Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3150
  Reference Plasmid   MET0259_bin.32__k81_17194
  Reference Plasmid Size   5814
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0076455 IJIECEEA_00001 531 3 Skin 0.38 protein_coding synonymous_variant LOW 441T>C Gly147Gly
M0076456 IJIECEEA_00001 606 4 Skin 0.50 protein_coding synonymous_variant LOW 366G>C Ala122Ala
M0076457 IJIECEEA_00001 648 3 Skin 0.38 protein_coding synonymous_variant LOW 324C>G Arg108Arg
M0076458 IJIECEEA_00001 691 5 Skin 0.63 protein_coding missense_variant MODERATE 281T>C Val94Ala
M0076459 IJIECEEA_00001 771 4 Skin 0.50 protein_coding synonymous_variant LOW 201T>C His67His
M0076460 IJIECEEA_00001 944 5 Skin 0.63 protein_coding missense_variant MODERATE 28G>A Ala10Thr
M0076461 IJIECEEA_00001 959 5 Skin 0.63 protein_coding missense_variant MODERATE 13A>C Thr5Pro
M0076462 IJIECEEA_00001 1017 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -46A>G None
M0076463 IJIECEEA_00001 1025 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -54T>C None
M0076464 IJIECEEA_00002 1313 3 Skin 0.38 protein_coding missense_variant MODERATE 181G>A Ala61Thr
M0076465 IJIECEEA_00002 1621 4 Skin 0.50 protein_coding synonymous_variant LOW 489G>C Arg163Arg
M0076466 IJIECEEA_00002 1742 3 Skin 0.38 protein_coding missense_variant MODERATE 610T>G Ser204Ala
M0076467 IJIECEEA_00002 1796 3 Skin 0.38 protein_coding missense_variant MODERATE 664A>C Lys222Gln
M0076468 IJIECEEA_00002 1942 4 Skin 0.50 protein_coding synonymous_variant LOW 810A>G Ala270Ala
M0076469 IJIECEEA_00002 2200 3 Skin 0.38 protein_coding synonymous_variant LOW 1068T>C Gly356Gly
M0076470 IJIECEEA_00002 2203 3 Skin 0.38 protein_coding synonymous_variant LOW 1071G>C Gly357Gly
M0076471 IJIECEEA_00002 2273 4 Skin 0.50 protein_coding missense_variant MODERATE 1141A>G Lys381Glu
M0076472 IJIECEEA_00002 2404 6 Skin 0.75 protein_coding synonymous_variant LOW 1272T>C Thr424Thr
M0076473 IJIECEEA_00002 2530 4 Skin 0.50 protein_coding synonymous_variant LOW 1398T>C Gly466Gly
M0076474 IJIECEEA_00002 2560 4 Skin 0.50 protein_coding synonymous_variant LOW 1428A>C Ala476Ala
M0076475 IJIECEEA_00003 2847 4 Skin 0.50 protein_coding synonymous_variant LOW 156G>C Ala52Ala
M0076476 IJIECEEA_00003 3327 3 Skin 0.38 protein_coding synonymous_variant LOW 636T>C Gly212Gly
M0076477 IJIECEEA_00003 3336 3 Skin 0.38 protein_coding synonymous_variant LOW 645G>C Ala215Ala
M0076478 IJIECEEA_00003 3366 3 Skin 0.38 protein_coding synonymous_variant LOW 675C>T Gly225Gly
M0076479 IJIECEEA_00003 3699 3 Skin 0.38 protein_coding synonymous_variant LOW 1008T>C Phe336Phe
M0076480 IJIECEEA_00003 3945 3 Skin 0.38 protein_coding synonymous_variant LOW 1254T>C Ala418Ala
M0076481 IJIECEEA_00003 4105 4 Skin 0.50 protein_coding missense_variant MODERATE 1414A>C Met472Leu
M0076482 IJIECEEA_00003 4155 5 Skin 0.63 protein_coding synonymous_variant LOW 1464G>C Val488Val
M0076483 IJIECEEA_00003 4161 5 Skin 0.63 protein_coding synonymous_variant LOW 1470G>C Thr490Thr
M0076484 IJIECEEA_00003 4287 6 Skin 0.75 protein_coding synonymous_variant LOW 1596C>G Pro532Pro
M0076485 IJIECEEA_00003 4332 3 Skin 0.38 protein_coding synonymous_variant LOW 1641C>G Pro547Pro
M0076486 IJIECEEA_00004 4393 6 Skin 0.75 protein_coding missense_variant MODERATE 44G>A Gly15Asp
M0076487 IJIECEEA_00004 4443 4 Skin 0.50 protein_coding missense_variant MODERATE 94G>C Val32Leu
