Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3266
  Reference Plasmid   MET0700_bin.25__k81_438
  Reference Plasmid Size   4855
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0082868 BABNNEFD_00002 1958 3 Skin 0.75 protein_coding missense_variant MODERATE 776T>C Val259Ala
M0082869 BABNNEFD_00002 2191 3 Skin 0.75 protein_coding synonymous_variant LOW 543T>G Ala181Ala
M0082870 BABNNEFD_00002 2236 3 Skin 0.75 protein_coding synonymous_variant LOW 498A>G Glu166Glu
M0082871 BABNNEFD_00001 2734 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -1213C>T None
M0082872 BABNNEFD_00003 2813 3 Skin 0.75 protein_coding missense_variant MODERATE 2017A>C Met673Leu
M0082873 BABNNEFD_00003 2844 3 Skin 0.75 protein_coding synonymous_variant LOW 1986A>C Thr662Thr
M0082874 BABNNEFD_00003 2871 3 Skin 0.75 protein_coding synonymous_variant LOW 1959A>G Ser653Ser
M0082875 BABNNEFD_00003 2982 3 Skin 0.75 protein_coding synonymous_variant LOW 1848G>C Ser616Ser
M0082876 BABNNEFD_00003 3372 3 Skin 0.75 protein_coding synonymous_variant LOW 1458T>C Asp486Asp
M0082877 BABNNEFD_00003 3441 3 Skin 0.75 protein_coding synonymous_variant LOW 1389T>C Val463Val
M0082878 BABNNEFD_00003 3729 3 Skin 0.75 protein_coding synonymous_variant LOW 1101T>C Arg367Arg
M0082879 BABNNEFD_00003 3732 3 Skin 0.75 protein_coding synonymous_variant LOW 1098C>T Asp366Asp
M0082880 BABNNEFD_00003 3747 3 Skin 0.75 protein_coding synonymous_variant LOW 1083G>C Val361Val
M0082881 BABNNEFD_00003 3754 3 Skin 0.75 protein_coding missense_variant MODERATE 1076C>G Ala359Gly
M0082882 BABNNEFD_00003 3786 3 Skin 0.75 protein_coding synonymous_variant LOW 1044T>C Asp348Asp
M0082883 BABNNEFD_00003 3798 3 Skin 0.75 protein_coding synonymous_variant LOW 1032T>A Ala344Ala
M0082884 BABNNEFD_00003 3945 3 Skin 0.75 protein_coding synonymous_variant LOW 885T>C Ser295Ser
M0082885 BABNNEFD_00003 3951 3 Skin 0.75 protein_coding synonymous_variant LOW 879T>C Arg293Arg
M0082886 BABNNEFD_00003 4257 3 Skin 0.75 protein_coding synonymous_variant LOW 573G>A Gln191Gln
M0082887 BABNNEFD_00003 4287 3 Skin 0.75 protein_coding synonymous_variant LOW 543G>A Leu181Leu
M0082888 BABNNEFD_00003 4377 3 Skin 0.75 protein_coding synonymous_variant LOW 453T>C Val151Val
M0082889 BABNNEFD_00003 4403 3 Skin 0.75 protein_coding missense_variant MODERATE 427T>G Phe143Val
M0082890 BABNNEFD_00003 4470 3 Skin 0.75 protein_coding synonymous_variant LOW 360G>C Thr120Thr
M0082891 BABNNEFD_00003 4527 3 Skin 0.75 protein_coding synonymous_variant LOW 303T>C Gly101Gly
M0082892 BABNNEFD_00003 4536 3 Skin 0.75 protein_coding synonymous_variant LOW 294C>T Asn98Asn
M0082893 BABNNEFD_00003 4598 3 Skin 0.75 protein_coding synonymous_variant LOW 232T>C Leu78Leu
M0082894 BABNNEFD_00003 4599 3 Skin 0.75 protein_coding synonymous_variant LOW 231T>C Ala77Ala
M0082895 BABNNEFD_00003 4620 3 Skin 0.75 protein_coding synonymous_variant LOW 210G>C Arg70Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term