Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3160
  Reference Plasmid   MET0285_bin.1__k81_100972
  Reference Plasmid Size   4483
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0076685 CNALAIBG_00002 1244 3 Skin 0.75 protein_coding synonymous_variant LOW 711C>A Val237Val
M0076686 CNALAIBG_00002 1280 3 Skin 0.75 protein_coding missense_variant MODERATE 747A>T Glu249Asp
M0076687 CNALAIBG_00002 1367 3 Skin 0.75 protein_coding missense_variant MODERATE 834A>G Ile278Met
M0076688 CNALAIBG_00002 1406 3 Skin 0.75 protein_coding synonymous_variant LOW 873G>A Thr291Thr
M0076689 CNALAIBG_00002 1466 3 Skin 0.75 protein_coding missense_variant MODERATE 933C>A His311Gln
M0076690 CNALAIBG_00002 1486 3 Skin 0.75 protein_coding missense_variant MODERATE 953A>G Asp318Gly
M0076691 CNALAIBG_00002 1637 3 Skin 0.75 protein_coding synonymous_variant LOW 1104C>T Tyr368Tyr
M0076692 CNALAIBG_00002 1871 3 Skin 0.75 protein_coding synonymous_variant LOW 1338G>T Thr446Thr
M0076693 CNALAIBG_00002 1905 3 Skin 0.75 protein_coding missense_variant MODERATE 1372T>C Cys458Arg
M0076694 CNALAIBG_00002 1913 3 Skin 0.75 protein_coding synonymous_variant LOW 1380A>G Leu460Leu
M0076695 CNALAIBG_00002 1985 3 Skin 0.75 protein_coding synonymous_variant LOW 1452A>G Leu484Leu
M0076696 CNALAIBG_00002 2015 3 Skin 0.75 protein_coding missense_variant MODERATE 1482A>T Glu494Asp
M0076697 CNALAIBG_00003 2027 3 Skin 0.75 protein_coding synonymous_variant LOW 6G>A Arg2Arg
M0076698 CNALAIBG_00003 2036 3 Skin 0.75 protein_coding synonymous_variant LOW 15T>C Tyr5Tyr
M0076699 CNALAIBG_00003 2105 3 Skin 0.75 protein_coding synonymous_variant LOW 84G>A Gln28Gln
M0076700 CNALAIBG_00003 2108 3 Skin 0.75 protein_coding synonymous_variant LOW 87C>T Phe29Phe
M0076701 CNALAIBG_00003 2171 3 Skin 0.75 protein_coding missense_variant MODERATE 150G>T Arg50Ser
M0076702 CNALAIBG_00003 2190 3 Skin 0.75 protein_coding synonymous_variant LOW 169T>C Leu57Leu
M0076703 CNALAIBG_00003 2219 3 Skin 0.75 protein_coding synonymous_variant LOW 198C>T Ile66Ile
M0076704 CNALAIBG_00003 2234 3 Skin 0.75 protein_coding synonymous_variant LOW 213G>A Glu71Glu
M0076705 CNALAIBG_00003 2271 3 Skin 0.75 protein_coding missense_variant MODERATE 250C>A His84Asn
M0076706 CNALAIBG_00003 2274 3 Skin 0.75 protein_coding missense_variant MODERATE 253G>A Ala85Thr
M0076707 CNALAIBG_00003 2318 3 Skin 0.75 protein_coding synonymous_variant LOW 297G>A Gly99Gly
M0076708 CNALAIBG_00003 2346 3 Skin 0.75 protein_coding missense_variant MODERATE 325T>C Ser109Pro
M0076709 CNALAIBG_00003 2374 3 Skin 0.75 protein_coding missense_variant MODERATE 353A>G Tyr118Cys
M0076710 CNALAIBG_00004 2398 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -54A>G None
M0076711 CNALAIBG_00004 2511 3 Skin 0.75 protein_coding synonymous_variant LOW 60G>A Val20Val
M0076712 CNALAIBG_00004 2536 3 Skin 0.75 protein_coding synonymous_variant LOW 85T>C Leu29Leu
M0076713 CNALAIBG_00004 2564 3 Skin 0.75 protein_coding missense_variant MODERATE 113C>T Ala38Val
M0076714 CNALAIBG_00004 2565 3 Skin 0.75 protein_coding synonymous_variant LOW 114G>A Ala38Ala
M0076715 CNALAIBG_00004 2574 3 Skin 0.75 protein_coding synonymous_variant LOW 123G>A Gln41Gln
