Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3205
  Reference Plasmid   MET0354_bin.5__k81_62465
  Reference Plasmid Size   2505
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0079739 NIJPBKJM_00001 69 4 Skin 0.67 protein_coding synonymous_variant LOW 888T>C Ile296Ile
M0079740 NIJPBKJM_00001 129 6 Skin 1.00 protein_coding synonymous_variant LOW 828T>G Ala276Ala
M0079741 NIJPBKJM_00001 165 6 Skin 1.00 protein_coding synonymous_variant LOW 792T>A Thr264Thr
M0079742 NIJPBKJM_00001 174 6 Skin 1.00 protein_coding synonymous_variant LOW 783A>T Thr261Thr
M0079743 NIJPBKJM_00001 210 4 Skin 0.67 protein_coding synonymous_variant LOW 747T>C Val249Val
M0079744 NIJPBKJM_00001 216 3 Skin 0.50 protein_coding synonymous_variant LOW 741A>T Ala247Ala
M0079745 NIJPBKJM_00001 327 4 Skin 0.67 protein_coding synonymous_variant LOW 630T>C Ile210Ile
M0079746 NIJPBKJM_00001 531 3 Skin 0.50 protein_coding synonymous_variant LOW 426T>C Tyr142Tyr
M0079747 NIJPBKJM_00001 645 3 Skin 0.50 protein_coding synonymous_variant LOW 312C>T Phe104Phe
M0079748 NIJPBKJM_00001 738 5 Skin 0.83 protein_coding synonymous_variant LOW 219C>T Ile73Ile
M0079749 NIJPBKJM_00001 756 5 Skin 0.83 protein_coding synonymous_variant LOW 201A>C Val67Val
M0079750 NIJPBKJM_00001 771 5 Skin 0.83 protein_coding synonymous_variant LOW 186C>T Ile62Ile
M0079751 NIJPBKJM_00001 843 6 Skin 1.00 protein_coding synonymous_variant LOW 114T>C Arg38Arg
M0079752 NIJPBKJM_00001 944 5 Skin 0.83 protein_coding missense_variant MODERATE 13C>T Leu5Phe
M0079753 NIJPBKJM_00002 1090 6 Skin 1.00 protein_coding synonymous_variant LOW 618T>C Arg206Arg
M0079754 NIJPBKJM_00002 1096 4 Skin 0.67 protein_coding synonymous_variant LOW 612C>T Phe204Phe
M0079755 NIJPBKJM_00002 1105 4 Skin 0.67 protein_coding synonymous_variant LOW 603T>C Ile201Ile
M0079756 NIJPBKJM_00002 1111 4 Skin 0.67 protein_coding synonymous_variant LOW 597A>C Ala199Ala
M0079757 NIJPBKJM_00002 1119 4 Skin 0.67 protein_coding missense_variant MODERATE 589A>G Ile197Val
M0079758 NIJPBKJM_00002 1156 3 Skin 0.50 protein_coding synonymous_variant LOW 552G>A Glu184Glu
M0079759 NIJPBKJM_00002 1255 6 Skin 1.00 protein_coding synonymous_variant LOW 453G>A Ala151Ala
M0079760 NIJPBKJM_00002 1267 5 Skin 0.83 protein_coding synonymous_variant LOW 441A>G Val147Val
M0079761 NIJPBKJM_00002 1273 3 Skin 0.50 protein_coding synonymous_variant LOW 435T>C Arg145Arg
M0079762 NIJPBKJM_00002 1306 6 Skin 1.00 protein_coding synonymous_variant LOW 402C>T Arg134Arg
M0079763 NIJPBKJM_00002 1309 4 Skin 0.67 protein_coding synonymous_variant LOW 399T>C Gly133Gly
M0079764 NIJPBKJM_00002 1342 4 Skin 0.67 protein_coding synonymous_variant LOW 366C>T Ile122Ile
M0079765 NIJPBKJM_00002 1345 4 Skin 0.67 protein_coding synonymous_variant LOW 363A>G Leu121Leu
M0079766 NIJPBKJM_00002 1360 4 Skin 0.67 protein_coding synonymous_variant LOW 348C>T Ala116Ala
M0079767 NIJPBKJM_00002 1372 3 Skin 0.50 protein_coding synonymous_variant LOW 336T>C Ser112Ser
M0079768 NIJPBKJM_00002 1384 4 Skin 0.67 protein_coding synonymous_variant LOW 324T>C Gly108Gly
M0079769 NIJPBKJM_00002 1390 4 Skin 0.67 protein_coding synonymous_variant LOW 318T>C Ala106Ala
M0079770 NIJPBKJM_00002 1396 4 Skin 0.67 protein_coding synonymous_variant LOW 312A>T Thr104Thr
M0079771 NIJPBKJM_00002 1405 4 Skin 0.67 protein_coding synonymous_variant LOW 303C>T Arg101Arg
M0079772 NIJPBKJM_00002 1417 4 Skin 0.67 protein_coding synonymous_variant LOW 291T>C Tyr97Tyr
M0079773 NIJPBKJM_00002 1435 4 Skin 0.67 protein_coding synonymous_variant LOW 273G>T Gly91Gly
