Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3309
  Reference Plasmid   MGYG000298290__MGYG000298290_122
  Reference Plasmid Size   19173
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0134636 HKJPCNFK_00012 14388 3 Oral 0.33 protein_coding missense_variant MODERATE 23A>G His8Arg
M0134637 HKJPCNFK_00012 14404 3 Oral 0.33 protein_coding synonymous_variant LOW 39T>C Cys13Cys
M0134638 HKJPCNFK_00012 14405 3 Oral 0.33 protein_coding missense_variant MODERATE 40A>T Thr14Ser
M0134639 HKJPCNFK_00012 14428 3 Oral 0.33 protein_coding synonymous_variant LOW 63G>A Leu21Leu
M0134640 HKJPCNFK_00012 14590 4 Oral 0.44 protein_coding synonymous_variant LOW 225A>G Gln75Gln
M0134641 HKJPCNFK_00012 14597 4 Oral 0.44 protein_coding missense_variant MODERATE 232A>G Met78Val
M0134642 HKJPCNFK_00012 14734 4 Oral 0.44 protein_coding synonymous_variant LOW 369A>G Leu123Leu
M0134643 HKJPCNFK_00012 14740 4 Oral 0.44 protein_coding synonymous_variant LOW 375A>G Glu125Glu
M0134644 HKJPCNFK_00012 14770 4 Oral 0.44 protein_coding synonymous_variant LOW 405T>C Val135Val
M0134645 HKJPCNFK_00012 14779 3 Oral 0.33 protein_coding synonymous_variant LOW 414T>C Tyr138Tyr
M0134646 HKJPCNFK_00012 14785 4 Oral 0.44 protein_coding synonymous_variant LOW 420A>G Val140Val
M0134647 HKJPCNFK_00012 14800 4 Oral 0.44 protein_coding synonymous_variant LOW 435T>C Asn145Asn
M0134648 HKJPCNFK_00012 14806 4 Oral 0.44 protein_coding synonymous_variant LOW 441A>G Thr147Thr
M0134649 HKJPCNFK_00012 14809 4 Oral 0.44 protein_coding synonymous_variant LOW 444C>G Gly148Gly
M0134650 HKJPCNFK_00012 14818 4 Oral 0.44 protein_coding synonymous_variant LOW 453T>C Ala151Ala
M0134651 HKJPCNFK_00012 14821 4 Oral 0.44 protein_coding synonymous_variant LOW 456C>T Ser152Ser
M0134652 HKJPCNFK_00012 14824 4 Oral 0.44 protein_coding synonymous_variant LOW 459T>C Ile153Ile
M0134653 HKJPCNFK_00012 14845 3 Oral 0.33 protein_coding synonymous_variant LOW 480T>C Asn160Asn
M0134654 HKJPCNFK_00012 14890 3 Oral 0.33 protein_coding synonymous_variant LOW 525C>G Pro175Pro
M0134655 HKJPCNFK_00012 14911 3 Oral 0.33 protein_coding synonymous_variant LOW 546G>T Arg182Arg
M0134656 HKJPCNFK_00012 14914 3 Oral 0.33 protein_coding synonymous_variant LOW 549T>G Ser183Ser
M0134657 HKJPCNFK_00012 14974 3 Oral 0.33 protein_coding synonymous_variant LOW 609A>G Ala203Ala
M0134658 HKJPCNFK_00012 15007 3 Oral 0.33 protein_coding synonymous_variant LOW 642T>C Pro214Pro
M0134659 HKJPCNFK_00012 15067 3 Oral 0.33 protein_coding synonymous_variant LOW 702A>G Ala234Ala
M0134660 HKJPCNFK_00012 15091 3 Oral 0.33 protein_coding synonymous_variant LOW 726T>G Val242Val
M0134661 HKJPCNFK_00012 15112 3 Oral 0.33 protein_coding synonymous_variant LOW 747C>T Ile249Ile
M0134662 HKJPCNFK_00012 15128 3 Oral 0.33 protein_coding synonymous_variant LOW 763A>C Arg255Arg
