Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3340
  Reference Plasmid   MGYG000298771__MGYG000298771_254
  Reference Plasmid Size   3430
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0136229 OBIKGMFF_00001 59 5 Oral 1.00 protein_coding synonymous_variant LOW 9C>T Tyr3Tyr
M0136230 OBIKGMFF_00001 239 4 Oral 0.80 protein_coding synonymous_variant LOW 189A>T Pro63Pro
M0136231 OBIKGMFF_00001 296 5 Oral 1.00 protein_coding synonymous_variant LOW 246T>C Ser82Ser
M0136232 OBIKGMFF_00001 374 4 Oral 0.80 protein_coding synonymous_variant LOW 324T>C Phe108Phe
M0136233 OBIKGMFF_00001 460 4 Oral 0.80 protein_coding missense_variant MODERATE 410C>T Ala137Val
M0136234 OBIKGMFF_00001 530 5 Oral 1.00 protein_coding synonymous_variant LOW 480T>C Asn160Asn
M0136235 OBIKGMFF_00001 581 4 Oral 0.80 protein_coding synonymous_variant LOW 531T>C Thr177Thr
M0136236 OBIKGMFF_00001 650 3 Oral 0.60 protein_coding synonymous_variant LOW 600C>T Asn200Asn
M0136237 OBIKGMFF_00001 707 3 Oral 0.60 protein_coding synonymous_variant LOW 657T>C Ser219Ser
M0136238 OBIKGMFF_00001 743 4 Oral 0.80 protein_coding synonymous_variant LOW 693G>A Gly231Gly
M0136239 OBIKGMFF_00001 845 4 Oral 0.80 protein_coding synonymous_variant LOW 795G>C Gly265Gly
M0136240 OBIKGMFF_00001 1080 4 Oral 0.80 protein_coding missense_variant MODERATE 1030T>C Phe344Leu
M0136241 OBIKGMFF_00001 1092 4 Oral 0.80 protein_coding missense_variant MODERATE 1042A>G Lys348Glu
M0136242 OBIKGMFF_00002 1180 3 Oral 0.60 protein_coding missense_variant MODERATE 40G>A Ala14Thr
M0136243 OBIKGMFF_00002 1461 3 Oral 0.60 protein_coding synonymous_variant LOW 321T>C Asn107Asn
M0136244 OBIKGMFF_00002 1590 3 Oral 0.60 protein_coding synonymous_variant LOW 450A>T Ala150Ala
M0136245 OBIKGMFF_00002 1677 4 Oral 0.80 protein_coding synonymous_variant LOW 537C>T Ile179Ile
M0136246 OBIKGMFF_00002 1695 4 Oral 0.80 protein_coding synonymous_variant LOW 555C>T Pro185Pro
M0136247 OBIKGMFF_00002 1770 4 Oral 0.80 protein_coding synonymous_variant LOW 630T>C Asn210Asn
M0136248 OBIKGMFF_00002 1794 3 Oral 0.60 protein_coding synonymous_variant LOW 654G>A Lys218Lys
M0136249 OBIKGMFF_00002 1800 3 Oral 0.60 protein_coding synonymous_variant LOW 660A>T Thr220Thr
M0136250 OBIKGMFF_00002 1803 3 Oral 0.60 protein_coding synonymous_variant LOW 663T>A Ala221Ala
M0136251 OBIKGMFF_00002 2012 3 Oral 0.60 protein_coding missense_variant MODERATE 872T>C Val291Ala
M0136252 OBIKGMFF_00002 2055 3 Oral 0.60 protein_coding synonymous_variant LOW 915C>T Ile305Ile
M0136253 OBIKGMFF_00002 2142 3 Oral 0.60 protein_coding synonymous_variant LOW 1002A>C Thr334Thr
M0136254 OBIKGMFF_00002 2226 3 Oral 0.60 protein_coding synonymous_variant LOW 1086G>A Glu362Glu
M0136255 OBIKGMFF_00001 2477 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1362T>C None
M0136256 OBIKGMFF_00001 2492 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1377G>C None
M0136257 OBIKGMFF_00001 2567 4 Oral 0.80 protein_coding downstream_gene_variant MODIFIER *1452T>C None
M0136258 OBIKGMFF_00001 2637 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1522T>C None
M0136259 OBIKGMFF_00002 1851 3 Oral 0.60 protein_coding synonymous_variant LOW 711C>T Gly237Gly
M0136260 OBIKGMFF_00002 1857 3 Oral 0.60 protein_coding synonymous_variant LOW 717G>A Lys239Lys
M0136261 OBIKGMFF_00001 2850 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1735T>G None
M0136262 OBIKGMFF_00001 2931 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1816A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term