Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3208
  Reference Plasmid   MET0370_bin.4__k81_5251
  Reference Plasmid Size   17155
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0079824 OONDHLKC_00011 14714 5 Skin 0.29 protein_coding missense_variant MODERATE 34A>G Ser12Gly
M0079825 OONDHLKC_00012 15011 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -459C>G None
M0079826 OONDHLKC_00012 15766 4 Skin 0.24 protein_coding synonymous_variant LOW 297C>T Val99Val
M0079827 OONDHLKC_00009 16136 4 Skin 0.24 protein_coding downstream_gene_variant MODIFIER *4468G>A None
M0079828 OONDHLKC_00009 16224 6 Skin 0.35 protein_coding downstream_gene_variant MODIFIER *4556C>T None
M0079829 OONDHLKC_00009 16266 5 Skin 0.29 protein_coding downstream_gene_variant MODIFIER *4598A>C None
M0079830 OONDHLKC_00013 16343 4 Skin 0.24 protein_coding missense_variant MODERATE 410G>A Arg137His
M0079831 OONDHLKC_00013 16409 3 Skin 0.18 protein_coding missense_variant MODERATE 344T>C Leu115Pro
M0079832 OONDHLKC_00012 15156 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -314A>G None
M0079833 OONDHLKC_00012 15160 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -310T>C None
M0079834 OONDHLKC_00006 7983 3 Skin 0.18 protein_coding synonymous_variant LOW 219T>C Gly73Gly
M0079835 OONDHLKC_00006 8036 3 Skin 0.18 protein_coding missense_variant MODERATE 272A>C Asp91Ala
M0079836 OONDHLKC_00006 8145 3 Skin 0.18 protein_coding synonymous_variant LOW 381C>T Ala127Ala
M0079837 OONDHLKC_00006 8188 3 Skin 0.18 protein_coding missense_variant MODERATE 424A>C Ile142Leu
M0079838 OONDHLKC_00006 8222 3 Skin 0.18 protein_coding missense_variant MODERATE 458A>G Gln153Arg
M0079839 OONDHLKC_00006 8247 3 Skin 0.18 protein_coding synonymous_variant LOW 483A>G Leu161Leu
M0079840 OONDHLKC_00006 8388 3 Skin 0.18 protein_coding synonymous_variant LOW 624T>C Ala208Ala
M0079841 OONDHLKC_00006 8613 4 Skin 0.24 protein_coding synonymous_variant LOW 849G>A Lys283Lys
M0079842 OONDHLKC_00007 9270 3 Skin 0.18 protein_coding missense_variant MODERATE 348G>C Glu116Asp
M0079843 OONDHLKC_00001 1915 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -163A>G None
M0079844 OONDHLKC_00001 1981 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -97T>C None
M0079845 OONDHLKC_00001 2175 3 Skin 0.18 protein_coding missense_variant MODERATE 98G>A Arg33Gln
M0079846 OONDHLKC_00002 2515 3 Skin 0.18 protein_coding synonymous_variant LOW 18G>A Glu6Glu
M0079847 OONDHLKC_00004 2799 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -520A>G None
M0079848 OONDHLKC_00004 2987 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -332A>G None
M0079849 OONDHLKC_00004 3025 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -294T>C None
M0079850 OONDHLKC_00004 3075 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -244T>G None
M0079851 OONDHLKC_00003 3211 5 Skin 0.29 protein_coding missense_variant MODERATE 77T>C Leu26Ser
M0079852 OONDHLKC_00003 3224 5 Skin 0.29 protein_coding missense_variant MODERATE 64C>G Pro22Ala
M0079853 OONDHLKC_00003 3256 5 Skin 0.29 protein_coding missense_variant MODERATE 32T>C Phe11Ser
M0079854 OONDHLKC_00003 3279 5 Skin 0.29 protein_coding synonymous_variant LOW 9T>C Ala3Ala
M0079855 OONDHLKC_00003 3295 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -8G>A None
M0079856 OONDHLKC_00003 3298 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -11T>C None
M0079857 OONDHLKC_00003 3316 5 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -29C>T None
M0079858 OONDHLKC_00001 659 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1419C>T None
M0079859 OONDHLKC_00001 721 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1357A>G None
M0079860 OONDHLKC_00001 935 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1143C>T None
M0079861 OONDHLKC_00001 1039 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -1039T>G None
M0079862 OONDHLKC_00001 1047 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -1031A>G None
M0079863 OONDHLKC_00001 1205 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -873G>A None
M0079864 OONDHLKC_00001 1271 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -807G>A None
M0079865 OONDHLKC_00001 1334 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -744G>A None
M0079866 OONDHLKC_00001 1759 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -319A>G None
M0079867 OONDHLKC_00001 1943 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -135G>A None
M0079868 OONDHLKC_00004 3519 4 Skin 0.24 protein_coding synonymous_variant LOW 201G>A Ala67Ala
M0079869 OONDHLKC_00006 8491 3 Skin 0.18 protein_coding missense_variant MODERATE 727C>T His243Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term