Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3185
  Reference Plasmid   MET0310_bin.36__k81_258514
  Reference Plasmid Size   6033
  Reference Plasmid GC Content   0.34
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0078650 BCHFKBEL_00001 153 3 Skin 0.60 protein_coding synonymous_variant LOW 96T>A Thr32Thr
M0078651 BCHFKBEL_00001 205 3 Skin 0.60 protein_coding synonymous_variant LOW 148C>T Leu50Leu
M0078652 BCHFKBEL_00001 216 3 Skin 0.60 protein_coding synonymous_variant LOW 159C>T Leu53Leu
M0078653 BCHFKBEL_00001 219 3 Skin 0.60 protein_coding synonymous_variant LOW 162G>A Gln54Gln
M0078654 BCHFKBEL_00002 646 3 Skin 0.60 protein_coding synonymous_variant LOW 186T>C His62His
M0078655 BCHFKBEL_00002 724 4 Skin 0.80 protein_coding synonymous_variant LOW 264G>A Gly88Gly
M0078656 BCHFKBEL_00002 738 3 Skin 0.60 protein_coding missense_variant MODERATE 278A>G Gln93Arg
M0078657 BCHFKBEL_00003 1109 4 Skin 0.80 protein_coding synonymous_variant LOW 327C>T Ile109Ile
M0078658 BCHFKBEL_00004 1360 4 Skin 0.80 protein_coding synonymous_variant LOW 156G>A Gly52Gly
M0078659 BCHFKBEL_00004 1387 4 Skin 0.80 protein_coding synonymous_variant LOW 183C>T Asp61Asp
M0078660 BCHFKBEL_00004 1396 4 Skin 0.80 protein_coding synonymous_variant LOW 192T>C Ala64Ala
M0078661 BCHFKBEL_00004 1432 4 Skin 0.80 protein_coding missense_variant MODERATE 228T>A Asn76Lys
M0078662 BCHFKBEL_00004 1435 4 Skin 0.80 protein_coding synonymous_variant LOW 231C>T Thr77Thr
M0078663 BCHFKBEL_00004 1466 3 Skin 0.60 protein_coding missense_variant MODERATE 262A>G Thr88Ala
M0078664 BCHFKBEL_00004 1488 3 Skin 0.60 protein_coding stop_lost&splice_region_variant HIGH 284A>T Ter95Leuext*?
M0078665 BCHFKBEL_00005 1564 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -7C>A None
M0078666 BCHFKBEL_00005 1657 4 Skin 0.80 protein_coding synonymous_variant LOW 87C>T Cys29Cys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BCHFKBEL_00007 3.A.1.15.3 72.3 5.3e-101 1 231 0.9429 0.7428 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily