Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3305
  Reference Plasmid   MGYG000298216__MGYG000298216_66
  Reference Plasmid Size   3614
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0134480 EKLMAPKI_00001 440 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -46T>G None
M0134481 EKLMAPKI_00001 454 5 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -60A>T None
M0134482 EKLMAPKI_00001 555 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -161G>A None
M0134483 EKLMAPKI_00001 579 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -185T>C None
M0134484 EKLMAPKI_00001 613 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -219C>T None
M0134485 EKLMAPKI_00001 642 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -248G>T None
M0134486 EKLMAPKI_00001 649 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -255A>G None
M0134487 EKLMAPKI_00001 650 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -256A>T None
M0134488 EKLMAPKI_00001 653 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -259G>A None
M0134489 EKLMAPKI_00001 655 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -261C>T None
M0134490 EKLMAPKI_00001 656 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -262A>C None
M0134491 EKLMAPKI_00001 744 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -350A>T None
M0134492 EKLMAPKI_00001 745 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -351A>T None
M0134493 EKLMAPKI_00001 746 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -352A>G None
M0134494 EKLMAPKI_00001 757 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -363A>C None
M0134495 EKLMAPKI_00001 758 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -364T>C None
M0134496 EKLMAPKI_00001 781 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -387T>C None
M0134497 EKLMAPKI_00001 804 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -410A>T None
M0134498 EKLMAPKI_00001 840 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -446T>A None
M0134499 EKLMAPKI_00001 861 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -467T>G None
M0134500 EKLMAPKI_00001 984 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -590A>G None
M0134501 EKLMAPKI_00001 996 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -602G>A None
M0134502 EKLMAPKI_00001 1014 5 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -620A>G None
M0134503 EKLMAPKI_00002 1545 3 Oral 0.60 protein_coding missense_variant MODERATE 76C>A Pro26Thr
M0134504 EKLMAPKI_00001 1794 5 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1400G>A None
M0134505 EKLMAPKI_00001 1872 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1478G>A None
M0134506 EKLMAPKI_00001 2070 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1676T>C None
M0134507 EKLMAPKI_00001 2200 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -1806G>A None
M0134508 EKLMAPKI_00001 2202 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -1808G>C None
M0134509 EKLMAPKI_00001 2208 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1814C>T None
M0134510 EKLMAPKI_00001 2211 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1817T>G None
M0134511 EKLMAPKI_00001 2281 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -1887T>C None
M0134512 EKLMAPKI_00001 2328 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1934T>C None
M0134513 EKLMAPKI_00003 2529 4 Oral 0.80 protein_coding missense_variant MODERATE 181G>C Ala61Pro
M0134514 EKLMAPKI_00003 2628 4 Oral 0.80 protein_coding missense_variant MODERATE 82A>G Asn28Asp
M0134515 EKLMAPKI_00001 2787 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -2393G>C None
M0134516 EKLMAPKI_00001 2859 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -2465C>G None
M0134517 EKLMAPKI_00004 3148 4 Oral 0.80 protein_coding synonymous_variant LOW 15T>C Asp5Asp
M0134518 EKLMAPKI_00001 595 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -201A>G None
M0134519 EKLMAPKI_00001 597 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -203T>C None
M0134520 EKLMAPKI_00001 1680 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -1286A>T None
M0134521 EKLMAPKI_00003 2643 3 Oral 0.60 protein_coding missense_variant MODERATE 67G>A Val23Ile
M0134522 EKLMAPKI_00004 3039 3 Oral 0.60 protein_coding missense_variant MODERATE 124T>A Ser42Thr
M0134523 EKLMAPKI_00001 3198 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -2804A>T None
M0134524 EKLMAPKI_00001 3222 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -2828A>C None
M0134525 EKLMAPKI_00001 3420 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -3026A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term