Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C31
  Reference Plasmid   MGYG000298420__MGYG000298420_78
  Reference Plasmid Size   10467
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0135421 KGNDBKKK_00009 7711 3 Oral 0.50 protein_coding synonymous_variant LOW 978C>T Arg326Arg
M0135422 KGNDBKKK_00009 7726 3 Oral 0.50 protein_coding synonymous_variant LOW 963C>G Val321Val
M0135423 KGNDBKKK_00009 7729 3 Oral 0.50 protein_coding synonymous_variant LOW 960C>T Asn320Asn
M0135424 KGNDBKKK_00009 7762 3 Oral 0.50 protein_coding synonymous_variant LOW 927A>C Thr309Thr
M0135425 KGNDBKKK_00009 7774 3 Oral 0.50 protein_coding synonymous_variant LOW 915T>C Val305Val
M0135426 KGNDBKKK_00009 7783 3 Oral 0.50 protein_coding synonymous_variant LOW 906T>C Leu302Leu
M0135427 KGNDBKKK_00009 7843 3 Oral 0.50 protein_coding synonymous_variant LOW 846G>A Arg282Arg
M0135428 KGNDBKKK_00009 7930 4 Oral 0.67 protein_coding synonymous_variant LOW 759G>A Arg253Arg
M0135429 KGNDBKKK_00009 7957 3 Oral 0.50 protein_coding synonymous_variant LOW 732T>C Phe244Phe
M0135430 KGNDBKKK_00009 7990 4 Oral 0.67 protein_coding synonymous_variant LOW 699A>C Leu233Leu
M0135431 KGNDBKKK_00009 8050 3 Oral 0.50 protein_coding synonymous_variant LOW 639T>C Gly213Gly
M0135432 KGNDBKKK_00009 8065 3 Oral 0.50 protein_coding synonymous_variant LOW 624T>C Ile208Ile
M0135433 KGNDBKKK_00009 8141 4 Oral 0.67 protein_coding missense_variant MODERATE 548T>C Val183Ala
M0135434 KGNDBKKK_00009 8146 4 Oral 0.67 protein_coding synonymous_variant LOW 543C>A Leu181Leu
M0135435 KGNDBKKK_00009 8587 4 Oral 0.67 protein_coding synonymous_variant LOW 102C>T Ser34Ser
M0135436 KGNDBKKK_00009 8677 4 Oral 0.67 protein_coding missense_variant MODERATE 12A>T Lys4Asn
M0135437 KGNDBKKK_00010 8778 4 Oral 0.67 protein_coding synonymous_variant LOW 1464A>G Glu488Glu
M0135438 KGNDBKKK_00010 8814 3 Oral 0.50 protein_coding synonymous_variant LOW 1428T>C Ser476Ser
M0135439 KGNDBKKK_00010 8835 3 Oral 0.50 protein_coding synonymous_variant LOW 1407T>C Asp469Asp
M0135440 KGNDBKKK_00010 8838 4 Oral 0.67 protein_coding missense_variant MODERATE 1404A>G Ile468Met
M0135441 KGNDBKKK_00010 8883 3 Oral 0.50 protein_coding synonymous_variant LOW 1359C>T Gly453Gly
M0135442 KGNDBKKK_00010 9609 4 Oral 0.67 protein_coding synonymous_variant LOW 633T>C Ala211Ala
M0135443 KGNDBKKK_00010 9648 4 Oral 0.67 protein_coding synonymous_variant LOW 594T>C Asp198Asp
M0135444 KGNDBKKK_00010 9855 3 Oral 0.50 protein_coding synonymous_variant LOW 387A>G Arg129Arg
M0135445 KGNDBKKK_00010 9918 4 Oral 0.67 protein_coding synonymous_variant LOW 324A>G Lys108Lys
M0135446 KGNDBKKK_00005 10427 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -4994T>C None
M0135447 KGNDBKKK_00009 8449 3 Oral 0.50 protein_coding synonymous_variant LOW 240C>T Ile80Ile
M0135448 KGNDBKKK_00009 8458 3 Oral 0.50 protein_coding synonymous_variant LOW 231T>C Gly77Gly
M0135449 KGNDBKKK_00009 8669 3 Oral 0.50 protein_coding missense_variant MODERATE 20C>T Ser7Leu
M0135450 KGNDBKKK_00003 8734 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -4709T>A None
M0135451 KGNDBKKK_00010 9597 3 Oral 0.50 protein_coding synonymous_variant LOW 645G>A Glu215Glu
M0141401 KGNDBKKK_00009 7747 3 Vaginal 0.60 protein_coding synonymous_variant LOW 942A>G Ala314Ala
M0141402 KGNDBKKK_00009 7930 3 Vaginal 0.60 protein_coding synonymous_variant LOW 759G>A Arg253Arg
M0141403 KGNDBKKK_00009 7957 3 Vaginal 0.60 protein_coding synonymous_variant LOW 732T>C Phe244Phe
M0141404 KGNDBKKK_00009 7990 4 Vaginal 0.80 protein_coding synonymous_variant LOW 699A>T Leu233Leu
M0141405 KGNDBKKK_00009 8002 3 Vaginal 0.60 protein_coding synonymous_variant LOW 687G>A Leu229Leu
