Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3134
  Reference Plasmid   MET0227_bin.3__k81_8863
  Reference Plasmid Size   8778
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0076329 BCPOPFNK_00006 5370 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -216T>C None
M0076330 BCPOPFNK_00006 5773 3 Skin 0.50 protein_coding missense_variant MODERATE 188A>G Gln63Arg
M0076331 BCPOPFNK_00007 5881 3 Skin 0.50 protein_coding synonymous_variant LOW 6T>C Arg2Arg
M0076332 BCPOPFNK_00007 6188 3 Skin 0.50 protein_coding missense_variant MODERATE 313G>C Glu105Gln
M0076333 BCPOPFNK_00007 6389 4 Skin 0.67 protein_coding missense_variant MODERATE 514G>C Val172Leu
M0076334 BCPOPFNK_00007 6966 3 Skin 0.50 protein_coding missense_variant MODERATE 1091G>A Gly364Glu
M0076335 BCPOPFNK_00007 7108 3 Skin 0.50 protein_coding synonymous_variant LOW 1233C>T Ala411Ala
M0076336 BCPOPFNK_00007 7158 4 Skin 0.67 protein_coding missense_variant MODERATE 1283G>A Gly428Asp
M0076337 BCPOPFNK_00007 7557 3 Skin 0.50 protein_coding missense_variant MODERATE 1682T>C Val561Ala
M0076338 BCPOPFNK_00008 7967 4 Skin 0.67 protein_coding synonymous_variant LOW 99T>C Arg33Arg
M0076339 BCPOPFNK_00008 7978 3 Skin 0.50 protein_coding missense_variant MODERATE 110T>C Met37Thr
M0076340 BCPOPFNK_00008 8033 4 Skin 0.67 protein_coding synonymous_variant LOW 165C>T Phe55Phe
M0076341 BCPOPFNK_00008 8220 4 Skin 0.67 protein_coding missense_variant MODERATE 352A>C Thr118Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term