Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3342
  Reference Plasmid   MGYG000298772__MGYG000298772_303
  Reference Plasmid Size   6650
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0136276 KMNPCLCL_00002 3877 3 Oral 0.60 protein_coding synonymous_variant LOW 1575A>G Val525Val
M0136277 KMNPCLCL_00002 4045 3 Oral 0.60 protein_coding synonymous_variant LOW 1407T>C Tyr469Tyr
M0136278 KMNPCLCL_00002 4183 3 Oral 0.60 protein_coding synonymous_variant LOW 1269C>T Gly423Gly
M0136279 KMNPCLCL_00002 4237 3 Oral 0.60 protein_coding synonymous_variant LOW 1215C>T Phe405Phe
M0136280 KMNPCLCL_00002 4297 3 Oral 0.60 protein_coding synonymous_variant LOW 1155C>T Ser385Ser
M0136281 KMNPCLCL_00002 4774 3 Oral 0.60 protein_coding synonymous_variant LOW 678T>C Asp226Asp
M0136282 KMNPCLCL_00002 4825 3 Oral 0.60 protein_coding synonymous_variant LOW 627C>T Asn209Asn
M0136283 KMNPCLCL_00002 4849 3 Oral 0.60 protein_coding synonymous_variant LOW 603T>C Asp201Asp
M0136284 KMNPCLCL_00002 4903 3 Oral 0.60 protein_coding synonymous_variant LOW 549C>T Asn183Asn
M0136285 KMNPCLCL_00002 4905 3 Oral 0.60 protein_coding missense_variant MODERATE 547A>G Asn183Asp
M0136286 KMNPCLCL_00002 4938 3 Oral 0.60 protein_coding synonymous_variant LOW 514A>C Arg172Arg
M0136287 KMNPCLCL_00002 5255 3 Oral 0.60 protein_coding missense_variant MODERATE 197G>A Ser66Asn
M0136288 KMNPCLCL_00002 5372 3 Oral 0.60 protein_coding missense_variant MODERATE 80A>G Glu27Gly
M0136289 KMNPCLCL_00002 1429 4 Oral 0.80 protein_coding synonymous_variant LOW 4023T>A Val1341Val
M0136290 KMNPCLCL_00002 1590 4 Oral 0.80 protein_coding missense_variant MODERATE 3862A>G Ser1288Gly
M0136291 KMNPCLCL_00002 1603 4 Oral 0.80 protein_coding synonymous_variant LOW 3849G>A Gln1283Gln
M0136292 KMNPCLCL_00002 1852 3 Oral 0.60 protein_coding synonymous_variant LOW 3600G>A Ser1200Ser
M0136293 KMNPCLCL_00002 1876 3 Oral 0.60 protein_coding synonymous_variant LOW 3576C>T Asn1192Asn
M0136294 KMNPCLCL_00002 1885 3 Oral 0.60 protein_coding synonymous_variant LOW 3567T>C Thr1189Thr
M0136295 KMNPCLCL_00002 1918 3 Oral 0.60 protein_coding synonymous_variant LOW 3534T>C Asn1178Asn
M0136296 KMNPCLCL_00002 1925 3 Oral 0.60 protein_coding missense_variant MODERATE 3527T>C Val1176Ala
M0136297 KMNPCLCL_00002 1927 3 Oral 0.60 protein_coding synonymous_variant LOW 3525G>A Gly1175Gly
M0136298 KMNPCLCL_00002 1951 4 Oral 0.80 protein_coding synonymous_variant LOW 3501T>C Ser1167Ser
M0136299 KMNPCLCL_00002 1978 3 Oral 0.60 protein_coding synonymous_variant LOW 3474T>C Gly1158Gly
M0136300 KMNPCLCL_00002 2011 4 Oral 0.80 protein_coding synonymous_variant LOW 3441C>T Gly1147Gly
M0136301 KMNPCLCL_00002 2107 4 Oral 0.80 protein_coding synonymous_variant LOW 3345T>C Arg1115Arg
M0136302 KMNPCLCL_00002 2335 3 Oral 0.60 protein_coding synonymous_variant LOW 3117A>G Ala1039Ala
M0136303 KMNPCLCL_00002 2341 3 Oral 0.60 protein_coding synonymous_variant LOW 3111G>A Ser1037Ser
M0136304 KMNPCLCL_00002 2343 3 Oral 0.60 protein_coding missense_variant MODERATE 3109T>G Ser1037Ala
M0136305 KMNPCLCL_00002 2404 4 Oral 0.80 protein_coding synonymous_variant LOW 3048T>C Asp1016Asp
M0136306 KMNPCLCL_00002 2425 3 Oral 0.60 protein_coding synonymous_variant LOW 3027A>G Val1009Val
M0136307 KMNPCLCL_00002 2464 4 Oral 0.80 protein_coding synonymous_variant LOW 2988A>T Ile996Ile
M0136308 KMNPCLCL_00002 2479 4 Oral 0.80 protein_coding synonymous_variant LOW 2973A>G Lys991Lys
M0136309 KMNPCLCL_00002 2758 3 Oral 0.60 protein_coding synonymous_variant LOW 2694T>G Ser898Ser
M0136310 KMNPCLCL_00002 3139 3 Oral 0.60 protein_coding synonymous_variant LOW 2313T>A Pro771Pro
M0136311 KMNPCLCL_00002 3313 3 Oral 0.60 protein_coding synonymous_variant LOW 2139G>A Lys713Lys
M0136312 KMNPCLCL_00002 3315 3 Oral 0.60 protein_coding missense_variant MODERATE 2137A>C Lys713Gln
M0136313 KMNPCLCL_00002 3511 3 Oral 0.60 protein_coding synonymous_variant LOW 1941T>A Gly647Gly
M0136314 KMNPCLCL_00002 3532 3 Oral 0.60 protein_coding synonymous_variant LOW 1920A>C Gly640Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
KMNPCLCL_00002 EFC71803.1|GH2 96.1 0 1 1344 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term