Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3151
  Reference Plasmid   MET0260_bin.2__k81_10939
  Reference Plasmid Size   10870
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0141329 LOBPIGAF_00002 1405 3 Vaginal 0.60 protein_coding missense_variant MODERATE 2751G>T Lys917Asn
M0141330 LOBPIGAF_00003 5619 3 Vaginal 0.60 protein_coding synonymous_variant LOW 768A>C Thr256Thr
M0141331 LOBPIGAF_00003 5640 3 Vaginal 0.60 protein_coding synonymous_variant LOW 747A>G Gly249Gly
M0141332 LOBPIGAF_00003 5643 3 Vaginal 0.60 protein_coding synonymous_variant LOW 744G>T Ala248Ala
M0141333 LOBPIGAF_00003 5652 3 Vaginal 0.60 protein_coding synonymous_variant LOW 735T>C Val245Val
M0141334 LOBPIGAF_00003 5670 3 Vaginal 0.60 protein_coding synonymous_variant LOW 717A>G Lys239Lys
M0141335 LOBPIGAF_00003 5676 3 Vaginal 0.60 protein_coding synonymous_variant LOW 711G>A Leu237Leu
M0141336 LOBPIGAF_00003 5691 3 Vaginal 0.60 protein_coding synonymous_variant LOW 696A>T Pro232Pro
M0141337 LOBPIGAF_00003 6159 3 Vaginal 0.60 protein_coding synonymous_variant LOW 228C>T Tyr76Tyr
M0141338 LOBPIGAF_00003 6174 3 Vaginal 0.60 protein_coding synonymous_variant LOW 213C>T Gly71Gly
M0141339 LOBPIGAF_00003 6218 3 Vaginal 0.60 protein_coding missense_variant MODERATE 169C>A Arg57Ser
M0141340 LOBPIGAF_00003 6258 3 Vaginal 0.60 protein_coding synonymous_variant LOW 129T>C Gly43Gly
M0141341 LOBPIGAF_00002 6413 3 Vaginal 0.60 protein_coding upstream_gene_variant MODIFIER -2258C>T None
M0141342 LOBPIGAF_00002 6492 3 Vaginal 0.60 protein_coding upstream_gene_variant MODIFIER -2337T>C None
M0141343 LOBPIGAF_00004 6623 3 Vaginal 0.60 protein_coding missense_variant MODERATE 67G>T Gly23Cys
M0141344 LOBPIGAF_00004 6650 3 Vaginal 0.60 protein_coding missense_variant MODERATE 40G>T Ala14Ser
M0141345 LOBPIGAF_00004 6651 3 Vaginal 0.60 protein_coding synonymous_variant LOW 39G>A Ser13Ser
M0141346 LOBPIGAF_00004 6660 3 Vaginal 0.60 protein_coding synonymous_variant LOW 30G>A Thr10Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term