M0079774 NIJPBKJM_00002 1441 3 Skin 0.50 protein_coding synonymous_variant LOW 267T>G Thr89Thr
M0079775 NIJPBKJM_00002 1486 4 Skin 0.67 protein_coding synonymous_variant LOW 222A>G Leu74Leu
M0079776 NIJPBKJM_00002 1507 5 Skin 0.83 protein_coding synonymous_variant LOW 201C>T Gly67Gly
M0079777 NIJPBKJM_00002 1567 4 Skin 0.67 protein_coding synonymous_variant LOW 141G>A Gly47Gly
M0079778 NIJPBKJM_00002 1582 5 Skin 0.83 protein_coding synonymous_variant LOW 126T>C Ile42Ile
M0079779 NIJPBKJM_00002 1588 5 Skin 0.83 protein_coding synonymous_variant LOW 120T>C Asn40Asn
M0079780 NIJPBKJM_00002 1591 4 Skin 0.67 protein_coding synonymous_variant LOW 117C>T Ile39Ile
M0079781 NIJPBKJM_00002 1624 4 Skin 0.67 protein_coding synonymous_variant LOW 84T>C Gly28Gly
M0079782 NIJPBKJM_00002 1660 5 Skin 0.83 protein_coding synonymous_variant LOW 48A>G Leu16Leu
M0079783 NIJPBKJM_00002 1666 5 Skin 0.83 protein_coding synonymous_variant LOW 42A>G Leu14Leu
M0079784 NIJPBKJM_00002 1693 4 Skin 0.67 protein_coding synonymous_variant LOW 15A>T Ser5Ser
M0079785 NIJPBKJM_00003 1985 6 Skin 1.00 protein_coding synonymous_variant LOW 417T>G Thr139Thr
M0079786 NIJPBKJM_00003 1991 6 Skin 1.00 protein_coding synonymous_variant LOW 411A>G Gly137Gly
M0079787 NIJPBKJM_00003 2138 5 Skin 0.83 protein_coding synonymous_variant LOW 264A>G Thr88Thr
M0079788 NIJPBKJM_00003 2174 5 Skin 0.83 protein_coding synonymous_variant LOW 228A>G Thr76Thr
M0079789 NIJPBKJM_00003 2258 6 Skin 1.00 protein_coding synonymous_variant LOW 144G>A Glu48Glu
M0079790 NIJPBKJM_00003 2267 4 Skin 0.67 protein_coding synonymous_variant LOW 135A>G Glu45Glu
M0079791 NIJPBKJM_00003 2297 6 Skin 1.00 protein_coding synonymous_variant LOW 105C>T Ala35Ala
M0079792 NIJPBKJM_00003 2300 6 Skin 1.00 protein_coding synonymous_variant LOW 102T>C Asp34Asp
M0079793 NIJPBKJM_00003 2339 4 Skin 0.67 protein_coding missense_variant MODERATE 63C>G Asp21Glu
M0079794 NIJPBKJM_00003 2347 5 Skin 0.83 protein_coding synonymous_variant LOW 55C>T Leu19Leu
M0079795 NIJPBKJM_00003 2396 5 Skin 0.83 protein_coding synonymous_variant LOW 6G>A Lys2Lys
M0079796 NIJPBKJM_00001 144 4 Skin 0.67 protein_coding synonymous_variant LOW 813T>C Asn271Asn
M0079797 NIJPBKJM_00001 156 4 Skin 0.67 protein_coding synonymous_variant LOW 801G>T Ala267Ala
M0079798 NIJPBKJM_00001 189 4 Skin 0.67 protein_coding synonymous_variant LOW 768T>A Ala256Ala
M0079799 NIJPBKJM_00001 201 4 Skin 0.67 protein_coding synonymous_variant LOW 756T>A Ile252Ile
M0079800 NIJPBKJM_00001 225 4 Skin 0.67 protein_coding synonymous_variant LOW 732T>G Ala244Ala
M0079801 NIJPBKJM_00001 918 4 Skin 0.67 protein_coding synonymous_variant LOW 39C>T Tyr13Tyr
M0079802 NIJPBKJM_00001 72 3 Skin 0.50 protein_coding synonymous_variant LOW 885G>A Leu295Leu
M0079803 NIJPBKJM_00001 333 3 Skin 0.50 protein_coding synonymous_variant LOW 624T>C Tyr208Tyr
M0079804 NIJPBKJM_00001 336 3 Skin 0.50 protein_coding synonymous_variant LOW 621A>T Ala207Ala
M0079805 NIJPBKJM_00002 1510 3 Skin 0.50 protein_coding synonymous_variant LOW 198T>C Ile66Ile
M0079806 NIJPBKJM_00003 2375 4 Skin 0.67 protein_coding synonymous_variant LOW 27A>T Val9Val
M0079807 NIJPBKJM_00001 2441 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -1485A>T None
M0079808 NIJPBKJM_00001 744 3 Skin 0.50 protein_coding synonymous_variant LOW 213A>G Ala71Ala
M0079809 NIJPBKJM_00001 765 3 Skin 0.50 protein_coding synonymous_variant LOW 192C>T Gly64Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term