Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3156
  Reference Plasmid   MET0279_bin.1__k81_36829
  Reference Plasmid Size   9141
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0076608 CNGNBIEH_00001 410 3 Skin 0.25 protein_coding missense_variant MODERATE 391G>A Ala131Thr
M0076609 CNGNBIEH_00001 446 3 Skin 0.25 protein_coding missense_variant MODERATE 427C>G His143Asp
M0076610 CNGNBIEH_00001 449 3 Skin 0.25 protein_coding missense_variant MODERATE 430G>C Gly144Arg
M0076611 CNGNBIEH_00001 452 3 Skin 0.25 protein_coding missense_variant MODERATE 433C>G Pro145Ala
M0076612 CNGNBIEH_00001 479 3 Skin 0.25 protein_coding missense_variant MODERATE 460G>A Gly154Arg
M0076613 CNGNBIEH_00001 491 4 Skin 0.33 protein_coding missense_variant MODERATE 472C>A Gln158Lys
M0076614 CNGNBIEH_00001 496 4 Skin 0.33 protein_coding synonymous_variant LOW 477C>T Leu159Leu
M0076615 CNGNBIEH_00001 497 4 Skin 0.33 protein_coding missense_variant MODERATE 478A>C Ile160Leu
M0076616 CNGNBIEH_00001 590 3 Skin 0.25 protein_coding stop_lost&splice_region_variant HIGH 571T>C Ter191Glnext*?
M0076617 CNGNBIEH_00002 602 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -105G>A None
M0076618 CNGNBIEH_00004 4926 9 Skin 0.75 protein_coding missense_variant MODERATE 865C>A Pro289Thr
M0076619 CNGNBIEH_00004 5001 3 Skin 0.25 protein_coding missense_variant MODERATE 790A>T Thr264Ser
M0076620 CNGNBIEH_00004 5049 3 Skin 0.25 protein_coding missense_variant MODERATE 742C>T His248Tyr
M0076621 CNGNBIEH_00004 5089 3 Skin 0.25 protein_coding synonymous_variant LOW 702C>T Asn234Asn
M0076622 CNGNBIEH_00004 5149 5 Skin 0.42 protein_coding synonymous_variant LOW 642C>T Val214Val
M0076623 CNGNBIEH_00004 5173 3 Skin 0.25 protein_coding synonymous_variant LOW 618C>T Ala206Ala
M0076624 CNGNBIEH_00004 5182 5 Skin 0.42 protein_coding synonymous_variant LOW 609T>C Asp203Asp
M0076625 CNGNBIEH_00004 5188 3 Skin 0.25 protein_coding synonymous_variant LOW 603C>T His201His
M0076626 CNGNBIEH_00004 5260 4 Skin 0.33 protein_coding synonymous_variant LOW 531T>C Asp177Asp
M0076627 CNGNBIEH_00005 5973 6 Skin 0.50 protein_coding synonymous_variant LOW 558T>C Thr186Thr
M0076628 CNGNBIEH_00005 6020 3 Skin 0.25 protein_coding missense_variant MODERATE 511A>G Ser171Gly
M0076629 CNGNBIEH_00005 6140 5 Skin 0.42 protein_coding missense_variant MODERATE 391A>G Ile131Val
M0076630 CNGNBIEH_00005 6365 5 Skin 0.42 protein_coding synonymous_variant LOW 166T>C Leu56Leu
M0076631 CNGNBIEH_00005 6518 3 Skin 0.25 protein_coding missense_variant MODERATE 13G>A Val5Ile
M0076632 CNGNBIEH_00006 7076 3 Skin 0.25 protein_coding synonymous_variant LOW 351C>T Val117Val
M0076633 CNGNBIEH_00006 7245 5 Skin 0.42 protein_coding missense_variant MODERATE 182T>G Met61Arg
M0076634 CNGNBIEH_00006 7406 5 Skin 0.42 protein_coding synonymous_variant LOW 21T>G Gly7Gly
M0076635 CNGNBIEH_00007 7489 3 Skin 0.25 protein_coding missense_variant MODERATE 5C>G Thr2Ser
M0076636 CNGNBIEH_00007 7526 3 Skin 0.25 protein_coding synonymous_variant LOW 42G>A Arg14Arg
M0076637 CNGNBIEH_00007 7702 5 Skin 0.42 protein_coding missense_variant MODERATE 218T>C Met73Thr
M0076638 CNGNBIEH_00007 7918 5 Skin 0.42 protein_coding missense_variant MODERATE 434A>G Asn145Ser
M0076639 CNGNBIEH_00007 7998 3 Skin 0.25 protein_coding synonymous_variant LOW 514C>A Arg172Arg
M0076640 CNGNBIEH_00007 8105 5 Skin 0.42 protein_coding synonymous_variant LOW 621T>G Gly207Gly
M0076641 CNGNBIEH_00007 8383 3 Skin 0.25 protein_coding missense_variant MODERATE 899T>G Leu300Arg
M0076642 CNGNBIEH_00003 3661 3 Skin 0.25 protein_coding missense_variant MODERATE 1121C>A Pro374His
M0076643 CNGNBIEH_00003 3747 3 Skin 0.25 protein_coding synonymous_variant LOW 1035G>C Pro345Pro
M0076644 CNGNBIEH_00003 4263 3 Skin 0.25 protein_coding synonymous_variant LOW 519G>C Pro173Pro
M0076645 CNGNBIEH_00003 4275 3 Skin 0.25 protein_coding synonymous_variant LOW 507G>C Gly169Gly
M0076646 CNGNBIEH_00002 2383 3 Skin 0.25 protein_coding synonymous_variant LOW 1677C>G Pro559Pro
M0076647 CNGNBIEH_00002 2398 3 Skin 0.25 protein_coding synonymous_variant LOW 1692T>C Pro564Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term