Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3314
  Reference Plasmid   MGYG000298318__MGYG000298318_104
  Reference Plasmid Size   14645
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0135183 LAELIILP_00001 5490 5 Oral 0.71 protein_coding upstream_gene_variant MODIFIER -4698T>C None
M0135184 LAELIILP_00007 5753 4 Oral 0.57 protein_coding synonymous_variant LOW 3729C>G Val1243Val
M0135185 LAELIILP_00007 6023 4 Oral 0.57 protein_coding synonymous_variant LOW 3459C>T Asp1153Asp
M0135186 LAELIILP_00007 6035 4 Oral 0.57 protein_coding synonymous_variant LOW 3447T>C Ser1149Ser
M0135187 LAELIILP_00007 6104 5 Oral 0.71 protein_coding synonymous_variant LOW 3378T>C Leu1126Leu
M0135188 LAELIILP_00007 6122 5 Oral 0.71 protein_coding synonymous_variant LOW 3360T>C Asp1120Asp
M0135189 LAELIILP_00007 6128 5 Oral 0.71 protein_coding synonymous_variant LOW 3354T>C Ile1118Ile
M0135190 LAELIILP_00007 6131 5 Oral 0.71 protein_coding synonymous_variant LOW 3351T>C Tyr1117Tyr
M0135191 LAELIILP_00007 6140 5 Oral 0.71 protein_coding synonymous_variant LOW 3342T>C Arg1114Arg
M0135192 LAELIILP_00007 6155 4 Oral 0.57 protein_coding synonymous_variant LOW 3327T>C Ala1109Ala
M0135193 LAELIILP_00007 6362 4 Oral 0.57 protein_coding missense_variant MODERATE 3120C>A Asp1040Glu
M0135194 LAELIILP_00007 6374 3 Oral 0.43 protein_coding synonymous_variant LOW 3108T>C Gly1036Gly
M0135195 LAELIILP_00007 6491 4 Oral 0.57 protein_coding synonymous_variant LOW 2991A>T Thr997Thr
M0135196 LAELIILP_00007 6527 3 Oral 0.43 protein_coding missense_variant MODERATE 2955A>G Ile985Met
M0135197 LAELIILP_00007 6635 4 Oral 0.57 protein_coding synonymous_variant LOW 2847C>T Asn949Asn
M0135198 LAELIILP_00007 6686 3 Oral 0.43 protein_coding synonymous_variant LOW 2796T>C Gly932Gly
M0135199 LAELIILP_00007 6995 4 Oral 0.57 protein_coding synonymous_variant LOW 2487C>T Gly829Gly
M0135200 LAELIILP_00007 7082 4 Oral 0.57 protein_coding synonymous_variant LOW 2400C>T Ala800Ala
M0135201 LAELIILP_00007 7529 3 Oral 0.43 protein_coding synonymous_variant LOW 1953G>T Thr651Thr
M0135202 LAELIILP_00007 7688 3 Oral 0.43 protein_coding synonymous_variant LOW 1794G>A Glu598Glu
M0135203 LAELIILP_00007 7700 3 Oral 0.43 protein_coding synonymous_variant LOW 1782A>C Ile594Ile
M0135204 LAELIILP_00007 8173 4 Oral 0.57 protein_coding synonymous_variant LOW 1309C>T Leu437Leu
M0135205 LAELIILP_00007 8351 3 Oral 0.43 protein_coding synonymous_variant LOW 1131T>C Asp377Asp
M0135206 LAELIILP_00007 8369 4 Oral 0.57 protein_coding synonymous_variant LOW 1113T>C Val371Val
M0135207 LAELIILP_00007 8423 3 Oral 0.43 protein_coding synonymous_variant LOW 1059G>A Pro353Pro
M0135208 LAELIILP_00007 8444 4 Oral 0.57 protein_coding synonymous_variant LOW 1038C>A Thr346Thr
M0135209 LAELIILP_00007 8507 3 Oral 0.43 protein_coding synonymous_variant LOW 975A>T Pro325Pro
