Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3290
  Reference Plasmid   MET1046_bin.2__k81_15669
  Reference Plasmid Size   6930
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0084491 OLLACGAA_00003 1900 6 Skin 1.00 protein_coding synonymous_variant LOW 291G>A Leu97Leu
M0084492 OLLACGAA_00003 1968 3 Skin 0.50 protein_coding missense_variant MODERATE 359G>C Gly120Ala
M0084493 OLLACGAA_00004 2563 3 Skin 0.50 protein_coding missense_variant MODERATE 284C>T Ala95Val
M0084494 OLLACGAA_00006 3677 6 Skin 1.00 protein_coding missense_variant MODERATE 646A>G Thr216Ala
M0084495 OLLACGAA_00006 3727 6 Skin 1.00 protein_coding synonymous_variant LOW 696T>C Thr232Thr
M0084496 OLLACGAA_00007 5247 3 Skin 0.50 protein_coding synonymous_variant LOW 840A>G Val280Val
M0084497 OLLACGAA_00005 2791 3 Skin 0.50 protein_coding synonymous_variant LOW 189G>A Gln63Gln
M0084498 OLLACGAA_00005 2792 4 Skin 0.67 protein_coding missense_variant MODERATE 190A>G Asn64Asp
M0084499 OLLACGAA_00005 2888 5 Skin 0.83 protein_coding missense_variant MODERATE 286A>G Ile96Val
M0084500 OLLACGAA_00005 2897 3 Skin 0.50 protein_coding missense_variant MODERATE 295G>A Asp99Asn
M0084501 OLLACGAA_00006 3194 3 Skin 0.50 protein_coding missense_variant MODERATE 163A>G Lys55Glu
M0084502 OLLACGAA_00006 3217 3 Skin 0.50 protein_coding missense_variant MODERATE 186A>C Glu62Asp
M0084503 OLLACGAA_00002 1185 3 Skin 0.50 protein_coding synonymous_variant LOW 210G>A Val70Val
M0084504 OLLACGAA_00003 2029 3 Skin 0.50 protein_coding synonymous_variant LOW 420G>A Ser140Ser
M0084505 OLLACGAA_00005 2605 3 Skin 0.50 protein_coding synonymous_variant LOW 3G>A Val1Val
M0084506 OLLACGAA_00005 2619 3 Skin 0.50 protein_coding missense_variant MODERATE 17T>C Ile6Thr
M0084507 OLLACGAA_00003 1920 3 Skin 0.50 protein_coding missense_variant MODERATE 311A>T Glu104Val
M0084508 OLLACGAA_00004 2261 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -19T>A None
M0084509 OLLACGAA_00004 2502 3 Skin 0.50 protein_coding missense_variant MODERATE 223A>C Asn75His
M0084510 OLLACGAA_00004 2506 3 Skin 0.50 protein_coding missense_variant MODERATE 227A>G His76Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term