184 4 Skin 0.40 protein_coding synonymous_variant LOW 276C>T Ser92Ser
M0076059 MCJCAMFK_00002 1204 6 Skin 0.60 protein_coding missense_variant MODERATE 296T>C Leu99Pro
M0076060 MCJCAMFK_00002 1208 4 Skin 0.40 protein_coding synonymous_variant LOW 300T>C Cys100Cys
M0076061 MCJCAMFK_00002 1221 4 Skin 0.40 protein_coding missense_variant MODERATE 313G>T Ala105Ser
M0076062 MCJCAMFK_00002 1223 4 Skin 0.40 protein_coding synonymous_variant LOW 315T>C Ala105Ala
M0076063 MCJCAMFK_00003 1268 3 Skin 0.30 protein_coding missense_variant MODERATE 25T>C Cys9Arg
M0076064 MCJCAMFK_00003 1335 4 Skin 0.40 protein_coding missense_variant MODERATE 92C>T Ala31Val
M0076065 MCJCAMFK_00003 1463 4 Skin 0.40 protein_coding missense_variant MODERATE 220G>A Ala74Thr
M0076066 MCJCAMFK_00003 1501 4 Skin 0.40 protein_coding synonymous_variant LOW 258A>G Val86Val
M0076067 MCJCAMFK_00003 1502 4 Skin 0.40 protein_coding missense_variant MODERATE 259G>A Val87Ile
M0076068 MCJCAMFK_00003 1524 4 Skin 0.40 protein_coding missense_variant MODERATE 281A>G His94Arg
M0076069 MCJCAMFK_00003 1549 4 Skin 0.40 protein_coding synonymous_variant LOW 306A>C Arg102Arg
M0076070 MCJCAMFK_00003 1566 4 Skin 0.40 protein_coding missense_variant MODERATE 323C>A Pro108Gln
M0076071 MCJCAMFK_00003 1568 4 Skin 0.40 protein_coding missense_variant MODERATE 325G>A Asp109Asn
M0076072 MCJCAMFK_00003 1588 4 Skin 0.40 protein_coding synonymous_variant LOW 345T>C Tyr115Tyr
M0076073 MCJCAMFK_00003 1606 4 Skin 0.40 protein_coding synonymous_variant LOW 363C>A Arg121Arg
M0076074 MCJCAMFK_00003 1609 4 Skin 0.40 protein_coding synonymous_variant LOW 366C>A Arg122Arg
M0076075 MCJCAMFK_00004 2131 6 Skin 0.60 protein_coding synonymous_variant LOW 219T>C Asp73Asp
M0076076 MCJCAMFK_00005 2439 6 Skin 0.60 protein_coding missense_variant MODERATE 6A>C Arg2Ser
M0076077 MCJCAMFK_00005 2547 6 Skin 0.60 protein_coding synonymous_variant LOW 114C>T Ile38Ile
M0076078 MCJCAMFK_00005 2814 5 Skin 0.50 protein_coding synonymous_variant LOW 381G>A Ala127Ala
M0076079 MCJCAMFK_00005 2829 6 Skin 0.60 protein_coding synonymous_variant LOW 396T>C Pro132Pro
M0076080 MCJCAMFK_00005 2847 6 Skin 0.60 protein_coding synonymous_variant LOW 414A>G Pro138Pro
M0076081 MCJCAMFK_00005 2848 6 Skin 0.60 protein_coding missense_variant MODERATE 415A>G Ile139Val
M0076082 MCJCAMFK_00005 2856 6 Skin 0.60 protein_coding synonymous_variant LOW 423C>T Ala141Ala
M0076083 MCJCAMFK_00005 2865 6 Skin 0.60 protein_coding synonymous_variant LOW 432A>C Ala144Ala
M0076084 MCJCAMFK_00005 3067 6 Skin 0.60 protein_coding missense_variant MODERATE 634A>C Asn212His
M0076085 MCJCAMFK_00005 3108 6 Skin 0.60 protein_coding synonymous_variant LOW 675T>G Pro225Pro
M0076086 MCJCAMFK_00005 3114 6 Skin 0.60 protein_coding synonymous_variant LOW 681C>A Gly227Gly