M0141406 KGNDBKKK_00009 8004 3 Vaginal 0.60 protein_coding synonymous_variant LOW 685T>C Leu229Leu
M0141407 KGNDBKKK_00009 8050 4 Vaginal 0.80 protein_coding synonymous_variant LOW 639T>C Gly213Gly
M0141408 KGNDBKKK_00009 8065 4 Vaginal 0.80 protein_coding synonymous_variant LOW 624T>C Ile208Ile
M0141409 KGNDBKKK_00009 8141 4 Vaginal 0.80 protein_coding missense_variant MODERATE 548T>C Val183Ala
M0141410 KGNDBKKK_00009 8158 3 Vaginal 0.60 protein_coding synonymous_variant LOW 531C>A Ala177Ala
M0141411 KGNDBKKK_00010 9018 3 Vaginal 0.60 protein_coding synonymous_variant LOW 1224T>C Asp408Asp
M0141412 KGNDBKKK_00010 9048 3 Vaginal 0.60 protein_coding synonymous_variant LOW 1194T>G Thr398Thr
M0141413 KGNDBKKK_00010 9111 3 Vaginal 0.60 protein_coding synonymous_variant LOW 1131A>G Arg377Arg
M0141414 KGNDBKKK_00010 9147 3 Vaginal 0.60 protein_coding synonymous_variant LOW 1095C>A Thr365Thr
M0141415 KGNDBKKK_00010 9156 3 Vaginal 0.60 protein_coding synonymous_variant LOW 1086G>A Leu362Leu
M0141416 KGNDBKKK_00010 9158 3 Vaginal 0.60 protein_coding synonymous_variant LOW 1084C>T Leu362Leu
M0141417 KGNDBKKK_00010 9171 3 Vaginal 0.60 protein_coding synonymous_variant LOW 1071T>A Ala357Ala
M0141418 KGNDBKKK_00010 9300 3 Vaginal 0.60 protein_coding synonymous_variant LOW 942T>A Ile314Ile
M0141419 KGNDBKKK_00010 9312 3 Vaginal 0.60 protein_coding synonymous_variant LOW 930A>G Leu310Leu
M0141420 KGNDBKKK_00010 9314 3 Vaginal 0.60 protein_coding synonymous_variant LOW 928T>C Leu310Leu
M0141421 KGNDBKKK_00010 9488 4 Vaginal 0.80 protein_coding synonymous_variant LOW 754T>C Leu252Leu
M0141422 KGNDBKKK_00010 9495 4 Vaginal 0.80 protein_coding synonymous_variant LOW 747A>G Glu249Glu
M0141423 KGNDBKKK_00010 9510 4 Vaginal 0.80 protein_coding synonymous_variant LOW 732T>C Ala244Ala
M0141424 KGNDBKKK_00010 9597 4 Vaginal 0.80 protein_coding synonymous_variant LOW 645G>A Glu215Glu
M0141425 KGNDBKKK_00010 9609 4 Vaginal 0.80 protein_coding synonymous_variant LOW 633T>C Ala211Ala
M0141426 KGNDBKKK_00010 9648 4 Vaginal 0.80 protein_coding synonymous_variant LOW 594T>C Asp198Asp
M0141427 KGNDBKKK_00010 9702 3 Vaginal 0.60 protein_coding synonymous_variant LOW 540T>C Cys180Cys
M0141428 KGNDBKKK_00010 9771 3 Vaginal 0.60 protein_coding synonymous_variant LOW 471C>T Tyr157Tyr
M0141429 KGNDBKKK_00010 9855 4 Vaginal 0.80 protein_coding synonymous_variant LOW 387A>G Arg129Arg
M0141430 KGNDBKKK_00010 9918 4 Vaginal 0.80 protein_coding synonymous_variant LOW 324A>G Lys108Lys
M0141431 KGNDBKKK_00010 10011 4 Vaginal 0.80 protein_coding synonymous_variant LOW 231T>C Val77Val
M0141432 KGNDBKKK_00010 10092 4 Vaginal 0.80 protein_coding synonymous_variant LOW 150T>C Thr50Thr
M0141433 KGNDBKKK_00010 10095 4 Vaginal 0.80 protein_coding synonymous_variant LOW 147G>A Glu49Glu
M0141434 KGNDBKKK_00010 10149 3 Vaginal 0.60 protein_coding synonymous_variant LOW 93T>C Tyr31Tyr
M0141435 KGNDBKKK_00010 10164 3 Vaginal 0.60 protein_coding synonymous_variant LOW 78G>T Leu26Leu
M0141436 KGNDBKKK_00005 10397 3 Vaginal 0.60 protein_coding upstream_gene_variant MODIFIER -4964C>T None
M0141437 KGNDBKKK_00009 7834 3 Vaginal 0.60 protein_coding synonymous_variant LOW 855A>G Ala285Ala
M0141438 KGNDBKKK_00009 8188 3 Vaginal 0.60 protein_coding synonymous_variant LOW 501T>C Arg167Arg
M0141439 KGNDBKKK_00010 9543 3 Vaginal 0.60 protein_coding synonymous_variant LOW 699T>A Pro233Pro
M0141440 KGNDBKKK_00010 9897 3 Vaginal 0.60 protein_coding synonymous_variant LOW 345C>T Gly115Gly
M0141441 KGNDBKKK_00005 10267 3 Vaginal 0.60 protein_coding upstream_gene_variant MODIFIER -4834G>A None
M0141442 KGNDBKKK_00005 10322 3 Vaginal 0.60 protein_coding upstream_gene_variant MODIFIER -4889G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term