M0135210 LAELIILP_00007 8569 4 Oral 0.57 protein_coding missense_variant MODERATE 913A>G Ile305Val
M0135211 LAELIILP_00007 8593 4 Oral 0.57 protein_coding missense_variant MODERATE 889T>C Phe297Leu
M0135212 LAELIILP_00007 8765 3 Oral 0.43 protein_coding synonymous_variant LOW 717A>T Gly239Gly
M0135213 LAELIILP_00007 9188 5 Oral 0.71 protein_coding missense_variant MODERATE 294C>A Asn98Lys
M0135214 LAELIILP_00007 9278 3 Oral 0.43 protein_coding synonymous_variant LOW 204C>T Ala68Ala
M0135215 LAELIILP_00007 9285 5 Oral 0.71 protein_coding missense_variant MODERATE 197G>A Ser66Asn
M0135216 LAELIILP_00007 9302 3 Oral 0.43 protein_coding synonymous_variant LOW 180C>T Asp60Asp
M0135217 LAELIILP_00007 9359 3 Oral 0.43 protein_coding missense_variant MODERATE 123C>A Ser41Arg
M0135218 LAELIILP_00007 9404 3 Oral 0.43 protein_coding synonymous_variant LOW 78C>T Asn26Asn
M0135219 LAELIILP_00006 9564 5 Oral 0.71 protein_coding upstream_gene_variant MODIFIER -4268G>A None
M0135220 LAELIILP_00008 11734 3 Oral 0.43 protein_coding missense_variant MODERATE 2855C>G Ala952Gly
M0135221 LAELIILP_00008 11757 3 Oral 0.43 protein_coding synonymous_variant LOW 2832T>C Ala944Ala
M0135222 LAELIILP_00008 11796 3 Oral 0.43 protein_coding synonymous_variant LOW 2793T>C Asp931Asp
M0135223 LAELIILP_00008 11829 3 Oral 0.43 protein_coding synonymous_variant LOW 2760T>C Phe920Phe
M0135224 LAELIILP_00008 12606 3 Oral 0.43 protein_coding synonymous_variant LOW 1983T>C Ile661Ile
M0135225 LAELIILP_00008 12636 3 Oral 0.43 protein_coding synonymous_variant LOW 1953C>T Ser651Ser
M0135226 LAELIILP_00008 13188 3 Oral 0.43 protein_coding synonymous_variant LOW 1401A>G Gln467Gln
M0135227 LAELIILP_00008 13383 3 Oral 0.43 protein_coding synonymous_variant LOW 1206T>C Asp402Asp
M0135228 LAELIILP_00008 13638 3 Oral 0.43 protein_coding synonymous_variant LOW 951G>A Thr317Thr
M0135229 LAELIILP_00008 13857 3 Oral 0.43 protein_coding synonymous_variant LOW 732C>T Arg244Arg
M0135230 LAELIILP_00008 14484 3 Oral 0.43 protein_coding synonymous_variant LOW 105A>C Ala35Ala
M0135231 LAELIILP_00007 5855 3 Oral 0.43 protein_coding missense_variant MODERATE 3627A>T Leu1209Phe
M0135232 LAELIILP_00007 5857 3 Oral 0.43 protein_coding synonymous_variant LOW 3625T>C Leu1209Leu
M0135233 LAELIILP_00007 5858 3 Oral 0.43 protein_coding synonymous_variant LOW 3624A>G Pro1208Pro
M0135234 LAELIILP_00007 5918 3 Oral 0.43 protein_coding synonymous_variant LOW 3564T>C Asp1188Asp
M0135235 LAELIILP_00007 7316 3 Oral 0.43 protein_coding synonymous_variant LOW 2166A>C Arg722Arg
M0135236 LAELIILP_00007 7573 3 Oral 0.43 protein_coding missense_variant MODERATE 1909A>C Met637Leu
M0135237 LAELIILP_00006 9531 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -4235G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
LAELIILP_00008 QEM33029.1|GH70 99.9 0 1 1441 1 0.9945





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term