M0134663 HKJPCNFK_00012 15553 4 Oral 0.44 protein_coding synonymous_variant LOW 1188A>G Ala396Ala
M0134664 HKJPCNFK_00012 15751 3 Oral 0.33 protein_coding synonymous_variant LOW 1386A>G Thr462Thr
M0134665 HKJPCNFK_00012 15760 3 Oral 0.33 protein_coding synonymous_variant LOW 1395A>T Ala465Ala
M0134666 HKJPCNFK_00012 15802 3 Oral 0.33 protein_coding synonymous_variant LOW 1437C>T Tyr479Tyr
M0134667 HKJPCNFK_00012 15906 4 Oral 0.44 protein_coding missense_variant MODERATE 1541G>A Ser514Asn
M0134668 HKJPCNFK_00012 15931 3 Oral 0.33 protein_coding synonymous_variant LOW 1566A>G Thr522Thr
M0134669 HKJPCNFK_00012 15938 3 Oral 0.33 protein_coding missense_variant MODERATE 1573T>C Phe525Leu
M0134670 HKJPCNFK_00012 15943 3 Oral 0.33 protein_coding synonymous_variant LOW 1578A>G Leu526Leu
M0134671 HKJPCNFK_00012 15961 4 Oral 0.44 protein_coding synonymous_variant LOW 1596A>G Thr532Thr
M0134672 HKJPCNFK_00012 15971 4 Oral 0.44 protein_coding synonymous_variant LOW 1606C>T Leu536Leu
M0134673 HKJPCNFK_00012 15980 4 Oral 0.44 protein_coding synonymous_variant LOW 1615T>C Leu539Leu
M0134674 HKJPCNFK_00012 15986 4 Oral 0.44 protein_coding missense_variant MODERATE 1621A>G Thr541Ala
M0134675 HKJPCNFK_00012 15988 4 Oral 0.44 protein_coding synonymous_variant LOW 1623G>T Thr541Thr
M0134676 HKJPCNFK_00012 16018 3 Oral 0.33 protein_coding synonymous_variant LOW 1653T>C Pro551Pro
M0134677 HKJPCNFK_00012 16081 4 Oral 0.44 protein_coding synonymous_variant LOW 1716T>C Asn572Asn
M0134678 HKJPCNFK_00012 16150 3 Oral 0.33 protein_coding synonymous_variant LOW 1785T>C Gly595Gly
M0134679 HKJPCNFK_00012 16243 3 Oral 0.33 protein_coding synonymous_variant LOW 1878T>C Gly626Gly
M0134680 HKJPCNFK_00012 16609 5 Oral 0.56 protein_coding synonymous_variant LOW 2244T>C Gly748Gly
M0134681 HKJPCNFK_00012 16651 3 Oral 0.33 protein_coding synonymous_variant LOW 2286T>G Thr762Thr
M0134682 HKJPCNFK_00012 16717 4 Oral 0.44 protein_coding synonymous_variant LOW 2352T>G Leu784Leu
M0134683 HKJPCNFK_00012 16819 4 Oral 0.44 protein_coding synonymous_variant LOW 2454T>C Gly818Gly
M0134684 HKJPCNFK_00012 16990 3 Oral 0.33 protein_coding synonymous_variant LOW 2625T>C Ser875Ser
M0134685 HKJPCNFK_00012 17002 4 Oral 0.44 protein_coding synonymous_variant LOW 2637T>A Gly879Gly
M0134686 HKJPCNFK_00012 17059 4 Oral 0.44 protein_coding synonymous_variant LOW 2694A>T Ala898Ala
M0134687 HKJPCNFK_00012 17065 4 Oral 0.44 protein_coding synonymous_variant LOW 2700C>T Asn900Asn
M0134688 HKJPCNFK_00012 17092 3 Oral 0.33 protein_coding synonymous_variant LOW 2727T>A Ala909Ala
M0134689 HKJPCNFK_00012 17305 5 Oral 0.56 protein_coding synonymous_variant LOW 2940T>C Gly980Gly
M0134690 HKJPCNFK_00012 17395 3 Oral 0.33 protein_coding synonymous_variant LOW 3030C>T Asn1010Asn
M0134691 HKJPCNFK_00013 17495 5 Oral 0.56 protein_coding synonymous_variant LOW 28C>T Leu10Leu
