Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3157
  Reference Plasmid   MET0280_bin.4__k81_12266
  Reference Plasmid Size   4072
  Reference Plasmid GC Content   0.59
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0076648 MMLKLDCA_00001 465 5 Skin 0.45 protein_coding synonymous_variant LOW 456T>G Gly152Gly
M0076649 MMLKLDCA_00001 471 5 Skin 0.45 protein_coding synonymous_variant LOW 462T>C Arg154Arg
M0076650 MMLKLDCA_00001 741 5 Skin 0.45 protein_coding synonymous_variant LOW 732G>A Glu244Glu
M0076651 MMLKLDCA_00001 747 5 Skin 0.45 protein_coding synonymous_variant LOW 738T>C Leu246Leu
M0076652 MMLKLDCA_00001 810 5 Skin 0.45 protein_coding synonymous_variant LOW 801T>C Thr267Thr
M0076653 MMLKLDCA_00001 819 3 Skin 0.27 protein_coding synonymous_variant LOW 810C>T Arg270Arg
M0076654 MMLKLDCA_00002 923 5 Skin 0.45 protein_coding upstream_gene_variant MODIFIER -78G>C None
M0076655 MMLKLDCA_00002 1263 9 Skin 0.82 protein_coding missense_variant MODERATE 263G>C Gly88Ala
M0076656 MMLKLDCA_00001 1656 3 Skin 0.27 protein_coding downstream_gene_variant MODIFIER *762T>C None
M0076657 MMLKLDCA_00001 1713 3 Skin 0.27 protein_coding downstream_gene_variant MODIFIER *819C>T None
M0076658 MMLKLDCA_00001 1828 3 Skin 0.27 protein_coding downstream_gene_variant MODIFIER *934C>T None
M0076659 MMLKLDCA_00003 2000 3 Skin 0.27 protein_coding missense_variant MODERATE 989A>C Lys330Thr
M0076660 MMLKLDCA_00003 2190 7 Skin 0.64 protein_coding missense_variant MODERATE 799G>A Ala267Thr
M0076661 MMLKLDCA_00003 2322 7 Skin 0.64 protein_coding missense_variant MODERATE 667G>A Ala223Thr
M0076662 MMLKLDCA_00003 2363 3 Skin 0.27 protein_coding missense_variant MODERATE 626A>G His209Arg
M0076663 MMLKLDCA_00003 2425 3 Skin 0.27 protein_coding synonymous_variant LOW 564A>G Lys188Lys
M0076664 MMLKLDCA_00003 2532 3 Skin 0.27 protein_coding missense_variant MODERATE 457A>T Ile153Leu
M0076665 MMLKLDCA_00003 2750 3 Skin 0.27 protein_coding missense_variant MODERATE 239C>T Pro80Leu
M0076666 MMLKLDCA_00003 2781 3 Skin 0.27 protein_coding missense_variant MODERATE 208C>T Pro70Ser
M0076667 MMLKLDCA_00003 2789 7 Skin 0.64 protein_coding missense_variant MODERATE 200G>C Ser67Thr
M0076668 MMLKLDCA_00003 2863 3 Skin 0.27 protein_coding synonymous_variant LOW 126T>C Phe42Phe
M0076669 MMLKLDCA_00003 3130 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -142T>G None
M0076670 MMLKLDCA_00003 3162 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -174C>T None
M0076671 MMLKLDCA_00004 3453 3 Skin 0.27 protein_coding missense_variant MODERATE 90T>G Asn30Lys
M0076672 MMLKLDCA_00003 3571 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -583C>T None
M0076673 MMLKLDCA_00003 3592 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -604A>G None
M0076674 MMLKLDCA_00005 3684 3 Skin 0.27 protein_coding missense_variant MODERATE 88C>T Arg30Trp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term