Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3193
  Reference Plasmid   MET0316_bin.10__k81_85622
  Reference Plasmid Size   23533
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0079384 BFANAMOL_00010 11504 3 Skin 0.75 protein_coding missense_variant MODERATE 127A>G Lys43Glu
M0079385 BFANAMOL_00011 11767 3 Skin 0.75 protein_coding missense_variant MODERATE 976A>G Thr326Ala
M0079386 BFANAMOL_00011 11774 3 Skin 0.75 protein_coding synonymous_variant LOW 969G>C Ala323Ala
M0079387 BFANAMOL_00011 11777 3 Skin 0.75 protein_coding synonymous_variant LOW 966T>C Gly322Gly
M0079388 BFANAMOL_00011 11830 3 Skin 0.75 protein_coding missense_variant MODERATE 913G>T Val305Leu
M0079389 BFANAMOL_00011 12015 3 Skin 0.75 protein_coding missense_variant MODERATE 728G>A Arg243His
M0079390 BFANAMOL_00011 12022 3 Skin 0.75 protein_coding missense_variant MODERATE 721T>A Ser241Thr
M0079391 BFANAMOL_00011 12024 3 Skin 0.75 protein_coding missense_variant MODERATE 719G>A Ser240Asn
M0079392 BFANAMOL_00011 12026 3 Skin 0.75 protein_coding synonymous_variant LOW 717G>C Gly239Gly
M0079393 BFANAMOL_00011 12031 3 Skin 0.75 protein_coding missense_variant MODERATE 712G>A Ala238Thr
M0079394 BFANAMOL_00011 12035 3 Skin 0.75 protein_coding synonymous_variant LOW 708T>C Ala236Ala
M0079395 BFANAMOL_00011 12038 3 Skin 0.75 protein_coding synonymous_variant LOW 705T>C Asp235Asp
M0079396 BFANAMOL_00011 12041 3 Skin 0.75 protein_coding synonymous_variant LOW 702T>G Pro234Pro
M0079397 BFANAMOL_00011 12044 3 Skin 0.75 protein_coding synonymous_variant LOW 699T>C Ala233Ala
M0079398 BFANAMOL_00011 12125 3 Skin 0.75 protein_coding synonymous_variant LOW 618G>A Arg206Arg
M0079399 BFANAMOL_00011 12299 3 Skin 0.75 protein_coding synonymous_variant LOW 444A>G Gly148Gly
M0079400 BFANAMOL_00011 12662 3 Skin 0.75 protein_coding synonymous_variant LOW 81G>C Ala27Ala
M0079401 BFANAMOL_00011 12689 3 Skin 0.75 protein_coding synonymous_variant LOW 54A>G Arg18Arg
M0079402 BFANAMOL_00011 12705 3 Skin 0.75 protein_coding missense_variant MODERATE 38A>G Asp13Gly
M0079403 BFANAMOL_00011 12712 3 Skin 0.75 protein_coding missense_variant MODERATE 31C>T Pro11Ser
M0079404 BFANAMOL_00011 12736 3 Skin 0.75 protein_coding missense_variant MODERATE 7C>G Pro3Ala
M0079405 BFANAMOL_00012 12770 3 Skin 0.75 protein_coding missense_variant MODERATE 911T>C Val304Ala
M0079406 BFANAMOL_00012 12988 3 Skin 0.75 protein_coding synonymous_variant LOW 693T>C Arg231Arg
M0079407 BFANAMOL_00012 13008 3 Skin 0.75 protein_coding synonymous_variant LOW 673T>C Leu225Leu
M0079408 BFANAMOL_00012 13144 3 Skin 0.75 protein_coding synonymous_variant LOW 537C>G Val179Val
M0079409 BFANAMOL_00012 13207 3 Skin 0.75 protein_coding synonymous_variant LOW 474T>C Cys158Cys
M0079410 BFANAMOL_00012 13405 3 Skin 0.75 protein_coding synonymous_variant LOW 276A>G Leu92Leu
M0079411 BFANAMOL_00012 13432 3 Skin 0.75 protein_coding synonymous_variant LOW 249C>G Thr83Thr
M0079412 BFANAMOL_00012 13486 3 Skin 0.75 protein_coding synonymous_variant LOW 195A>C Gly65Gly
M0079413 BFANAMOL_00012 13489 3 Skin 0.75 protein_coding synonymous_variant LOW 192G>C Ala64Ala
M0079414 BFANAMOL_00012 13503 3 Skin 0.75 protein_coding synonymous_variant LOW 178T>C Leu60Leu
M0079415 BFANAMOL_00012 13504 3 Skin 0.75 protein_coding synonymous_variant LOW 177A>G Arg59Arg
M0079416 BFANAMOL_00012 13528 3 Skin 0.75 protein_coding synonymous_variant LOW 153G>C Ala51Ala
M0079417 BFANAMOL_00012 13573 3 Skin 0.75 protein_coding synonymous_variant LOW 108T>C Ile36Ile
M0079418 BFANAMOL_00012 13574 3 Skin 0.75 protein_coding missense_variant MODERATE 107T>C Ile36Thr
M0079419 BFANAMOL_00013 14010 3 Skin 0.75 protein_coding synonymous_variant LOW 873A>G Arg291Arg
M0079420 BFANAMOL_00013 14100 3 Skin 0.75 protein_coding synonymous_variant LOW 783T>C Gly261Gly
M0079421 BFANAMOL_00013 14414 3 Skin 0.75 protein_coding missense_variant MODERATE 469A>G Ser157Gly
M0079422 BFANAMOL_00013 14778 3 Skin 0.75 protein_coding synonymous_variant LOW 105C>G Ala35Ala
M0079423 BFANAMOL_00013 14868 3 Skin 0.75 protein_coding synonymous_variant LOW 15A>G Ala5Ala
M0079424 BFANAMOL_00014 14932 3 Skin 0.75 protein_coding synonymous_variant LOW 198T>C Ala66Ala
M0079425 BFANAMOL_00014 14956 3 Skin 0.75 protein_coding synonymous_variant LOW 174T>C Phe58Phe
M0079426 BFANAMOL_00015 15320 3 Skin 0.75 protein_coding synonymous_variant LOW 348T>C Ala116Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BFANAMOL_00010 QBJ22253.1|GH2 97.6 0 1 922 1 0.9968
BFANAMOL_00018 QBJ22259.1|GT4 100 2.63e-301 1 419 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term