M0134692 HKJPCNFK_00013 17506 5 Oral 0.56 protein_coding synonymous_variant LOW 39T>G Ala13Ala
M0134693 HKJPCNFK_00013 17790 5 Oral 0.56 protein_coding missense_variant MODERATE 323T>C Val108Ala
M0134694 HKJPCNFK_00013 17809 4 Oral 0.44 protein_coding synonymous_variant LOW 342G>A Lys114Lys
M0134695 HKJPCNFK_00013 17821 5 Oral 0.56 protein_coding synonymous_variant LOW 354T>G Thr118Thr
M0134696 HKJPCNFK_00013 17866 4 Oral 0.44 protein_coding synonymous_variant LOW 399T>C Ala133Ala
M0134697 HKJPCNFK_00013 17957 5 Oral 0.56 protein_coding missense_variant MODERATE 490C>G Gln164Glu
M0134698 HKJPCNFK_00013 18010 5 Oral 0.56 protein_coding synonymous_variant LOW 543T>C Asp181Asp
M0134699 HKJPCNFK_00013 18037 3 Oral 0.33 protein_coding synonymous_variant LOW 570C>G Pro190Pro
M0134700 HKJPCNFK_00013 18229 5 Oral 0.56 protein_coding synonymous_variant LOW 762G>A Glu254Glu
M0134701 HKJPCNFK_00013 18253 4 Oral 0.44 protein_coding synonymous_variant LOW 786C>T Thr262Thr
M0134702 HKJPCNFK_00013 18265 3 Oral 0.33 protein_coding synonymous_variant LOW 798C>T Arg266Arg
M0134703 HKJPCNFK_00013 18394 5 Oral 0.56 protein_coding synonymous_variant LOW 927T>C Ile309Ile
M0134704 HKJPCNFK_00013 18511 5 Oral 0.56 protein_coding synonymous_variant LOW 1044A>C Pro348Pro
M0134705 HKJPCNFK_00013 18516 5 Oral 0.56 protein_coding missense_variant MODERATE 1049C>A Pro350His
M0134706 HKJPCNFK_00013 18517 5 Oral 0.56 protein_coding synonymous_variant LOW 1050C>G Pro350Pro
M0134707 HKJPCNFK_00013 18679 5 Oral 0.56 protein_coding synonymous_variant LOW 1212C>A Ala404Ala
M0134708 HKJPCNFK_00013 18710 4 Oral 0.44 protein_coding missense_variant MODERATE 1243T>G Ser415Ala
M0134709 HKJPCNFK_00013 18769 3 Oral 0.33 protein_coding synonymous_variant LOW 1302G>A Gln434Gln
M0134710 HKJPCNFK_00013 18823 5 Oral 0.56 protein_coding synonymous_variant LOW 1356A>G Glu452Glu
M0134711 HKJPCNFK_00013 18874 3 Oral 0.33 protein_coding synonymous_variant LOW 1407T>C Arg469Arg
M0134712 HKJPCNFK_00013 18898 5 Oral 0.56 protein_coding synonymous_variant LOW 1431A>C Gly477Gly
M0134713 HKJPCNFK_00013 18925 3 Oral 0.33 protein_coding synonymous_variant LOW 1458T>C Pro486Pro
M0134714 HKJPCNFK_00013 18977 3 Oral 0.33 protein_coding missense_variant MODERATE 1510C>A Gln504Lys
M0134715 HKJPCNFK_00013 19057 5 Oral 0.56 protein_coding synonymous_variant LOW 1590C>T His530His
M0134716 HKJPCNFK_00013 19064 5 Oral 0.56 protein_coding missense_variant MODERATE 1597C>G Pro533Ala
M0134717 HKJPCNFK_00006 6532 3 Oral 0.33 protein_coding synonymous_variant LOW 270T>C Pro90Pro
M0134718 HKJPCNFK_00006 6862 3 Oral 0.33 protein_coding synonymous_variant LOW 600A>G Lys200Lys
M0134719 HKJPCNFK_00006 6865 3 Oral 0.33 protein_coding synonymous_variant LOW 603G>A Leu201Leu
