Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C27
  Reference Plasmid   MET0459_bin.7__k81_38640
  Reference Plasmid Size   5875
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0080380 DOHOHHNK_00003 148 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -2189G>A None
M0080381 DOHOHHNK_00003 181 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -2156T>C None
M0080382 DOHOHHNK_00001 783 3 Skin 0.75 protein_coding missense_variant MODERATE 292G>A Glu98Lys
M0080383 DOHOHHNK_00001 830 4 Skin 1.00 protein_coding missense_variant MODERATE 245T>G Leu82Arg
M0080384 DOHOHHNK_00001 959 3 Skin 0.75 protein_coding missense_variant MODERATE 116C>T Thr39Ile
M0080385 DOHOHHNK_00002 2095 4 Skin 1.00 protein_coding synonymous_variant LOW 90A>G Lys30Lys
M0080386 DOHOHHNK_00001 2213 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -1139A>G None
M0080387 DOHOHHNK_00003 3464 4 Skin 1.00 protein_coding synonymous_variant LOW 1128C>A Pro376Pro
M0080388 DOHOHHNK_00004 3640 3 Skin 0.75 protein_coding synonymous_variant LOW 721T>C Leu241Leu
M0080389 DOHOHHNK_00004 3990 4 Skin 1.00 protein_coding missense_variant MODERATE 371T>C Val124Ala
M0080390 DOHOHHNK_00004 4018 3 Skin 0.75 protein_coding missense_variant MODERATE 343G>A Glu115Lys
M0080391 DOHOHHNK_00004 4043 3 Skin 0.75 protein_coding synonymous_variant LOW 318A>G Ala106Ala
M0080392 DOHOHHNK_00005 4406 3 Skin 0.75 protein_coding missense_variant MODERATE 1432A>C Thr478Pro
M0080393 DOHOHHNK_00005 5425 3 Skin 0.75 protein_coding missense_variant MODERATE 413G>T Gly138Val
M0141356 DOHOHHNK_00003 148 3 Vaginal 0.33 protein_coding upstream_gene_variant MODIFIER -2189G>A None
M0141357 DOHOHHNK_00003 181 5 Vaginal 0.56 protein_coding upstream_gene_variant MODIFIER -2156T>C None
M0141358 DOHOHHNK_00001 783 3 Vaginal 0.33 protein_coding missense_variant MODERATE 292G>A Glu98Lys
M0141359 DOHOHHNK_00001 830 5 Vaginal 0.56 protein_coding missense_variant MODERATE 245T>G Leu82Arg
M0141360 DOHOHHNK_00001 959 3 Vaginal 0.33 protein_coding missense_variant MODERATE 116C>T Thr39Ile
M0141361 DOHOHHNK_00002 2095 5 Vaginal 0.56 protein_coding synonymous_variant LOW 90A>G Lys30Lys
M0141362 DOHOHHNK_00001 2213 3 Vaginal 0.33 protein_coding upstream_gene_variant MODIFIER -1139A>G None
M0141363 DOHOHHNK_00003 3464 3 Vaginal 0.33 protein_coding synonymous_variant LOW 1128C>A Pro376Pro
M0141364 DOHOHHNK_00004 3640 3 Vaginal 0.33 protein_coding synonymous_variant LOW 721T>C Leu241Leu
M0141365 DOHOHHNK_00004 3990 5 Vaginal 0.56 protein_coding missense_variant MODERATE 371T>C Val124Ala
M0141366 DOHOHHNK_00004 4018 3 Vaginal 0.33 protein_coding missense_variant MODERATE 343G>A Glu115Lys
M0141367 DOHOHHNK_00004 4043 3 Vaginal 0.33 protein_coding synonymous_variant LOW 318A>G Ala106Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term