M0076488 IJIECEEA_00004 4472 3 Skin 0.38 protein_coding synonymous_variant LOW 123C>T Arg41Arg
M0076489 IJIECEEA_00004 4475 4 Skin 0.50 protein_coding synonymous_variant LOW 126A>G Ala42Ala
M0076490 IJIECEEA_00004 4547 4 Skin 0.50 protein_coding synonymous_variant LOW 198A>G Lys66Lys
M0076491 IJIECEEA_00004 4690 4 Skin 0.50 protein_coding missense_variant MODERATE 341A>T Tyr114Phe
M0076492 IJIECEEA_00004 4693 4 Skin 0.50 protein_coding missense_variant MODERATE 344G>A Gly115Glu
M0076493 IJIECEEA_00004 4913 3 Skin 0.38 protein_coding synonymous_variant LOW 564C>G Val188Val
M0076494 IJIECEEA_00004 5247 5 Skin 0.63 protein_coding missense_variant MODERATE 898A>G Thr300Ala
M0076495 IJIECEEA_00004 5479 6 Skin 0.75 protein_coding missense_variant MODERATE 1130C>A Ala377Glu
M0076496 IJIECEEA_00004 5501 5 Skin 0.63 protein_coding synonymous_variant LOW 1152T>C Ala384Ala
M0076497 IJIECEEA_00004 5558 4 Skin 0.50 protein_coding synonymous_variant LOW 1209T>C Ala403Ala
M0076498 IJIECEEA_00004 5649 4 Skin 0.50 protein_coding missense_variant MODERATE 1300A>G Ile434Val
M0076499 IJIECEEA_00002 80 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -1053G>C None
M0076500 IJIECEEA_00002 83 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -1050T>C None
M0076501 IJIECEEA_00002 142 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -991G>T None
M0076502 IJIECEEA_00002 204 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -929T>G None
M0076503 IJIECEEA_00002 223 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -910T>C None
M0076504 IJIECEEA_00002 228 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -905T>G None
M0076505 IJIECEEA_00001 780 3 Skin 0.38 protein_coding missense_variant MODERATE 192C>G Ser64Arg
M0076506 IJIECEEA_00001 782 3 Skin 0.38 protein_coding missense_variant MODERATE 190A>C Ser64Arg
M0076507 IJIECEEA_00002 1753 3 Skin 0.38 protein_coding synonymous_variant LOW 621G>C Ala207Ala
M0076508 IJIECEEA_00004 4742 3 Skin 0.38 protein_coding synonymous_variant LOW 393C>G Gly131Gly
M0076509 IJIECEEA_00004 5090 3 Skin 0.38 protein_coding synonymous_variant LOW 741T>C Asp247Asp
M0076510 IJIECEEA_00002 183 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -950C>A None
M0076511 IJIECEEA_00002 185 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -948G>A None
M0076512 IJIECEEA_00002 186 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -947C>T None
M0076513 IJIECEEA_00002 226 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -907G>A None
M0076514 IJIECEEA_00002 253 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -880A>C None
M0076515 IJIECEEA_00002 261 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -872C>T None
M0076516 IJIECEEA_00002 277 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -856C>G None
M0076517 IJIECEEA_00001 297 3 Skin 0.38 protein_coding synonymous_variant LOW 675G>C Leu225Leu
M0076518 IJIECEEA_00001 1096 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -125G>A None
M0076519 IJIECEEA_00002 1267 3 Skin 0.38 protein_coding synonymous_variant LOW 135G>T Ala45Ala
M0076520 IJIECEEA_00003 3804 3 Skin 0.38 protein_coding synonymous_variant LOW 1113C>T Ala371Ala
M0076521 IJIECEEA_00003 4140 3 Skin 0.38 protein_coding synonymous_variant LOW 1449G>C Ser483Ser
M0076522 IJIECEEA_00003 4152 3 Skin 0.38 protein_coding synonymous_variant LOW 1461C>T Gly487Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term