Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3190
  Reference Plasmid   MET0316_bin.10__k81_130158
  Reference Plasmid Size   26991
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0079280 IOFJMMJH_00003 3019 4 Skin 0.67 protein_coding missense_variant MODERATE 280G>A Ala94Thr
M0079281 IOFJMMJH_00003 3223 3 Skin 0.50 protein_coding missense_variant MODERATE 484G>C Val162Leu
M0079282 IOFJMMJH_00003 3294 3 Skin 0.50 protein_coding synonymous_variant LOW 555G>C Leu185Leu
M0079283 IOFJMMJH_00003 3312 3 Skin 0.50 protein_coding synonymous_variant LOW 573A>G Thr191Thr
M0079284 IOFJMMJH_00003 3324 3 Skin 0.50 protein_coding synonymous_variant LOW 585C>T Leu195Leu
M0079285 IOFJMMJH_00003 3333 3 Skin 0.50 protein_coding synonymous_variant LOW 594G>C Thr198Thr
M0079286 IOFJMMJH_00003 3601 3 Skin 0.50 protein_coding synonymous_variant LOW 862T>C Leu288Leu
M0079287 IOFJMMJH_00003 3687 3 Skin 0.50 protein_coding synonymous_variant LOW 948C>G Leu316Leu
M0079288 IOFJMMJH_00003 3690 3 Skin 0.50 protein_coding synonymous_variant LOW 951C>G Leu317Leu
M0079289 IOFJMMJH_00003 3717 3 Skin 0.50 protein_coding synonymous_variant LOW 978A>C Leu326Leu
M0079290 IOFJMMJH_00003 3718 3 Skin 0.50 protein_coding missense_variant MODERATE 979C>G Leu327Val
M0079291 IOFJMMJH_00003 3729 3 Skin 0.50 protein_coding synonymous_variant LOW 990A>C Ser330Ser
M0079292 IOFJMMJH_00003 3741 3 Skin 0.50 protein_coding synonymous_variant LOW 1002A>G Ser334Ser
M0079293 IOFJMMJH_00003 3756 3 Skin 0.50 protein_coding synonymous_variant LOW 1017C>G Leu339Leu
M0079294 IOFJMMJH_00003 3777 3 Skin 0.50 protein_coding synonymous_variant LOW 1038C>G Ala346Ala
M0079295 IOFJMMJH_00003 3807 3 Skin 0.50 protein_coding synonymous_variant LOW 1068T>C Pro356Pro
M0079296 IOFJMMJH_00003 3868 3 Skin 0.50 protein_coding missense_variant MODERATE 1129G>A Ala377Thr
M0079297 IOFJMMJH_00001 5553 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3482T>C None
M0079298 IOFJMMJH_00001 5560 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3489G>C None
M0079299 IOFJMMJH_00006 5589 3 Skin 0.50 protein_coding missense_variant MODERATE 410A>G Asp137Gly
M0079300 IOFJMMJH_00006 5680 3 Skin 0.50 protein_coding missense_variant MODERATE 319A>G Thr107Ala
M0079301 IOFJMMJH_00006 5702 3 Skin 0.50 protein_coding synonymous_variant LOW 297A>G Ala99Ala
M0079302 IOFJMMJH_00006 5707 3 Skin 0.50 protein_coding synonymous_variant LOW 292T>C Leu98Leu
M0079303 IOFJMMJH_00006 5726 3 Skin 0.50 protein_coding synonymous_variant LOW 273T>C Cys91Cys
M0079304 IOFJMMJH_00006 5984 4 Skin 0.67 protein_coding synonymous_variant LOW 15C>T Ala5Ala
M0079305 IOFJMMJH_00001 6086 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4015A>G None
M0079306 IOFJMMJH_00001 6165 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4094G>T None
M0079307 IOFJMMJH_00001 6226 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4155C>T None
M0079308 IOFJMMJH_00001 6359 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4288G>A None
M0079309 IOFJMMJH_00001 6367 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4296A>G None
M0079310 IOFJMMJH_00001 6373 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4302G>T None
M0079311 IOFJMMJH_00001 6405 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4334A>G None
M0079312 IOFJMMJH_00001 6408 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4337A>G None
M0079313 IOFJMMJH_00001 6518 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4447A>G None
M0079314 IOFJMMJH_00001 6522 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4451A>G None
M0079315 IOFJMMJH_00001 6540 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -4469T>C None
M0079316 IOFJMMJH_00007 6632 4 Skin 0.67 protein_coding synonymous_variant LOW 48A>G Ser16Ser
M0079317 IOFJMMJH_00007 6672 4 Skin 0.67 protein_coding missense_variant MODERATE 88T>C Ser30Pro
M0079318 IOFJMMJH_00007 7475 3 Skin 0.50 protein_coding synonymous_variant LOW 891G>C Ala297Ala
M0079319 IOFJMMJH_00007 7493 3 Skin 0.50 protein_coding missense_variant MODERATE 909G>C Glu303Asp
M0079320 IOFJMMJH_00007 7554 3 Skin 0.50 protein_coding missense_variant MODERATE 970C>A Arg324Ser
M0079321 IOFJMMJH_00007 7569 3 Skin 0.50 protein_coding missense_variant MODERATE 985T>A Ser329Thr
M0079322 IOFJMMJH_00007 7570 3 Skin 0.50 protein_coding missense_variant MODERATE 986C>G Ser329Cys
M0079323 IOFJMMJH_00007 7573 3 Skin 0.50 protein_coding missense_variant MODERATE 989G>A Arg330Lys
M0079324 IOFJMMJH_00007 7604 3 Skin 0.50 protein_coding synonymous_variant LOW 1020C>G Leu340Leu
M0079325 IOFJMMJH_00007 7691 3 Skin 0.50 protein_coding synonymous_variant LOW 1107A>G Glu369Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term