M0134720 HKJPCNFK_00006 6935 3 Oral 0.33 protein_coding missense_variant MODERATE 673G>T Ala225Ser
M0134721 HKJPCNFK_00006 6940 3 Oral 0.33 protein_coding synonymous_variant LOW 678T>C Phe226Phe
M0134722 HKJPCNFK_00006 7264 3 Oral 0.33 protein_coding synonymous_variant LOW 1002G>C Gly334Gly
M0134723 HKJPCNFK_00006 7297 3 Oral 0.33 protein_coding synonymous_variant LOW 1035A>T Ala345Ala
M0134724 HKJPCNFK_00008 9124 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -95G>A None
M0134725 HKJPCNFK_00008 9341 3 Oral 0.33 protein_coding synonymous_variant LOW 123C>A Thr41Thr
M0134726 HKJPCNFK_00008 9854 3 Oral 0.33 protein_coding synonymous_variant LOW 636A>G Lys212Lys
M0134727 HKJPCNFK_00008 9941 3 Oral 0.33 protein_coding synonymous_variant LOW 723G>A Arg241Arg
M0134728 HKJPCNFK_00008 10436 3 Oral 0.33 protein_coding synonymous_variant LOW 1218G>A Thr406Thr
M0134729 HKJPCNFK_00009 11966 3 Oral 0.33 protein_coding synonymous_variant LOW 1050A>G Gly350Gly
M0134730 HKJPCNFK_00010 12858 3 Oral 0.33 protein_coding synonymous_variant LOW 753G>A Gln251Gln
M0134731 HKJPCNFK_00010 13204 3 Oral 0.33 protein_coding synonymous_variant LOW 1099T>C Leu367Leu
M0134732 HKJPCNFK_00010 13248 3 Oral 0.33 protein_coding synonymous_variant LOW 1143C>T Ser381Ser
M0134733 HKJPCNFK_00010 13275 3 Oral 0.33 protein_coding synonymous_variant LOW 1170T>A Ser390Ser
M0134734 HKJPCNFK_00010 13287 3 Oral 0.33 protein_coding synonymous_variant LOW 1182G>A Gly394Gly
M0134735 HKJPCNFK_00010 13293 3 Oral 0.33 protein_coding missense_variant MODERATE 1188A>T Glu396Asp
M0134736 HKJPCNFK_00010 13386 3 Oral 0.33 protein_coding synonymous_variant LOW 1281A>G Val427Val
M0134737 HKJPCNFK_00010 13401 3 Oral 0.33 protein_coding synonymous_variant LOW 1296G>A Glu432Glu
M0134738 HKJPCNFK_00010 13407 3 Oral 0.33 protein_coding synonymous_variant LOW 1302G>A Leu434Leu
M0134739 HKJPCNFK_00010 13430 3 Oral 0.33 protein_coding missense_variant MODERATE 1325A>T Tyr442Phe
M0134740 HKJPCNFK_00010 13433 3 Oral 0.33 protein_coding missense_variant MODERATE 1328T>A Phe443Tyr
M0134741 HKJPCNFK_00010 13443 3 Oral 0.33 protein_coding synonymous_variant LOW 1338G>A Ala446Ala
M0134742 HKJPCNFK_00010 13477 3 Oral 0.33 protein_coding missense_variant MODERATE 1372G>A Val458Ile
M0134743 HKJPCNFK_00010 13485 3 Oral 0.33 protein_coding synonymous_variant LOW 1380C>T His460His
M0134744 HKJPCNFK_00010 13488 3 Oral 0.33 protein_coding synonymous_variant LOW 1383C>T Ile461Ile
M0134745 HKJPCNFK_00010 13491 3 Oral 0.33 protein_coding synonymous_variant LOW 1386T>C Asn462Asn
M0134746 HKJPCNFK_00010 13569 3 Oral 0.33 protein_coding synonymous_variant LOW 1464C>T Phe488Phe
M0134747 HKJPCNFK_00010 13596 3 Oral 0.33 protein_coding synonymous_variant LOW 1491A>G Gly497Gly
M0134748 HKJPCNFK_00010 13600 3 Oral 0.33 protein_coding synonymous_variant LOW 1495C>T Leu499Leu