M0076716 CNALAIBG_00004 2586 3 Skin 0.75 protein_coding synonymous_variant LOW 135A>C Pro45Pro
M0076717 CNALAIBG_00004 2609 4 Skin 1.00 protein_coding missense_variant MODERATE 158T>C Leu53Ser
M0076718 CNALAIBG_00004 2679 3 Skin 0.75 protein_coding synonymous_variant LOW 228G>A Gly76Gly
M0076719 CNALAIBG_00004 2727 3 Skin 0.75 protein_coding synonymous_variant LOW 276C>T Ala92Ala
M0076720 CNALAIBG_00004 2796 3 Skin 0.75 protein_coding synonymous_variant LOW 345C>T Ala115Ala
M0076721 CNALAIBG_00004 2873 3 Skin 0.75 protein_coding missense_variant MODERATE 422A>G Glu141Gly
M0076722 CNALAIBG_00004 2880 3 Skin 0.75 protein_coding synonymous_variant LOW 429A>G Gly143Gly
M0076723 CNALAIBG_00004 2931 3 Skin 0.75 protein_coding synonymous_variant LOW 480A>G Lys160Lys
M0076724 CNALAIBG_00004 2943 3 Skin 0.75 protein_coding synonymous_variant LOW 492T>C Ile164Ile
M0076725 CNALAIBG_00004 2968 3 Skin 0.75 protein_coding missense_variant MODERATE 517G>A Val173Ile
M0076726 CNALAIBG_00005 3234 3 Skin 0.75 protein_coding synonymous_variant LOW 519A>G Ala173Ala
M0076727 CNALAIBG_00005 3330 3 Skin 0.75 protein_coding synonymous_variant LOW 423A>G Glu141Glu
M0076728 CNALAIBG_00005 3339 3 Skin 0.75 protein_coding synonymous_variant LOW 414C>T Ser138Ser
M0076729 CNALAIBG_00005 3384 3 Skin 0.75 protein_coding synonymous_variant LOW 369C>T Cys123Cys
M0076730 CNALAIBG_00005 3405 3 Skin 0.75 protein_coding synonymous_variant LOW 348A>T Leu116Leu
M0076731 CNALAIBG_00005 3519 4 Skin 1.00 protein_coding synonymous_variant LOW 234C>T Tyr78Tyr
M0076732 CNALAIBG_00005 3567 3 Skin 0.75 protein_coding synonymous_variant LOW 186G>A Leu62Leu
M0076733 CNALAIBG_00005 3690 3 Skin 0.75 protein_coding synonymous_variant LOW 63C>T Asn21Asn
M0076734 CNALAIBG_00005 3756 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -4G>A None
M0076735 CNALAIBG_00006 3822 3 Skin 0.75 protein_coding synonymous_variant LOW 621G>T Thr207Thr
M0076736 CNALAIBG_00006 3858 3 Skin 0.75 protein_coding missense_variant MODERATE 585A>C Glu195Asp
M0076737 CNALAIBG_00006 3912 3 Skin 0.75 protein_coding synonymous_variant LOW 531C>T Asp177Asp
M0076738 CNALAIBG_00006 3941 3 Skin 0.75 protein_coding missense_variant MODERATE 502A>C Met168Leu
M0076739 CNALAIBG_00006 3996 3 Skin 0.75 protein_coding synonymous_variant LOW 447T>C Phe149Phe
M0076740 CNALAIBG_00006 4074 3 Skin 0.75 protein_coding synonymous_variant LOW 369T>C Ser123Ser
M0076741 CNALAIBG_00006 4086 3 Skin 0.75 protein_coding synonymous_variant LOW 357G>A Thr119Thr
M0076742 CNALAIBG_00006 4122 3 Skin 0.75 protein_coding synonymous_variant LOW 321G>A Glu107Glu
M0076743 CNALAIBG_00006 4175 3 Skin 0.75 protein_coding missense_variant MODERATE 268A>G Ile90Val
M0076744 CNALAIBG_00006 4176 3 Skin 0.75 protein_coding synonymous_variant LOW 267G>A Leu89Leu
M0076745 CNALAIBG_00006 4341 3 Skin 0.75 protein_coding synonymous_variant LOW 102T>C Tyr34Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
CNALAIBG_00005 PHI:123383 agrA 88.7 2.8e-123 1 238 1.0000 1.0000 rodents infective endocarditis transcriptional regulator reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CNALAIBG_00002 QKH81799.1|GH32 99.6 0 1 495 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term