Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3318
  Reference Plasmid   MGYG000298345__MGYG000298345_176
  Reference Plasmid Size   25460
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0135298 AJNOEAIB_00003 401 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2763T>C None
M0135299 AJNOEAIB_00003 497 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2667C>T None
M0135300 AJNOEAIB_00003 515 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2649G>A None
M0135301 AJNOEAIB_00003 806 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2358G>T None
M0135302 AJNOEAIB_00003 830 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2334A>G None
M0135303 AJNOEAIB_00003 890 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2274T>C None
M0135304 AJNOEAIB_00003 1027 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2137T>G None
M0135305 AJNOEAIB_00003 1104 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2060T>G None
M0135306 AJNOEAIB_00001 2008 3 Oral 0.75 protein_coding synonymous_variant LOW 225C>G Val75Val
M0135307 AJNOEAIB_00001 2115 3 Oral 0.75 protein_coding synonymous_variant LOW 118C>T Leu40Leu
M0135308 AJNOEAIB_00001 2122 3 Oral 0.75 protein_coding missense_variant MODERATE 111G>A Met37Ile
M0135309 AJNOEAIB_00002 2278 3 Oral 0.75 protein_coding missense_variant MODERATE 779T>A Val260Glu
M0135310 AJNOEAIB_00002 2328 3 Oral 0.75 protein_coding synonymous_variant LOW 729A>G Ala243Ala
M0135311 AJNOEAIB_00002 2588 3 Oral 0.75 protein_coding synonymous_variant LOW 469T>C Leu157Leu
M0135312 AJNOEAIB_00002 2683 3 Oral 0.75 protein_coding missense_variant MODERATE 374A>G His125Arg
M0135313 AJNOEAIB_00002 2745 3 Oral 0.75 protein_coding missense_variant MODERATE 312T>A Asp104Glu
M0135314 AJNOEAIB_00002 2868 3 Oral 0.75 protein_coding synonymous_variant LOW 189A>G Lys63Lys
M0135315 AJNOEAIB_00002 2984 3 Oral 0.75 protein_coding missense_variant MODERATE 73A>G Ile25Val
M0135316 AJNOEAIB_00001 3080 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -848T>A None
M0135317 AJNOEAIB_00001 3090 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -858C>T None
M0135318 AJNOEAIB_00003 3337 3 Oral 0.75 protein_coding synonymous_variant LOW 174A>T Ser58Ser
M0135319 AJNOEAIB_00003 3358 3 Oral 0.75 protein_coding synonymous_variant LOW 195A>T Ile65Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
AJNOEAIB_00007 QUB57135.1|GH95 97.4 0 1 1163 1 1
AJNOEAIB_00008 QUB59983.1|GH2 97.4 0 20 1272 0.9851 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term