M0134749 HKJPCNFK_00010 13614 3 Oral 0.33 protein_coding synonymous_variant LOW 1509C>T Ala503Ala
M0134750 HKJPCNFK_00010 13635 3 Oral 0.33 protein_coding synonymous_variant LOW 1530G>T Ser510Ser
M0134751 HKJPCNFK_00010 13662 3 Oral 0.33 protein_coding synonymous_variant LOW 1557C>T Asn519Asn
M0134752 HKJPCNFK_00010 13677 3 Oral 0.33 protein_coding synonymous_variant LOW 1572C>T Leu524Leu
M0134753 HKJPCNFK_00010 13797 3 Oral 0.33 protein_coding synonymous_variant LOW 1692C>T Cys564Cys
M0134754 HKJPCNFK_00010 13875 3 Oral 0.33 protein_coding synonymous_variant LOW 1770C>G Leu590Leu
M0134755 HKJPCNFK_00010 13881 3 Oral 0.33 protein_coding synonymous_variant LOW 1776C>T Ser592Ser
M0134756 HKJPCNFK_00010 13890 3 Oral 0.33 protein_coding synonymous_variant LOW 1785T>C Ile595Ile
M0134757 HKJPCNFK_00010 13900 3 Oral 0.33 protein_coding synonymous_variant LOW 1795T>C Leu599Leu
M0134758 HKJPCNFK_00010 13941 3 Oral 0.33 protein_coding synonymous_variant LOW 1836C>T Asp612Asp
M0134759 HKJPCNFK_00010 13986 3 Oral 0.33 protein_coding synonymous_variant LOW 1881A>G Leu627Leu
M0134760 HKJPCNFK_00010 13994 3 Oral 0.33 protein_coding missense_variant MODERATE 1889C>T Ala630Val
M0134761 HKJPCNFK_00010 13998 3 Oral 0.33 protein_coding synonymous_variant LOW 1893G>A Lys631Lys
M0134762 HKJPCNFK_00010 14040 3 Oral 0.33 protein_coding synonymous_variant LOW 1935A>G Thr645Thr
M0134763 HKJPCNFK_00011 14193 3 Oral 0.33 protein_coding missense_variant MODERATE 106A>T Thr36Ser
M0134764 HKJPCNFK_00012 16708 3 Oral 0.33 protein_coding synonymous_variant LOW 2343C>T Ala781Ala
M0134765 HKJPCNFK_00012 16777 3 Oral 0.33 protein_coding synonymous_variant LOW 2412C>T Pro804Pro
M0134766 HKJPCNFK_00012 17207 3 Oral 0.33 protein_coding missense_variant MODERATE 2842T>G Ser948Ala
M0134767 HKJPCNFK_00012 17209 3 Oral 0.33 protein_coding synonymous_variant LOW 2844T>C Ser948Ser
M0134768 HKJPCNFK_00012 17341 3 Oral 0.33 protein_coding synonymous_variant LOW 2976T>C Asn992Asn
M0134769 HKJPCNFK_00011 17456 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -3158G>A None
M0134770 HKJPCNFK_00013 18048 3 Oral 0.33 protein_coding missense_variant MODERATE 581C>G Thr194Ser
M0134771 HKJPCNFK_00013 18052 3 Oral 0.33 protein_coding synonymous_variant LOW 585C>T Gly195Gly
M0134772 HKJPCNFK_00013 18343 3 Oral 0.33 protein_coding synonymous_variant LOW 876C>T Asn292Asn
M0134773 HKJPCNFK_00013 18535 3 Oral 0.33 protein_coding synonymous_variant LOW 1068C>A Gly356Gly
M0134774 HKJPCNFK_00013 18565 3 Oral 0.33 protein_coding synonymous_variant LOW 1098C>G Thr366Thr
M0134775 HKJPCNFK_00013 18694 3 Oral 0.33 protein_coding synonymous_variant LOW 1227G>A Glu409Glu
M0134776 HKJPCNFK_00013 17932 3 Oral 0.33 protein_coding missense_variant MODERATE 465C>A Asp155Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term