Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3303
  Reference Plasmid   MGYG000298167__MGYG000298167_80
  Reference Plasmid Size   5735
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0134408 BBLBOPDI_00002 1968 3 Oral 0.50 protein_coding missense_variant MODERATE 941T>C Val314Ala
M0134409 BBLBOPDI_00002 1970 3 Oral 0.50 protein_coding synonymous_variant LOW 939C>T Thr313Thr
M0134410 BBLBOPDI_00002 2026 3 Oral 0.50 protein_coding missense_variant MODERATE 883A>C Ile295Leu
M0134411 BBLBOPDI_00002 2049 3 Oral 0.50 protein_coding missense_variant MODERATE 860G>A Arg287Lys
M0134412 BBLBOPDI_00003 3206 3 Oral 0.50 protein_coding missense_variant MODERATE 664A>G Ile222Val
M0134413 BBLBOPDI_00003 3336 4 Oral 0.67 protein_coding missense_variant MODERATE 534G>C Leu178Phe
M0134414 BBLBOPDI_00003 3338 4 Oral 0.67 protein_coding synonymous_variant LOW 532T>C Leu178Leu
M0134415 BBLBOPDI_00003 3360 4 Oral 0.67 protein_coding synonymous_variant LOW 510A>C Val170Val
M0134416 BBLBOPDI_00003 3384 3 Oral 0.50 protein_coding synonymous_variant LOW 486C>T Phe162Phe
M0134417 BBLBOPDI_00003 3387 3 Oral 0.50 protein_coding synonymous_variant LOW 483C>A Pro161Pro
M0134418 BBLBOPDI_00003 3498 3 Oral 0.50 protein_coding synonymous_variant LOW 372C>T Arg124Arg
M0134419 BBLBOPDI_00003 3516 3 Oral 0.50 protein_coding synonymous_variant LOW 354C>T Ala118Ala
M0134420 BBLBOPDI_00003 3552 3 Oral 0.50 protein_coding synonymous_variant LOW 318T>C His106His
M0134421 BBLBOPDI_00003 3558 4 Oral 0.67 protein_coding synonymous_variant LOW 312A>T Gly104Gly
M0134422 BBLBOPDI_00003 3570 4 Oral 0.67 protein_coding synonymous_variant LOW 300A>C Arg100Arg
M0134423 BBLBOPDI_00003 3597 3 Oral 0.50 protein_coding synonymous_variant LOW 273A>G Thr91Thr
M0134424 BBLBOPDI_00003 3609 3 Oral 0.50 protein_coding synonymous_variant LOW 261A>G Gln87Gln
M0134425 BBLBOPDI_00003 3627 3 Oral 0.50 protein_coding synonymous_variant LOW 243T>C Leu81Leu
M0134426 BBLBOPDI_00003 3633 3 Oral 0.50 protein_coding synonymous_variant LOW 237T>A Pro79Pro
M0134427 BBLBOPDI_00003 3636 3 Oral 0.50 protein_coding synonymous_variant LOW 234C>G Leu78Leu
M0134428 BBLBOPDI_00003 3666 3 Oral 0.50 protein_coding synonymous_variant LOW 204C>T Asn68Asn
M0134429 BBLBOPDI_00003 3720 3 Oral 0.50 protein_coding synonymous_variant LOW 150G>A Gly50Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term