Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3127
  Reference Plasmid   MET0223_bin.16__k81_125415
  Reference Plasmid Size   15812
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0076147 OGCNMJFH_00001 66 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -46C>T None
M0076148 OGCNMJFH_00001 71 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -41G>A None
M0076149 OGCNMJFH_00001 81 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -31C>T None
M0076150 OGCNMJFH_00001 132 3 Skin 0.50 protein_coding synonymous_variant LOW 21C>T Ser7Ser
M0076151 OGCNMJFH_00001 270 3 Skin 0.50 protein_coding synonymous_variant LOW 159A>C Ala53Ala
M0076152 OGCNMJFH_00001 464 3 Skin 0.50 protein_coding missense_variant MODERATE 353T>C Met118Thr
M0076153 OGCNMJFH_00001 471 3 Skin 0.50 protein_coding synonymous_variant LOW 360T>C Phe120Phe
M0076154 OGCNMJFH_00002 861 3 Skin 0.50 protein_coding missense_variant MODERATE 223A>G Arg75Gly
M0076155 OGCNMJFH_00002 926 3 Skin 0.50 protein_coding synonymous_variant LOW 288C>A Arg96Arg
M0076156 OGCNMJFH_00002 1242 3 Skin 0.50 protein_coding missense_variant MODERATE 604G>A Val202Met
M0076157 OGCNMJFH_00002 1357 3 Skin 0.50 protein_coding missense_variant MODERATE 719T>C Val240Ala
M0076158 OGCNMJFH_00021 13690 3 Skin 0.50 protein_coding synonymous_variant LOW 159G>A Ala53Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term