Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3195
  Reference Plasmid   MET0332_bin.9__k81_49882
  Reference Plasmid Size   2678
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0079432 BOLDIPKF_00001 292 3 Skin 0.38 protein_coding missense_variant MODERATE 217G>A Asp73Asn
M0079433 BOLDIPKF_00001 306 4 Skin 0.50 protein_coding synonymous_variant LOW 231C>T His77His
M0079434 BOLDIPKF_00002 468 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -317A>C None
M0079435 BOLDIPKF_00002 471 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -314C>T None
M0079436 BOLDIPKF_00002 480 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -305A>T None
M0079437 BOLDIPKF_00002 485 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -300A>G None
M0079438 BOLDIPKF_00002 526 6 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -259G>A None
M0079439 BOLDIPKF_00002 533 6 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -252T>C None
M0079440 BOLDIPKF_00002 546 6 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -239G>C None
M0079441 BOLDIPKF_00002 548 6 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -237T>C None
M0079442 BOLDIPKF_00002 552 6 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -233G>A None
M0079443 BOLDIPKF_00002 555 6 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -230T>C None
M0079444 BOLDIPKF_00002 578 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -207T>C None
M0079445 BOLDIPKF_00002 592 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -193C>T None
M0079446 BOLDIPKF_00002 594 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -191G>A None
M0079447 BOLDIPKF_00002 603 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -182C>T None
M0079448 BOLDIPKF_00002 818 3 Skin 0.38 protein_coding missense_variant MODERATE 34T>G Cys12Gly
M0079449 BOLDIPKF_00002 879 3 Skin 0.38 protein_coding missense_variant MODERATE 95G>A Arg32His
M0079450 BOLDIPKF_00002 904 3 Skin 0.38 protein_coding synonymous_variant LOW 120G>A Gly40Gly
M0079451 BOLDIPKF_00002 964 3 Skin 0.38 protein_coding synonymous_variant LOW 180T>A Pro60Pro
M0079452 BOLDIPKF_00002 1054 6 Skin 0.75 protein_coding synonymous_variant LOW 270A>G Gln90Gln
M0079453 BOLDIPKF_00002 1069 4 Skin 0.50 protein_coding synonymous_variant LOW 285T>C Arg95Arg
M0079454 BOLDIPKF_00002 1124 3 Skin 0.38 protein_coding missense_variant MODERATE 340C>T Arg114Cys
M0079455 BOLDIPKF_00002 1159 3 Skin 0.38 protein_coding synonymous_variant LOW 375C>T Val125Val
M0079456 BOLDIPKF_00002 1198 3 Skin 0.38 protein_coding synonymous_variant LOW 414C>T Gly138Gly
M0079457 BOLDIPKF_00002 1199 3 Skin 0.38 protein_coding missense_variant MODERATE 415G>A Gly139Arg
M0079458 BOLDIPKF_00001 1210 3 Skin 0.38 protein_coding downstream_gene_variant MODIFIER *784C>G None
M0079459 BOLDIPKF_00003 1350 4 Skin 0.50 protein_coding synonymous_variant LOW 399C>A Ala133Ala
M0079460 BOLDIPKF_00003 1356 4 Skin 0.50 protein_coding synonymous_variant LOW 393T>C Arg131Arg
M0079461 BOLDIPKF_00003 1359 4 Skin 0.50 protein_coding synonymous_variant LOW 390A>C Val130Val
M0079462 BOLDIPKF_00003 1365 4 Skin 0.50 protein_coding synonymous_variant LOW 384G>A Leu128Leu
M0079463 BOLDIPKF_00003 1377 4 Skin 0.50 protein_coding synonymous_variant LOW 372C>T Ala124Ala
M0079464 BOLDIPKF_00003 1434 5 Skin 0.63 protein_coding synonymous_variant LOW 315C>T His105His
M0079465 BOLDIPKF_00003 1458 5 Skin 0.63 protein_coding synonymous_variant LOW 291T>C Arg97Arg
M0079466 BOLDIPKF_00003 1464 5 Skin 0.63 protein_coding synonymous_variant LOW 285A>G Leu95Leu
