Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3191
  Reference Plasmid   MET0316_bin.10__k81_27502
  Reference Plasmid Size   25377
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0079326 JNCPDJCN_00014 16475 3 Skin 0.50 protein_coding missense_variant MODERATE 50C>A Ala17Glu
M0079327 JNCPDJCN_00014 16498 3 Skin 0.50 protein_coding synonymous_variant LOW 27T>C Leu9Leu
M0079328 JNCPDJCN_00014 16516 3 Skin 0.50 protein_coding synonymous_variant LOW 9G>A Ala3Ala
M0079329 JNCPDJCN_00009 16546 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4359C>T None
M0079330 JNCPDJCN_00015 16563 3 Skin 0.50 protein_coding missense_variant MODERATE 225C>G His75Gln
M0079331 JNCPDJCN_00015 16658 3 Skin 0.50 protein_coding missense_variant MODERATE 130A>G Asn44Asp
M0079332 JNCPDJCN_00015 16782 3 Skin 0.50 protein_coding synonymous_variant LOW 6A>G Lys2Lys
M0079333 JNCPDJCN_00009 16827 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4640G>A None
M0079334 JNCPDJCN_00009 16847 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4660C>T None
M0079335 JNCPDJCN_00009 16849 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4662T>C None
M0079336 JNCPDJCN_00009 16886 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4699A>G None
M0079337 JNCPDJCN_00009 16947 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4760C>A None
M0079338 JNCPDJCN_00009 16957 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4770G>T None
M0079339 JNCPDJCN_00009 16967 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4780G>C None
M0079340 JNCPDJCN_00009 16969 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4782T>C None
M0079341 JNCPDJCN_00016 17003 3 Skin 0.50 protein_coding synonymous_variant LOW 27A>C Thr9Thr
M0079342 JNCPDJCN_00016 17225 3 Skin 0.50 protein_coding synonymous_variant LOW 249T>C Asp83Asp
M0079343 JNCPDJCN_00016 17319 3 Skin 0.50 protein_coding missense_variant MODERATE 343T>C Cys115Arg
M0079344 JNCPDJCN_00016 17361 3 Skin 0.50 protein_coding missense_variant MODERATE 385T>C Trp129Arg
M0079345 JNCPDJCN_00016 17382 3 Skin 0.50 protein_coding missense_variant MODERATE 406A>G Thr136Ala
M0079346 JNCPDJCN_00012 17402 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2325C>G None
M0079347 JNCPDJCN_00012 17420 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2343C>T None
M0079348 JNCPDJCN_00012 17435 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2358T>C None
M0079349 JNCPDJCN_00017 17837 3 Skin 0.50 protein_coding synonymous_variant LOW 354G>A Gly118Gly
M0079350 JNCPDJCN_00017 17839 3 Skin 0.50 protein_coding missense_variant MODERATE 356T>C Val119Ala
M0079351 JNCPDJCN_00017 17906 3 Skin 0.50 protein_coding synonymous_variant LOW 423T>C His141His
M0079352 JNCPDJCN_00017 18032 3 Skin 0.50 protein_coding synonymous_variant LOW 549T>C His183His
M0079353 JNCPDJCN_00017 18257 3 Skin 0.50 protein_coding synonymous_variant LOW 774C>T Asp258Asp
M0079354 JNCPDJCN_00017 18345 3 Skin 0.50 protein_coding missense_variant MODERATE 862A>G Ser288Gly
M0079355 JNCPDJCN_00017 19122 3 Skin 0.50 protein_coding missense_variant MODERATE 1639C>G Gln547Glu
M0079356 JNCPDJCN_00017 19163 3 Skin 0.50 protein_coding synonymous_variant LOW 1680C>T Asp560Asp
M0079357 JNCPDJCN_00017 19175 3 Skin 0.50 protein_coding synonymous_variant LOW 1692T>C Arg564Arg
M0079358 JNCPDJCN_00017 19253 3 Skin 0.50 protein_coding synonymous_variant LOW 1770T>C Thr590Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term