Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3306
  Reference Plasmid   MGYG000298223__MGYG000298223_68
  Reference Plasmid Size   7877
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0134526 DIEDGDLK_00002 1912 3 Oral 0.75 protein_coding synonymous_variant LOW 57T>C Thr19Thr
M0134527 DIEDGDLK_00003 2348 3 Oral 0.75 protein_coding synonymous_variant LOW 297T>C Val99Val
M0134528 DIEDGDLK_00002 2713 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -745T>C None
M0134529 DIEDGDLK_00004 2917 3 Oral 0.75 protein_coding missense_variant MODERATE 1246A>G Ile416Val
M0134530 DIEDGDLK_00004 3017 3 Oral 0.75 protein_coding synonymous_variant LOW 1146T>C Ile382Ile
M0134531 DIEDGDLK_00004 3610 4 Oral 1.00 protein_coding missense_variant MODERATE 553T>C Tyr185His
M0134532 DIEDGDLK_00004 3788 3 Oral 0.75 protein_coding synonymous_variant LOW 375T>C Tyr125Tyr
M0134533 DIEDGDLK_00004 4077 4 Oral 1.00 protein_coding missense_variant MODERATE 86T>C Leu29Pro
M0134534 DIEDGDLK_00006 5526 3 Oral 0.75 protein_coding synonymous_variant LOW 1341G>T Gly447Gly
M0134535 DIEDGDLK_00006 5790 3 Oral 0.75 protein_coding synonymous_variant LOW 1077A>C Ile359Ile
M0134536 DIEDGDLK_00006 6468 3 Oral 0.75 protein_coding synonymous_variant LOW 399T>C His133His
M0134537 DIEDGDLK_00004 7823 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -3661T>A None
M0134538 DIEDGDLK_00005 4209 3 Oral 0.75 protein_coding synonymous_variant LOW 858G>T Gly286Gly
M0134539 DIEDGDLK_00005 4596 3 Oral 0.75 protein_coding synonymous_variant LOW 471C>T Asp157Asp
M0134540 DIEDGDLK_00005 4599 3 Oral 0.75 protein_coding synonymous_variant LOW 468G>A Leu156Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term