Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3335
  Reference Plasmid   MGYG000298647__MGYG000298647_59
  Reference Plasmid Size   14021
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0135762 OIMONJDD_00005 5115 3 Oral 0.33 protein_coding missense_variant MODERATE 598T>C Tyr200His
M0135763 OIMONJDD_00005 5278 3 Oral 0.33 protein_coding missense_variant MODERATE 435T>A His145Gln
M0135764 OIMONJDD_00005 5299 3 Oral 0.33 protein_coding synonymous_variant LOW 414A>C Thr138Thr
M0135765 OIMONJDD_00005 5302 3 Oral 0.33 protein_coding synonymous_variant LOW 411T>C Ile137Ile
M0135766 OIMONJDD_00005 5305 3 Oral 0.33 protein_coding synonymous_variant LOW 408C>T Ser136Ser
M0135767 OIMONJDD_00005 5326 3 Oral 0.33 protein_coding synonymous_variant LOW 387G>A Glu129Glu
M0135768 OIMONJDD_00005 5638 4 Oral 0.44 protein_coding synonymous_variant LOW 75A>G Gln25Gln
M0135769 OIMONJDD_00005 5694 3 Oral 0.33 protein_coding missense_variant MODERATE 19A>G Thr7Ala
M0135770 OIMONJDD_00006 5742 4 Oral 0.44 protein_coding synonymous_variant LOW 1143A>T Ser381Ser
M0135771 OIMONJDD_00006 5787 3 Oral 0.33 protein_coding synonymous_variant LOW 1098C>T Arg366Arg
M0135772 OIMONJDD_00006 5912 4 Oral 0.44 protein_coding synonymous_variant LOW 973C>T Leu325Leu
M0135773 OIMONJDD_00006 6099 3 Oral 0.33 protein_coding synonymous_variant LOW 786C>T Thr262Thr
M0135774 OIMONJDD_00006 6131 4 Oral 0.44 protein_coding missense_variant MODERATE 754A>T Ser252Cys
M0135775 OIMONJDD_00006 6232 3 Oral 0.33 protein_coding missense_variant MODERATE 653C>A Thr218Lys
M0135776 OIMONJDD_00006 6267 3 Oral 0.33 protein_coding synonymous_variant LOW 618T>C Arg206Arg
M0135777 OIMONJDD_00006 6282 3 Oral 0.33 protein_coding synonymous_variant LOW 603C>T Gly201Gly
M0135778 OIMONJDD_00006 6363 3 Oral 0.33 protein_coding missense_variant MODERATE 522A>G Ile174Met
M0135779 OIMONJDD_00006 6365 3 Oral 0.33 protein_coding missense_variant MODERATE 520A>G Ile174Val
M0135780 OIMONJDD_00006 6395 3 Oral 0.33 protein_coding missense_variant MODERATE 490G>C Asp164His
M0135781 OIMONJDD_00006 6396 3 Oral 0.33 protein_coding synonymous_variant LOW 489A>G Gly163Gly
M0135782 OIMONJDD_00006 6438 3 Oral 0.33 protein_coding synonymous_variant LOW 447C>T Ala149Ala
M0135783 OIMONJDD_00006 6626 4 Oral 0.44 protein_coding missense_variant MODERATE 259C>T Leu87Phe
M0135784 OIMONJDD_00006 6752 3 Oral 0.33 protein_coding missense_variant MODERATE 133A>G Lys45Glu
M0135785 OIMONJDD_00006 6858 4 Oral 0.44 protein_coding synonymous_variant LOW 27T>C Val9Val
M0135786 OIMONJDD_00007 7086 4 Oral 0.44 protein_coding synonymous_variant LOW 1167A>T Thr389Thr
M0135787 OIMONJDD_00007 7107 4 Oral 0.44 protein_coding synonymous_variant LOW 1146T>C Gly382Gly
M0135788 OIMONJDD_00007 7299 3 Oral 0.33 protein_coding synonymous_variant LOW 954T>G Ala318Ala
M0135789 OIMONJDD_00007 7320 3 Oral 0.33 protein_coding synonymous_variant LOW 933A>G Lys311Lys
M0135790 OIMONJDD_00007 7331 3 Oral 0.33 protein_coding missense_variant MODERATE 922A>G Ile308Val
M0135791 OIMONJDD_00007 7350 3 Oral 0.33 protein_coding synonymous_variant LOW 903G>A Ala301Ala
M0135792 OIMONJDD_00007 7521 3 Oral 0.33 protein_coding synonymous_variant LOW 732G>A Glu244Glu
M0135793 OIMONJDD_00007 7614 3 Oral 0.33 protein_coding synonymous_variant LOW 639A>G Glu213Glu
M0135794 OIMONJDD_00007 7782 4 Oral 0.44 protein_coding synonymous_variant LOW 471T>A Leu157Leu
M0135795 OIMONJDD_00007 7827 3 Oral 0.33 protein_coding synonymous_variant LOW 426C>T Pro142Pro
M0135796 OIMONJDD_00007 7848 3 Oral 0.33 protein_coding synonymous_variant LOW 405C>A Gly135Gly
M0135797 OIMONJDD_00007 7974 3 Oral 0.33 protein_coding synonymous_variant LOW 279G>T Gly93Gly
M0135798 OIMONJDD_00006 5838 3 Oral 0.33 protein_coding synonymous_variant LOW 1047T>C Asn349Asn
M0135799 OIMONJDD_00006 6522 3 Oral 0.33 protein_coding synonymous_variant LOW 363A>T Thr121Thr
M0135800 OIMONJDD_00007 7155 3 Oral 0.33 protein_coding synonymous_variant LOW 1098C>T Tyr366Tyr
M0135801 OIMONJDD_00007 7197 3 Oral 0.33 protein_coding synonymous_variant LOW 1056C>T Asp352Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
OIMONJDD_00006 EFC71566.1|GT2 90 6.87e-258 1 391 1 0.9974





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term