Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3332
  Reference Plasmid   MGYG000298579__MGYG000298579_11
  Reference Plasmid Size   40989
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0135568 MELIHADL_00017 24812 3 Oral 0.38 protein_coding synonymous_variant LOW 957C>T Tyr319Tyr
M0135569 MELIHADL_00017 25382 3 Oral 0.38 protein_coding synonymous_variant LOW 1527C>T Asp509Asp
M0135570 MELIHADL_00017 25383 3 Oral 0.38 protein_coding synonymous_variant LOW 1528C>T Leu510Leu
M0135571 MELIHADL_00017 25807 3 Oral 0.38 protein_coding missense_variant MODERATE 1952A>C His651Pro
M0135572 MELIHADL_00017 25889 3 Oral 0.38 protein_coding synonymous_variant LOW 2034C>A Arg678Arg
M0135573 MELIHADL_00017 26021 3 Oral 0.38 protein_coding synonymous_variant LOW 2166A>T Thr722Thr
M0135574 MELIHADL_00017 26180 3 Oral 0.38 protein_coding synonymous_variant LOW 2325T>A Ala775Ala
M0135575 MELIHADL_00017 26221 3 Oral 0.38 protein_coding missense_variant MODERATE 2366G>A Gly789Glu
M0135576 MELIHADL_00017 26262 3 Oral 0.38 protein_coding missense_variant MODERATE 2407T>C Phe803Leu
M0135577 MELIHADL_00017 26363 3 Oral 0.38 protein_coding synonymous_variant LOW 2508C>T His836His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
MELIHADL_00013 VEH15533.1|GH25 83.9 8.99e-192 1 286 1 0.9965
MELIHADL_00024 VEH15543.1|CE11 94.8 0 1 463 1 1
MELIHADL_00027 VEH15546.1|GT51 91.2 0 1 850 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term