Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C30
  Reference Plasmid   MET0772_bin.18__k81_361979
  Reference Plasmid Size   2140
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0083525 MMKMGIIH_00001 384 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -160T>C None
M0083526 MMKMGIIH_00001 386 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -158C>T None
M0083527 MMKMGIIH_00001 396 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -148G>A None
M0083528 MMKMGIIH_00001 411 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -133T>C None
M0083529 MMKMGIIH_00001 413 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -131G>T None
M0083530 MMKMGIIH_00001 423 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -121G>T None
M0083531 MMKMGIIH_00001 439 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -105C>T None
M0083532 MMKMGIIH_00001 441 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -103T>C None
M0083533 MMKMGIIH_00001 444 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -100T>C None
M0083534 MMKMGIIH_00001 453 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -91T>A None
M0083535 MMKMGIIH_00001 455 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -89T>G None
M0083536 MMKMGIIH_00001 502 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -42T>C None
M0083537 MMKMGIIH_00001 521 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -23T>C None
M0083538 MMKMGIIH_00001 523 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -21T>C None
M0083539 MMKMGIIH_00001 610 5 Skin 0.56 protein_coding missense_variant MODERATE 67A>G Thr23Ala
M0083540 MMKMGIIH_00001 657 5 Skin 0.56 protein_coding synonymous_variant LOW 114A>T Gly38Gly
M0083541 MMKMGIIH_00001 709 5 Skin 0.56 protein_coding missense_variant MODERATE 166G>C Glu56Gln
M0083542 MMKMGIIH_00001 738 6 Skin 0.67 protein_coding synonymous_variant LOW 195T>C His65His
M0083543 MMKMGIIH_00001 765 5 Skin 0.56 protein_coding synonymous_variant LOW 222C>T Ser74Ser
M0083544 MMKMGIIH_00001 780 6 Skin 0.67 protein_coding synonymous_variant LOW 237T>C Ala79Ala
M0083545 MMKMGIIH_00001 787 6 Skin 0.67 protein_coding missense_variant MODERATE 244A>G Ile82Val
M0083546 MMKMGIIH_00001 792 6 Skin 0.67 protein_coding synonymous_variant LOW 249G>A Glu83Glu
M0083547 MMKMGIIH_00001 804 6 Skin 0.67 protein_coding missense_variant MODERATE 261T>G Asp87Glu
M0083548 MMKMGIIH_00001 816 6 Skin 0.67 protein_coding synonymous_variant LOW 273G>C Ala91Ala
M0083549 MMKMGIIH_00001 819 6 Skin 0.67 protein_coding synonymous_variant LOW 276C>G Val92Val
M0083550 MMKMGIIH_00001 846 6 Skin 0.67 protein_coding synonymous_variant LOW 303C>T Ser101Ser
M0083551 MMKMGIIH_00001 849 6 Skin 0.67 protein_coding synonymous_variant LOW 306A>G Ala102Ala
M0083552 MMKMGIIH_00001 906 4 Skin 0.44 protein_coding synonymous_variant LOW 363G>T Pro121Pro
M0083553 MMKMGIIH_00001 926 4 Skin 0.44 protein_coding missense_variant MODERATE 383A>T Tyr128Phe
M0083554 MMKMGIIH_00001 978 5 Skin 0.56 protein_coding synonymous_variant LOW 435A>G Gln145Gln
M0083555 MMKMGIIH_00001 999 5 Skin 0.56 protein_coding synonymous_variant LOW 456T>C Ala152Ala
M0083556 MMKMGIIH_00001 1041 5 Skin 0.56 protein_coding synonymous_variant LOW 498T>C Arg166Arg
M0083557 MMKMGIIH_00001 1049 9 Skin 1.00 protein_coding missense_variant MODERATE 506T>C Ile169Thr
M0083558 MMKMGIIH_00001 1050 5 Skin 0.56 protein_coding missense_variant MODERATE 507C>G Ile169Met
M0083559 MMKMGIIH_00001 1056 5 Skin 0.56 protein_coding synonymous_variant LOW 513C>G Leu171Leu
M0083560 MMKMGIIH_00001 1062 5 Skin 0.56 protein_coding synonymous_variant LOW 519G>C Gly173Gly
M0083561 MMKMGIIH_00001 1068 5 Skin 0.56 protein_coding synonymous_variant LOW 525G>C Ala175Ala
M0083562 MMKMGIIH_00001 1084 5 Skin 0.56 protein_coding missense_variant MODERATE 541G>A Val181Ile
M0083563 MMKMGIIH_00001 1113 5 Skin 0.56 protein_coding synonymous_variant LOW 570C>G Arg190Arg
M0083564 MMKMGIIH_00001 1122 5 Skin 0.56 protein_coding synonymous_variant LOW 579G>T Val193Val
M0083565 MMKMGIIH_00001 1128 4 Skin 0.44 protein_coding synonymous_variant LOW 585G>A Gln195Gln
M0083566 MMKMGIIH_00001 1131 5 Skin 0.56 protein_coding synonymous_variant LOW 588C>T Gly196Gly
