Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3284
  Reference Plasmid   MET0776_bin.3__k81_26122
  Reference Plasmid Size   35076
  Reference Plasmid GC Content   0.59
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0083775 CPJIICAD_00016 10736 3 Skin 0.43 protein_coding missense_variant MODERATE 503G>A Arg168His
M0083776 CPJIICAD_00016 10752 3 Skin 0.43 protein_coding missense_variant MODERATE 487A>G Thr163Ala
M0083777 CPJIICAD_00016 10754 3 Skin 0.43 protein_coding missense_variant MODERATE 485A>C Asn162Thr
M0083778 CPJIICAD_00016 10763 3 Skin 0.43 protein_coding missense_variant MODERATE 476T>C Val159Ala
M0083779 CPJIICAD_00016 10765 3 Skin 0.43 protein_coding synonymous_variant LOW 474A>G Ser158Ser
M0083780 CPJIICAD_00016 10767 3 Skin 0.43 protein_coding missense_variant MODERATE 472T>G Ser158Ala
M0083781 CPJIICAD_00016 10768 3 Skin 0.43 protein_coding synonymous_variant LOW 471T>C Val157Val
M0083782 CPJIICAD_00016 10799 3 Skin 0.43 protein_coding missense_variant MODERATE 440A>G Lys147Arg
M0083783 CPJIICAD_00016 10827 4 Skin 0.57 protein_coding missense_variant MODERATE 412A>G Met138Val
M0083784 CPJIICAD_00016 10828 4 Skin 0.57 protein_coding synonymous_variant LOW 411C>T Ser137Ser
M0083785 CPJIICAD_00016 10834 3 Skin 0.43 protein_coding synonymous_variant LOW 405C>T Asn135Asn
M0083786 CPJIICAD_00016 10853 3 Skin 0.43 protein_coding missense_variant MODERATE 386C>T Ser129Leu
M0083787 CPJIICAD_00016 10862 3 Skin 0.43 protein_coding missense_variant MODERATE 377A>G Gln126Arg
M0083788 CPJIICAD_00016 10897 3 Skin 0.43 protein_coding synonymous_variant LOW 342T>C Tyr114Tyr
M0083789 CPJIICAD_00016 11022 3 Skin 0.43 protein_coding missense_variant MODERATE 217T>C Ser73Pro
M0083790 CPJIICAD_00016 11026 3 Skin 0.43 protein_coding synonymous_variant LOW 213A>G Pro71Pro
M0083791 CPJIICAD_00016 11050 3 Skin 0.43 protein_coding missense_variant MODERATE 189C>G His63Gln
M0083792 CPJIICAD_00016 11123 4 Skin 0.57 protein_coding missense_variant MODERATE 116C>G Thr39Ser
M0083793 CPJIICAD_00010 11323 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -4594A>G None
M0083794 CPJIICAD_00017 11347 3 Skin 0.43 protein_coding missense_variant MODERATE 1968C>A His656Gln
M0083795 CPJIICAD_00017 11404 3 Skin 0.43 protein_coding synonymous_variant LOW 1911C>T Pro637Pro
M0083796 CPJIICAD_00010 10369 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3640T>C None
M0083797 CPJIICAD_00010 10624 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3895G>A None
M0083798 CPJIICAD_00010 10663 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3934C>T None
M0083799 CPJIICAD_00010 10665 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3936A>G None
M0083800 CPJIICAD_00010 10666 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3937G>A None
M0083801 CPJIICAD_00010 10668 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3939C>G None
M0083802 CPJIICAD_00010 10669 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3940C>G None
M0083803 CPJIICAD_00016 11059 3 Skin 0.43 protein_coding synonymous_variant LOW 180C>A Arg60Arg
M0083804 CPJIICAD_00017 11464 3 Skin 0.43 protein_coding synonymous_variant LOW 1851T>C His617His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term