Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C29
  Reference Plasmid   MET0639_bin.29__k81_107757
  Reference Plasmid Size   2710
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0081641 BILKOEIO_00001 265 3 Skin 1.00 protein_coding synonymous_variant LOW 132T>C Gly44Gly
M0081642 BILKOEIO_00002 479 3 Skin 1.00 protein_coding synonymous_variant LOW 837A>C Val279Val
M0081643 BILKOEIO_00002 503 3 Skin 1.00 protein_coding synonymous_variant LOW 813G>A Val271Val
M0081644 BILKOEIO_00002 629 3 Skin 1.00 protein_coding synonymous_variant LOW 687C>T Gly229Gly
M0081645 BILKOEIO_00002 641 3 Skin 1.00 protein_coding synonymous_variant LOW 675A>T Ala225Ala
M0081646 BILKOEIO_00002 912 3 Skin 1.00 protein_coding missense_variant MODERATE 404A>G Lys135Arg
M0081647 BILKOEIO_00002 986 3 Skin 1.00 protein_coding synonymous_variant LOW 330T>G Gly110Gly
M0081648 BILKOEIO_00002 1001 3 Skin 1.00 protein_coding synonymous_variant LOW 315T>A Ala105Ala
M0081649 BILKOEIO_00002 1145 3 Skin 1.00 protein_coding synonymous_variant LOW 171C>T Asn57Asn
M0081650 BILKOEIO_00002 1208 3 Skin 1.00 protein_coding synonymous_variant LOW 108C>T Asn36Asn
M0081651 BILKOEIO_00002 1252 3 Skin 1.00 protein_coding missense_variant MODERATE 64A>G Thr22Ala
M0133687 BILKOEIO_00001 124 4 Oral 0.67 protein_coding synonymous_variant LOW 273C>T Arg91Arg
M0133688 BILKOEIO_00001 130 5 Oral 0.83 protein_coding synonymous_variant LOW 267G>A Ala89Ala
M0133689 BILKOEIO_00001 133 5 Oral 0.83 protein_coding synonymous_variant LOW 264T>C His88His
M0133690 BILKOEIO_00001 136 5 Oral 0.83 protein_coding synonymous_variant LOW 261A>C Arg87Arg
M0133691 BILKOEIO_00001 217 5 Oral 0.83 protein_coding synonymous_variant LOW 180C>T Tyr60Tyr
M0133692 BILKOEIO_00001 225 3 Oral 0.50 protein_coding missense_variant MODERATE 172A>G Ser58Gly
M0133693 BILKOEIO_00001 265 5 Oral 0.83 protein_coding synonymous_variant LOW 132T>C Gly44Gly
M0133694 BILKOEIO_00002 413 3 Oral 0.50 protein_coding synonymous_variant LOW 903T>C Gly301Gly
M0133695 BILKOEIO_00002 503 4 Oral 0.67 protein_coding synonymous_variant LOW 813G>A Val271Val
M0133696 BILKOEIO_00002 629 5 Oral 0.83 protein_coding synonymous_variant LOW 687C>T Gly229Gly
M0133697 BILKOEIO_00002 641 5 Oral 0.83 protein_coding synonymous_variant LOW 675A>T Ala225Ala
M0133698 BILKOEIO_00002 710 6 Oral 1.00 protein_coding synonymous_variant LOW 606T>C Ile202Ile
M0133699 BILKOEIO_00002 912 4 Oral 0.67 protein_coding missense_variant MODERATE 404A>G Lys135Arg
M0133700 BILKOEIO_00002 913 4 Oral 0.67 protein_coding missense_variant MODERATE 403A>C Lys135Gln
M0133701 BILKOEIO_00002 914 4 Oral 0.67 protein_coding synonymous_variant LOW 402C>T Gly134Gly
M0133702 BILKOEIO_00002 1070 5 Oral 0.83 protein_coding synonymous_variant LOW 246C>T Leu82Leu
M0133703 BILKOEIO_00002 1124 5 Oral 0.83 protein_coding synonymous_variant LOW 192T>C Gly64Gly
M0133704 BILKOEIO_00002 1208 6 Oral 1.00 protein_coding synonymous_variant LOW 108C>T Asn36Asn
M0133705 BILKOEIO_00002 1274 6 Oral 1.00 protein_coding synonymous_variant LOW 42T>C Gly14Gly
M0133706 BILKOEIO_00002 479 4 Oral 0.67 protein_coding synonymous_variant LOW 837A>C Val279Val
M0133707 BILKOEIO_00002 956 3 Oral 0.50 protein_coding synonymous_variant LOW 360T>C Leu120Leu
M0133708 BILKOEIO_00002 1097 4 Oral 0.67 protein_coding synonymous_variant LOW 219C>T Pro73Pro
M0133709 BILKOEIO_00002 1100 4 Oral 0.67 protein_coding synonymous_variant LOW 216T>C Asp72Asp
M0133710 BILKOEIO_00002 1133 3 Oral 0.50 protein_coding synonymous_variant LOW 183C>T Tyr61Tyr
M0133711 BILKOEIO_00002 1145 4 Oral 0.67 protein_coding synonymous_variant LOW 171C>T Asn57Asn
M0133712 BILKOEIO_00001 1350 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -954C>T None
M0133713 BILKOEIO_00001 1380 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -984C>G None
M0133714 BILKOEIO_00001 1381 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -985A>G None
M0133715 BILKOEIO_00001 1382 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -986T>G None
M0133716 BILKOEIO_00001 1384 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -988T>C None
M0133717 BILKOEIO_00001 1385 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -989C>T None
M0133718 BILKOEIO_00001 1387 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -991C>A None
M0133719 BILKOEIO_00001 1391 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -995C>G None
M0133720 BILKOEIO_00001 298 3 Oral 0.50 protein_coding synonymous_variant LOW 99C>G Gly33Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term