M0083567 MMKMGIIH_00001 1135 5 Skin 0.56 protein_coding missense_variant MODERATE 592T>A Phe198Ile
M0083568 MMKMGIIH_00001 1176 4 Skin 0.44 protein_coding synonymous_variant LOW 633C>T Asp211Asp
M0083569 MMKMGIIH_00001 1233 4 Skin 0.44 protein_coding synonymous_variant LOW 690C>T Arg230Arg
M0083570 MMKMGIIH_00001 1260 5 Skin 0.56 protein_coding synonymous_variant LOW 717C>G Leu239Leu
M0083571 MMKMGIIH_00001 1344 6 Skin 0.67 protein_coding synonymous_variant LOW 801C>T Ile267Ile
M0083572 MMKMGIIH_00001 1431 5 Skin 0.56 protein_coding synonymous_variant LOW 888A>G Arg296Arg
M0083573 MMKMGIIH_00001 1440 4 Skin 0.44 protein_coding synonymous_variant LOW 897G>A Glu299Glu
M0083574 MMKMGIIH_00001 1645 5 Skin 0.56 protein_coding synonymous_variant LOW 1102T>C Leu368Leu
M0083575 MMKMGIIH_00001 1665 5 Skin 0.56 protein_coding synonymous_variant LOW 1122C>G Arg374Arg
M0083576 MMKMGIIH_00001 1666 5 Skin 0.56 protein_coding synonymous_variant LOW 1123T>C Leu375Leu
M0083577 MMKMGIIH_00001 1728 6 Skin 0.67 protein_coding synonymous_variant LOW 1185T>C Ile395Ile
M0083578 MMKMGIIH_00001 1765 6 Skin 0.67 protein_coding missense_variant MODERATE 1222A>G Ile408Val
M0083579 MMKMGIIH_00001 1767 6 Skin 0.67 protein_coding synonymous_variant LOW 1224C>T Ile408Ile
M0083580 MMKMGIIH_00001 1779 6 Skin 0.67 protein_coding synonymous_variant LOW 1236A>G Ala412Ala
M0083581 MMKMGIIH_00001 1791 5 Skin 0.56 protein_coding synonymous_variant LOW 1248C>T Gly416Gly
M0083582 MMKMGIIH_00001 1809 6 Skin 0.67 protein_coding synonymous_variant LOW 1266T>C Tyr422Tyr
M0083583 MMKMGIIH_00001 1845 5 Skin 0.56 protein_coding synonymous_variant LOW 1302T>C Gly434Gly
M0083584 MMKMGIIH_00001 1859 8 Skin 0.89 protein_coding missense_variant MODERATE 1316G>C Gly439Ala
M0083585 MMKMGIIH_00001 1860 6 Skin 0.67 protein_coding synonymous_variant LOW 1317G>C Gly439Gly
M0083586 MMKMGIIH_00001 1869 6 Skin 0.67 protein_coding synonymous_variant LOW 1326C>T Asp442Asp
M0083587 MMKMGIIH_00001 1872 6 Skin 0.67 protein_coding synonymous_variant LOW 1329T>G Ala443Ala
M0083588 MMKMGIIH_00001 1899 6 Skin 0.67 protein_coding synonymous_variant LOW 1356C>T Gly452Gly
M0083589 MMKMGIIH_00001 2044 4 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *88T>C None
M0083590 MMKMGIIH_00001 1557 5 Skin 0.56 protein_coding synonymous_variant LOW 1014C>G Val338Val
M0083591 MMKMGIIH_00001 1503 4 Skin 0.44 protein_coding synonymous_variant LOW 960C>T Leu320Leu
M0083592 MMKMGIIH_00001 1533 4 Skin 0.44 protein_coding synonymous_variant LOW 990C>T Ala330Ala
M0083593 MMKMGIIH_00001 1536 4 Skin 0.44 protein_coding synonymous_variant LOW 993C>G Arg331Arg
M0083594 MMKMGIIH_00001 1569 4 Skin 0.44 protein_coding synonymous_variant LOW 1026C>T Leu342Leu
M0083595 MMKMGIIH_00001 1596 4 Skin 0.44 protein_coding synonymous_variant LOW 1053C>T Pro351Pro
M0133769 MMKMGIIH_00001 1049 6 Oral 1.00 protein_coding missense_variant MODERATE 506T>C Ile169Thr
M0133770 MMKMGIIH_00001 1503 6 Oral 1.00 protein_coding synonymous_variant LOW 960C>T Leu320Leu
M0133771 MMKMGIIH_00001 1533 6 Oral 1.00 protein_coding synonymous_variant LOW 990C>T Ala330Ala
M0133772 MMKMGIIH_00001 1536 6 Oral 1.00 protein_coding synonymous_variant LOW 993C>G Arg331Arg
M0133773 MMKMGIIH_00001 1557 6 Oral 1.00 protein_coding synonymous_variant LOW 1014C>G Val338Val
M0133774 MMKMGIIH_00001 1569 6 Oral 1.00 protein_coding synonymous_variant LOW 1026C>T Leu342Leu
M0133775 MMKMGIIH_00001 1596 6 Oral 1.00 protein_coding synonymous_variant LOW 1053C>T Pro351Pro
M0133776 MMKMGIIH_00001 1859 6 Oral 1.00 protein_coding missense_variant MODERATE 1316G>C Gly439Ala
M0133777 MMKMGIIH_00001 150 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -394T>C None
M0133778 MMKMGIIH_00001 195 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -349T>C None
M0133779 MMKMGIIH_00001 196 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -348A>G None
M0133780 MMKMGIIH_00001 228 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -316A>G None
M0133781 MMKMGIIH_00001 231 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -313A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term