Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3198
  Reference Plasmid   MET0350_bin.5__k81_10587
  Reference Plasmid Size   2135
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0079659 KLMFLDIH_00001 133 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -726G>A None
M0079660 KLMFLDIH_00001 275 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -584C>T None
M0079661 KLMFLDIH_00001 409 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -450A>G None
M0079662 KLMFLDIH_00001 454 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -405A>G None
M0079663 KLMFLDIH_00001 475 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -384T>A None
M0079664 KLMFLDIH_00001 537 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -322G>A None
M0079665 KLMFLDIH_00001 563 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -296A>C None
M0079666 KLMFLDIH_00001 586 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -273T>C None
M0079667 KLMFLDIH_00001 590 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -269C>T None
M0079668 KLMFLDIH_00002 1414 3 Skin 0.50 protein_coding missense_variant MODERATE 194G>A Gly65Asp
M0079669 KLMFLDIH_00002 1415 3 Skin 0.50 protein_coding synonymous_variant LOW 195C>T Gly65Gly
M0079670 KLMFLDIH_00002 1421 3 Skin 0.50 protein_coding synonymous_variant LOW 201A>G Val67Val
M0079671 KLMFLDIH_00002 1427 3 Skin 0.50 protein_coding synonymous_variant LOW 207A>T Pro69Pro
M0079672 KLMFLDIH_00002 1430 3 Skin 0.50 protein_coding synonymous_variant LOW 210G>A Glu70Glu
M0079673 KLMFLDIH_00002 1599 3 Skin 0.50 protein_coding missense_variant MODERATE 379A>G Ile127Val
M0079674 KLMFLDIH_00002 1784 3 Skin 0.50 protein_coding missense_variant MODERATE 564T>G Asp188Glu
M0079675 KLMFLDIH_00001 2085 3 Skin 0.50 protein_coding downstream_gene_variant MODIFIER *846G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term