M0079467 BOLDIPKF_00003 1466 5 Skin 0.63 protein_coding synonymous_variant LOW 283T>C Leu95Leu
M0079468 BOLDIPKF_00003 1470 3 Skin 0.38 protein_coding synonymous_variant LOW 279T>C Thr93Thr
M0079469 BOLDIPKF_00003 1497 4 Skin 0.50 protein_coding synonymous_variant LOW 252A>G Val84Val
M0079470 BOLDIPKF_00003 1506 5 Skin 0.63 protein_coding synonymous_variant LOW 243T>C His81His
M0079471 BOLDIPKF_00003 1509 5 Skin 0.63 protein_coding synonymous_variant LOW 240T>C Asn80Asn
M0079472 BOLDIPKF_00003 1521 5 Skin 0.63 protein_coding synonymous_variant LOW 228C>T Tyr76Tyr
M0079473 BOLDIPKF_00003 1539 5 Skin 0.63 protein_coding synonymous_variant LOW 210G>T Gly70Gly
M0079474 BOLDIPKF_00003 1542 5 Skin 0.63 protein_coding missense_variant MODERATE 207G>T Leu69Phe
M0079475 BOLDIPKF_00003 1544 5 Skin 0.63 protein_coding synonymous_variant LOW 205T>C Leu69Leu
M0079476 BOLDIPKF_00003 1545 5 Skin 0.63 protein_coding synonymous_variant LOW 204G>A Glu68Glu
M0079477 BOLDIPKF_00003 1557 5 Skin 0.63 protein_coding synonymous_variant LOW 192T>C Phe64Phe
M0079478 BOLDIPKF_00003 1575 3 Skin 0.38 protein_coding synonymous_variant LOW 174C>T Asp58Asp
M0079479 BOLDIPKF_00003 1750 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -2C>T None
M0079480 BOLDIPKF_00003 1865 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -117T>C None
M0079481 BOLDIPKF_00004 1905 3 Skin 0.38 protein_coding synonymous_variant LOW 747C>G Thr249Thr
M0079482 BOLDIPKF_00004 2024 5 Skin 0.63 protein_coding missense_variant MODERATE 628C>A His210Asn
M0079483 BOLDIPKF_00004 2040 5 Skin 0.63 protein_coding synonymous_variant LOW 612G>A Ser204Ser
M0079484 BOLDIPKF_00004 2067 4 Skin 0.50 protein_coding synonymous_variant LOW 585A>G Lys195Lys
M0079485 BOLDIPKF_00004 2205 5 Skin 0.63 protein_coding synonymous_variant LOW 447T>G Leu149Leu
M0079486 BOLDIPKF_00004 2259 5 Skin 0.63 protein_coding synonymous_variant LOW 393T>C Arg131Arg
M0079487 BOLDIPKF_00004 2270 3 Skin 0.38 protein_coding missense_variant MODERATE 382G>A Ala128Thr
M0079488 BOLDIPKF_00004 2421 4 Skin 0.50 protein_coding synonymous_variant LOW 231A>G Gly77Gly
M0079489 BOLDIPKF_00004 2430 4 Skin 0.50 protein_coding synonymous_variant LOW 222C>T Cys74Cys
M0079490 BOLDIPKF_00004 2523 3 Skin 0.38 protein_coding synonymous_variant LOW 129A>G Lys43Lys
M0079491 BOLDIPKF_00004 2526 3 Skin 0.38 protein_coding synonymous_variant LOW 126T>G Val42Val
M0079492 BOLDIPKF_00004 2541 3 Skin 0.38 protein_coding synonymous_variant LOW 111G>T Thr37Thr
M0079493 BOLDIPKF_00004 2622 3 Skin 0.38 protein_coding synonymous_variant LOW 30G>T Leu10Leu
M0079494 BOLDIPKF_00004 2634 3 Skin 0.38 protein_coding synonymous_variant LOW 18T>C Arg6Arg
M0079495 BOLDIPKF_00001 168 3 Skin 0.38 protein_coding synonymous_variant LOW 93T>G Arg31Arg
M0079496 BOLDIPKF_00001 171 3 Skin 0.38 protein_coding synonymous_variant LOW 96C>T Gly32Gly
M0079497 BOLDIPKF_00001 174 4 Skin 0.50 protein_coding synonymous_variant LOW 99C>A Val33Val
M0079498 BOLDIPKF_00002 532 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -253T>C None
M0079499 BOLDIPKF_00002 1033 3 Skin 0.38 protein_coding synonymous_variant LOW 249C>T Pro83Pro
M0079500 BOLDIPKF_00002 1034 3 Skin 0.38 protein_coding missense_variant MODERATE 250G>A Gly84Ser
M0079501 BOLDIPKF_00001 126 3 Skin 0.38 protein_coding synonymous_variant LOW 51G>A Ser17Ser
M0079502 BOLDIPKF_00001 309 3 Skin 0.38 protein_coding synonymous_variant LOW 234A>G Val78Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term