Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3200
  Reference Plasmid   MET0353_bin.39__k81_84063
  Reference Plasmid Size   134330
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0150555 FNAMEEHD_00108 115912 3 Gut 0.43 protein_coding synonymous_variant LOW 264A>G Gln88Gln
M0150556 FNAMEEHD_00111 117386 3 Gut 0.43 protein_coding missense_variant MODERATE 118G>A Ala40Thr
M0150557 FNAMEEHD_00111 117455 3 Gut 0.43 protein_coding missense_variant MODERATE 187A>G Ile63Val
M0150558 FNAMEEHD_00111 117494 3 Gut 0.43 protein_coding missense_variant MODERATE 226A>G Met76Val
M0150559 FNAMEEHD_00112 117681 3 Gut 0.43 protein_coding missense_variant MODERATE 11T>A Ile4Lys
M0150560 FNAMEEHD_00112 117694 3 Gut 0.43 protein_coding synonymous_variant LOW 24A>G Lys8Lys
M0150561 FNAMEEHD_00112 117712 3 Gut 0.43 protein_coding synonymous_variant LOW 42G>A Ser14Ser
M0150562 FNAMEEHD_00112 117738 3 Gut 0.43 protein_coding missense_variant MODERATE 68C>T Ala23Val
M0150563 FNAMEEHD_00112 117742 3 Gut 0.43 protein_coding synonymous_variant LOW 72T>C Phe24Phe
M0150564 FNAMEEHD_00112 117743 3 Gut 0.43 protein_coding missense_variant MODERATE 73C>A Leu25Ile
M0150565 FNAMEEHD_00112 117751 3 Gut 0.43 protein_coding synonymous_variant LOW 81T>A Ile27Ile
M0150566 FNAMEEHD_00112 117772 3 Gut 0.43 protein_coding synonymous_variant LOW 102A>G Val34Val
M0150567 FNAMEEHD_00112 117784 3 Gut 0.43 protein_coding synonymous_variant LOW 114T>C Asn38Asn
M0150568 FNAMEEHD_00112 117919 3 Gut 0.43 protein_coding synonymous_variant LOW 249T>G Leu83Leu
M0150569 FNAMEEHD_00112 117931 3 Gut 0.43 protein_coding synonymous_variant LOW 261G>T Val87Val
M0150570 FNAMEEHD_00112 117982 3 Gut 0.43 protein_coding synonymous_variant LOW 312A>T Val104Val
M0150571 FNAMEEHD_00112 118009 3 Gut 0.43 protein_coding synonymous_variant LOW 339T>G Leu113Leu
M0150572 FNAMEEHD_00112 118237 3 Gut 0.43 protein_coding synonymous_variant LOW 567C>T Asn189Asn
M0150573 FNAMEEHD_00112 118271 3 Gut 0.43 protein_coding missense_variant MODERATE 601G>A Glu201Lys
M0150574 FNAMEEHD_00112 118274 3 Gut 0.43 protein_coding synonymous_variant LOW 604T>C Leu202Leu
M0150575 FNAMEEHD_00112 118279 3 Gut 0.43 protein_coding synonymous_variant LOW 609C>T Ser203Ser
M0150576 FNAMEEHD_00112 118513 3 Gut 0.43 protein_coding synonymous_variant LOW 843C>T Gly281Gly
M0150577 FNAMEEHD_00112 118516 3 Gut 0.43 protein_coding synonymous_variant LOW 846C>A Gly282Gly
M0150578 FNAMEEHD_00112 118543 3 Gut 0.43 protein_coding synonymous_variant LOW 873C>T Thr291Thr
M0150579 FNAMEEHD_00112 118580 3 Gut 0.43 protein_coding missense_variant MODERATE 910C>A Gln304Lys
M0150580 FNAMEEHD_00112 118672 3 Gut 0.43 protein_coding synonymous_variant LOW 1002T>G Val334Val
M0150581 FNAMEEHD_00112 118721 3 Gut 0.43 protein_coding missense_variant MODERATE 1051G>A Val351Ile
M0150582 FNAMEEHD_00112 118726 3 Gut 0.43 protein_coding synonymous_variant LOW 1056C>T Ile352Ile
M0150583 FNAMEEHD_00112 118733 3 Gut 0.43 protein_coding synonymous_variant LOW 1063A>C Arg355Arg
M0150584 FNAMEEHD_00112 119583 3 Gut 0.43 protein_coding missense_variant MODERATE 1913C>G Thr638Arg
M0150585 FNAMEEHD_00112 119639 3 Gut 0.43 protein_coding missense_variant MODERATE 1969T>C Ser657Pro
M0150586 FNAMEEHD_00113 120201 3 Gut 0.43 protein_coding missense_variant MODERATE 329G>C Gly110Ala
M0150587 FNAMEEHD_00114 120268 3 Gut 0.43 protein_coding missense_variant MODERATE 71A>G Tyr24Cys
M0150588 FNAMEEHD_00114 120419 3 Gut 0.43 protein_coding synonymous_variant LOW 222A>T Ser74Ser
M0150589 FNAMEEHD_00114 121061 3 Gut 0.43 protein_coding synonymous_variant LOW 864A>T Ala288Ala
