Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3319
  Reference Plasmid   MGYG000298346__MGYG000298346_10
  Reference Plasmid Size   68360
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0135320 OEHPMFCH_00004 7111 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -3890T>C None
M0135321 OEHPMFCH_00004 7143 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -3922G>A None
M0135322 OEHPMFCH_00008 7561 3 Oral 0.43 protein_coding synonymous_variant LOW 96T>C His32His
M0135323 OEHPMFCH_00008 7604 3 Oral 0.43 protein_coding missense_variant MODERATE 139G>C Glu47Gln
M0135324 OEHPMFCH_00008 7723 3 Oral 0.43 protein_coding synonymous_variant LOW 258C>T Ser86Ser
M0135325 OEHPMFCH_00009 8001 3 Oral 0.43 protein_coding synonymous_variant LOW 153A>G Glu51Glu
M0135326 OEHPMFCH_00006 5359 3 Oral 0.43 protein_coding synonymous_variant LOW 1332G>T Gly444Gly
M0135327 OEHPMFCH_00006 5458 3 Oral 0.43 protein_coding synonymous_variant LOW 1233T>C His411His
M0135328 OEHPMFCH_00006 5629 3 Oral 0.43 protein_coding synonymous_variant LOW 1062C>T Asp354Asp
M0135329 OEHPMFCH_00006 5662 3 Oral 0.43 protein_coding synonymous_variant LOW 1029A>G Leu343Leu
M0135330 OEHPMFCH_00006 5664 3 Oral 0.43 protein_coding synonymous_variant LOW 1027C>T Leu343Leu
M0135331 OEHPMFCH_00006 5686 3 Oral 0.43 protein_coding synonymous_variant LOW 1005A>G Val335Val
M0135332 OEHPMFCH_00006 5758 3 Oral 0.43 protein_coding synonymous_variant LOW 933C>T Asn311Asn
M0135333 OEHPMFCH_00006 5767 3 Oral 0.43 protein_coding synonymous_variant LOW 924C>A Ser308Ser
M0135334 OEHPMFCH_00006 5818 3 Oral 0.43 protein_coding synonymous_variant LOW 873T>C Thr291Thr
M0135335 OEHPMFCH_00006 5820 3 Oral 0.43 protein_coding missense_variant MODERATE 871A>G Thr291Ala
M0135336 OEHPMFCH_00006 5860 3 Oral 0.43 protein_coding synonymous_variant LOW 831G>T Ser277Ser
M0135337 OEHPMFCH_00006 5875 3 Oral 0.43 protein_coding synonymous_variant LOW 816T>C Arg272Arg
M0135338 OEHPMFCH_00006 5988 3 Oral 0.43 protein_coding synonymous_variant LOW 703C>T Leu235Leu
M0135339 OEHPMFCH_00006 6033 3 Oral 0.43 protein_coding synonymous_variant LOW 658T>C Leu220Leu
M0135340 OEHPMFCH_00006 6113 3 Oral 0.43 protein_coding missense_variant MODERATE 578A>G His193Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term