Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3221
  Reference Plasmid   MET0475_bin.3__k81_12646
  Reference Plasmid Size   15932
  Reference Plasmid GC Content   0.74
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0080396 INGIFHFD_00001 1031 6 Skin 0.40 protein_coding missense_variant MODERATE 1175G>C Arg392Pro
M0080397 INGIFHFD_00001 1034 3 Skin 0.20 protein_coding missense_variant MODERATE 1172A>C Glu391Ala
M0080398 INGIFHFD_00003 3254 7 Skin 0.47 protein_coding synonymous_variant LOW 519G>C Pro173Pro
M0080399 INGIFHFD_00001 5073 4 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -2868A>C None
M0080400 INGIFHFD_00001 5949 3 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -3744C>T None
M0080401 INGIFHFD_00006 6061 3 Skin 0.20 protein_coding missense_variant MODERATE 1070A>G Gln357Arg
M0080402 INGIFHFD_00006 6110 3 Skin 0.20 protein_coding missense_variant MODERATE 1021A>C Met341Leu
M0080403 INGIFHFD_00006 6147 3 Skin 0.20 protein_coding synonymous_variant LOW 984T>C Gly328Gly
M0080404 INGIFHFD_00014 14508 3 Skin 0.20 protein_coding synonymous_variant LOW 111G>C Leu37Leu
M0080405 INGIFHFD_00015 15130 3 Skin 0.20 protein_coding missense_variant MODERATE 247G>A Ala83Thr
M0080406 INGIFHFD_00016 15767 3 Skin 0.20 protein_coding synonymous_variant LOW 39A>G Thr13Thr
M0080407 INGIFHFD_00001 135 7 Skin 0.47 protein_coding downstream_gene_variant MODIFIER *631T>C None
M0080408 INGIFHFD_00001 2071 3 Skin 0.20 protein_coding synonymous_variant LOW 135A>C Ala45Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term