Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3258
  Reference Plasmid   MET0662_bin.17__k81_27978
  Reference Plasmid Size   2640
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0082718 IKLHADOM_00001 151 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -25C>G None
M0082719 IKLHADOM_00001 205 4 Skin 1.00 protein_coding synonymous_variant LOW 30T>A Gly10Gly
M0082720 IKLHADOM_00001 220 3 Skin 0.75 protein_coding synonymous_variant LOW 45T>C Ser15Ser
M0082721 IKLHADOM_00001 238 3 Skin 0.75 protein_coding synonymous_variant LOW 63G>C Ala21Ala
M0082722 IKLHADOM_00001 253 3 Skin 0.75 protein_coding synonymous_variant LOW 78G>A Arg26Arg
M0082723 IKLHADOM_00001 257 4 Skin 1.00 protein_coding missense_variant MODERATE 82T>C Trp28Arg
M0082724 IKLHADOM_00001 295 4 Skin 1.00 protein_coding synonymous_variant LOW 120T>C Thr40Thr
M0082725 IKLHADOM_00001 307 4 Skin 1.00 protein_coding synonymous_variant LOW 132T>G Val44Val
M0082726 IKLHADOM_00001 310 4 Skin 1.00 protein_coding synonymous_variant LOW 135C>G Gly45Gly
M0082727 IKLHADOM_00001 313 4 Skin 1.00 protein_coding synonymous_variant LOW 138T>C Leu46Leu
M0082728 IKLHADOM_00001 796 4 Skin 1.00 protein_coding synonymous_variant LOW 621C>T Gly207Gly
M0082729 IKLHADOM_00001 808 3 Skin 0.75 protein_coding synonymous_variant LOW 633A>G Leu211Leu
M0082730 IKLHADOM_00002 874 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -57A>T None
M0082731 IKLHADOM_00002 875 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -56C>A None
M0082732 IKLHADOM_00002 1224 4 Skin 1.00 protein_coding synonymous_variant LOW 294A>G Gln98Gln
M0082733 IKLHADOM_00002 1335 3 Skin 0.75 protein_coding synonymous_variant LOW 405T>A Gly135Gly
M0082734 IKLHADOM_00002 1953 3 Skin 0.75 protein_coding synonymous_variant LOW 1023T>C Arg341Arg
M0082735 IKLHADOM_00002 2024 3 Skin 0.75 protein_coding missense_variant MODERATE 1094T>C Val365Ala
M0082736 IKLHADOM_00002 2037 4 Skin 1.00 protein_coding synonymous_variant LOW 1107T>C Val369Val
M0082737 IKLHADOM_00002 2091 3 Skin 0.75 protein_coding synonymous_variant LOW 1161A>T Ile387Ile
M0082738 IKLHADOM_00001 2358 3 Skin 0.75 protein_coding downstream_gene_variant MODIFIER *1547A>G None
M0082739 IKLHADOM_00001 412 3 Skin 0.75 protein_coding synonymous_variant LOW 237C>G Thr79Thr
M0082740 IKLHADOM_00002 1194 3 Skin 0.75 protein_coding synonymous_variant LOW 264C>T His88His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term