M0150590 FNAMEEHD_00114 121757 3 Gut 0.43 protein_coding synonymous_variant LOW 1560T>C Phe520Phe
M0150591 FNAMEEHD_00114 121793 3 Gut 0.43 protein_coding synonymous_variant LOW 1596C>T Ser532Ser
M0150592 FNAMEEHD_00114 121862 3 Gut 0.43 protein_coding synonymous_variant LOW 1665C>T Asn555Asn
M0150593 FNAMEEHD_00114 121864 3 Gut 0.43 protein_coding missense_variant MODERATE 1667A>G Asn556Ser
M0150594 FNAMEEHD_00114 121985 3 Gut 0.43 protein_coding synonymous_variant LOW 1788A>G Val596Val
M0150595 FNAMEEHD_00114 122276 3 Gut 0.43 protein_coding synonymous_variant LOW 2079T>A Ser693Ser
M0150596 FNAMEEHD_00114 122348 3 Gut 0.43 protein_coding synonymous_variant LOW 2151T>C Leu717Leu
M0150597 FNAMEEHD_00114 122600 3 Gut 0.43 protein_coding synonymous_variant LOW 2403T>C His801His
M0150598 FNAMEEHD_00114 122693 3 Gut 0.43 protein_coding synonymous_variant LOW 2496A>G Gly832Gly
M0150599 FNAMEEHD_00114 122714 3 Gut 0.43 protein_coding synonymous_variant LOW 2517T>C Asp839Asp
M0150600 FNAMEEHD_00114 122780 3 Gut 0.43 protein_coding synonymous_variant LOW 2583G>A Lys861Lys
M0150601 FNAMEEHD_00115 122806 3 Gut 0.43 protein_coding synonymous_variant LOW 12C>T Ala4Ala
M0150602 FNAMEEHD_00115 122881 3 Gut 0.43 protein_coding missense_variant MODERATE 87A>T Lys29Asn
M0150603 FNAMEEHD_00115 123001 3 Gut 0.43 protein_coding synonymous_variant LOW 207G>A Thr69Thr
M0150604 FNAMEEHD_00115 123078 3 Gut 0.43 protein_coding missense_variant MODERATE 284G>A Gly95Asp
M0150605 FNAMEEHD_00115 123122 3 Gut 0.43 protein_coding missense_variant MODERATE 328A>G Asn110Asp
M0150606 FNAMEEHD_00115 123796 3 Gut 0.43 protein_coding synonymous_variant LOW 1002G>T Thr334Thr
M0150607 FNAMEEHD_00115 123832 3 Gut 0.43 protein_coding synonymous_variant LOW 1038C>A Ile346Ile
M0150608 FNAMEEHD_00115 123835 3 Gut 0.43 protein_coding synonymous_variant LOW 1041T>C Ile347Ile
M0150609 FNAMEEHD_00115 123841 3 Gut 0.43 protein_coding synonymous_variant LOW 1047A>G Glu349Glu
M0150610 FNAMEEHD_00115 123877 3 Gut 0.43 protein_coding synonymous_variant LOW 1083C>T Ser361Ser
M0150611 FNAMEEHD_00117 124674 3 Gut 0.43 protein_coding synonymous_variant LOW 39G>A Lys13Lys
M0150612 FNAMEEHD_00118 125066 3 Gut 0.43 protein_coding missense_variant MODERATE 121G>A Ala41Thr
M0150613 FNAMEEHD_00118 125092 3 Gut 0.43 protein_coding synonymous_variant LOW 147G>A Arg49Arg
M0150614 FNAMEEHD_00118 125099 3 Gut 0.43 protein_coding missense_variant MODERATE 154C>T Pro52Ser
M0150615 FNAMEEHD_00118 125125 3 Gut 0.43 protein_coding synonymous_variant LOW 180G>A Lys60Lys
M0150616 FNAMEEHD_00118 125127 3 Gut 0.43 protein_coding missense_variant MODERATE 182G>A Gly61Glu
M0150617 FNAMEEHD_00118 125153 3 Gut 0.43 protein_coding missense_variant MODERATE 208G>A Ala70Thr
M0150618 FNAMEEHD_00118 125183 3 Gut 0.43 protein_coding missense_variant MODERATE 238C>A Leu80Ile
M0150619 FNAMEEHD_00120 125601 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -41G>A None
M0150620 FNAMEEHD_00120 125905 3 Gut 0.43 protein_coding synonymous_variant LOW 264A>C Ala88Ala
M0150621 FNAMEEHD_00120 125949 3 Gut 0.43 protein_coding missense_variant MODERATE 308A>T Tyr103Phe
M0150622 FNAMEEHD_00121 126567 3 Gut 0.43 protein_coding synonymous_variant LOW 558A>G Lys186Lys
M0150623 FNAMEEHD_00121 126595 3 Gut 0.43 protein_coding missense_variant MODERATE 586A>C Ile196Leu
M0150624 FNAMEEHD_00121 126612 3 Gut 0.43 protein_coding synonymous_variant LOW 603A>C Ser201Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FNAMEEHD_00008 CCO06137.1|GH36 98.6 0 1 703 1 1
FNAMEEHD_00063 CCO06082.1|GH5_4 96.9 7.2e-279 1 384 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term