Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3337
  Reference Plasmid   MGYG000298704__MGYG000298704_70
  Reference Plasmid Size   4637
  Reference Plasmid GC Content   0.48
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0135931 KFEOPJOI_00002 1769 3 Oral 0.38 protein_coding missense_variant MODERATE 1244C>T Thr415Ile
M0135932 KFEOPJOI_00002 1770 3 Oral 0.38 protein_coding synonymous_variant LOW 1245C>T Thr415Thr
M0135933 KFEOPJOI_00002 1782 3 Oral 0.38 protein_coding synonymous_variant LOW 1257C>T Gly419Gly
M0135934 KFEOPJOI_00002 1824 4 Oral 0.50 protein_coding synonymous_variant LOW 1299T>C Asp433Asp
M0135935 KFEOPJOI_00002 1977 3 Oral 0.38 protein_coding synonymous_variant LOW 1452T>C Asp484Asp
M0135936 KFEOPJOI_00002 2008 3 Oral 0.38 protein_coding missense_variant MODERATE 1483G>T Ala495Ser
M0135937 KFEOPJOI_00002 2010 3 Oral 0.38 protein_coding synonymous_variant LOW 1485A>G Ala495Ala
M0135938 KFEOPJOI_00002 2013 3 Oral 0.38 protein_coding synonymous_variant LOW 1488G>A Leu496Leu
M0135939 KFEOPJOI_00002 2073 3 Oral 0.38 protein_coding synonymous_variant LOW 1548T>G Ala516Ala
M0135940 KFEOPJOI_00002 2080 5 Oral 0.63 protein_coding missense_variant MODERATE 1555A>C Lys519Gln
M0135941 KFEOPJOI_00002 2100 6 Oral 0.75 protein_coding synonymous_variant LOW 1575T>C Gly525Gly
M0135942 KFEOPJOI_00002 2259 5 Oral 0.63 protein_coding synonymous_variant LOW 1734C>T Val578Val
M0135943 KFEOPJOI_00002 2271 4 Oral 0.50 protein_coding synonymous_variant LOW 1746T>C Arg582Arg
M0135944 KFEOPJOI_00003 2479 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -201T>C None
M0135945 KFEOPJOI_00003 2651 4 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -29C>T None
M0135946 KFEOPJOI_00003 2733 4 Oral 0.50 protein_coding synonymous_variant LOW 54C>T Asn18Asn
M0135947 KFEOPJOI_00003 2763 7 Oral 0.88 protein_coding synonymous_variant LOW 84C>A Gly28Gly
M0135948 KFEOPJOI_00003 2769 7 Oral 0.88 protein_coding synonymous_variant LOW 90T>C Arg30Arg
M0135949 KFEOPJOI_00003 2775 3 Oral 0.38 protein_coding synonymous_variant LOW 96C>T Leu32Leu
M0135950 KFEOPJOI_00003 2787 4 Oral 0.50 protein_coding synonymous_variant LOW 108C>T His36His
M0135951 KFEOPJOI_00003 2800 4 Oral 0.50 protein_coding missense_variant MODERATE 121G>A Ala41Thr
M0135952 KFEOPJOI_00003 2802 4 Oral 0.50 protein_coding synonymous_variant LOW 123C>T Ala41Ala
M0135953 KFEOPJOI_00003 2817 4 Oral 0.50 protein_coding synonymous_variant LOW 138T>G Arg46Arg
M0135954 KFEOPJOI_00002 1872 3 Oral 0.38 protein_coding synonymous_variant LOW 1347C>T Tyr449Tyr
M0135955 KFEOPJOI_00002 2099 4 Oral 0.50 protein_coding missense_variant MODERATE 1574G>A Gly525Asp
M0135956 KFEOPJOI_00003 2512 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -168C>T None
M0135957 KFEOPJOI_00003 3051 7 Oral 0.88 protein_coding synonymous_variant LOW 372G>C Arg124Arg
M0135958 KFEOPJOI_00004 3356 3 Oral 0.38 protein_coding synonymous_variant LOW 255C>A Ile85Ile
M0135959 KFEOPJOI_00004 3488 3 Oral 0.38 protein_coding missense_variant MODERATE 387A>C Lys129Asn
M0135960 KFEOPJOI_00004 3506 3 Oral 0.38 protein_coding synonymous_variant LOW 405C>T Asn135Asn
M0135961 KFEOPJOI_00005 3830 4 Oral 0.50 protein_coding synonymous_variant LOW 75A>G Glu25Glu
M0135962 KFEOPJOI_00005 3884 3 Oral 0.38 protein_coding synonymous_variant LOW 129A>G Ala43Ala
M0135963 KFEOPJOI_00005 3938 3 Oral 0.38 protein_coding synonymous_variant LOW 183G>A Glu61Glu
M0135964 KFEOPJOI_00005 3945 3 Oral 0.38 protein_coding missense_variant MODERATE 190A>G Lys64Glu
M0135965 KFEOPJOI_00005 3950 3 Oral 0.38 protein_coding synonymous_variant LOW 195A>G Gln65Gln
M0135966 KFEOPJOI_00005 4080 5 Oral 0.63 protein_coding synonymous_variant LOW 325T>C Leu109Leu
M0135967 KFEOPJOI_00005 4294 4 Oral 0.50 protein_coding missense_variant MODERATE 539T>C Met180Thr
M0135968 KFEOPJOI_00001 4393 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *3891A>G None
M0135969 KFEOPJOI_00001 4418 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *3916C>A None
M0135970 KFEOPJOI_00001 4424 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *3922C>A None
M0135971 KFEOPJOI_00001 4506 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *4004G>A None
M0135972 KFEOPJOI_00001 4510 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *4008T>C None
M0135973 KFEOPJOI_00001 342 3 Oral 0.38 protein_coding missense_variant MODERATE 59T>C Met20Thr
M0135974 KFEOPJOI_00003 2766 3 Oral 0.38 protein_coding synonymous_variant LOW 87T>C His29His
M0135975 KFEOPJOI_00003 2838 3 Oral 0.38 protein_coding synonymous_variant LOW 159A>G Thr53Thr
M0135976 KFEOPJOI_00003 2841 3 Oral 0.38 protein_coding synonymous_variant LOW 162C>T Asp54Asp
M0135977 KFEOPJOI_00003 2850 3 Oral 0.38 protein_coding synonymous_variant LOW 171T>C Asn57Asn
M0135978 KFEOPJOI_00003 2859 3 Oral 0.38 protein_coding synonymous_variant LOW 180A>G Lys60Lys
M0135979 KFEOPJOI_00004 3560 3 Oral 0.38 protein_coding synonymous_variant LOW 459A>G Glu153Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term