M0076087 MCJCAMFK_00005 3117 6 Skin 0.60 protein_coding synonymous_variant LOW 684T>C Pro228Pro
M0076088 MCJCAMFK_00005 3132 6 Skin 0.60 protein_coding synonymous_variant LOW 699G>A Val233Val
M0076089 MCJCAMFK_00005 3136 6 Skin 0.60 protein_coding missense_variant MODERATE 703A>G Ile235Val
M0076090 MCJCAMFK_00005 3138 6 Skin 0.60 protein_coding missense_variant MODERATE 705C>G Ile235Met
M0076091 MCJCAMFK_00005 3156 6 Skin 0.60 protein_coding synonymous_variant LOW 723T>C Tyr241Tyr
M0076092 MCJCAMFK_00005 3198 6 Skin 0.60 protein_coding synonymous_variant LOW 765T>C Thr255Thr
M0076093 MCJCAMFK_00005 3487 6 Skin 0.60 protein_coding synonymous_variant LOW 1054T>C Leu352Leu
M0076094 MCJCAMFK_00005 3585 6 Skin 0.60 protein_coding synonymous_variant LOW 1152G>C Thr384Thr
M0076095 MCJCAMFK_00005 3587 6 Skin 0.60 protein_coding missense_variant MODERATE 1154C>A Thr385Lys
M0076096 MCJCAMFK_00005 3588 6 Skin 0.60 protein_coding synonymous_variant LOW 1155A>G Thr385Thr
M0076097 MCJCAMFK_00005 3598 6 Skin 0.60 protein_coding missense_variant MODERATE 1165T>G Ser389Ala
M0076098 MCJCAMFK_00005 3604 6 Skin 0.60 protein_coding synonymous_variant LOW 1171T>C Leu391Leu
M0076099 MCJCAMFK_00005 3672 5 Skin 0.50 protein_coding synonymous_variant LOW 1239C>T Val413Val
M0076100 MCJCAMFK_00005 3795 5 Skin 0.50 protein_coding synonymous_variant LOW 1362T>C His454His
M0076101 MCJCAMFK_00005 3909 4 Skin 0.40 protein_coding missense_variant MODERATE 1476G>A Met492Ile
M0076102 MCJCAMFK_00005 3930 5 Skin 0.50 protein_coding synonymous_variant LOW 1497T>C Ala499Ala
M0076103 MCJCAMFK_00002 219 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -690G>A None
M0076104 MCJCAMFK_00002 309 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -600G>A None
M0076105 MCJCAMFK_00001 338 3 Skin 0.30 protein_coding missense_variant MODERATE 434G>A Arg145Gln
M0076106 MCJCAMFK_00001 347 3 Skin 0.30 protein_coding missense_variant MODERATE 425C>G Ala142Gly
M0076107 MCJCAMFK_00001 367 3 Skin 0.30 protein_coding synonymous_variant LOW 405A>G Ala135Ala
M0076108 MCJCAMFK_00001 594 3 Skin 0.30 protein_coding missense_variant MODERATE 178A>G Lys60Glu
M0076109 MCJCAMFK_00001 654 3 Skin 0.30 protein_coding missense_variant MODERATE 118T>C Cys40Arg
M0076110 MCJCAMFK_00001 664 3 Skin 0.30 protein_coding synonymous_variant LOW 108C>T Pro36Pro
M0076111 MCJCAMFK_00001 671 3 Skin 0.30 protein_coding missense_variant MODERATE 101A>G His34Arg
M0076112 MCJCAMFK_00001 682 3 Skin 0.30 protein_coding synonymous_variant LOW 90T>C Ser30Ser
M0076113 MCJCAMFK_00001 739 3 Skin 0.30 protein_coding synonymous_variant LOW 33T>G Ser11Ser
M0076114 MCJCAMFK_00001 798 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -27C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term