Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3343
  Reference Plasmid   MGYG000298772__MGYG000298772_49
  Reference Plasmid Size   5045
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0136315 KBBEHPDK_00003 3585 3 Oral 0.50 protein_coding synonymous_variant LOW 657A>G Ala219Ala
M0136316 KBBEHPDK_00003 3639 3 Oral 0.50 protein_coding synonymous_variant LOW 603A>G Glu201Glu
M0136317 KBBEHPDK_00003 3648 3 Oral 0.50 protein_coding synonymous_variant LOW 594T>C Ala198Ala
M0136318 KBBEHPDK_00003 3657 3 Oral 0.50 protein_coding synonymous_variant LOW 585G>A Gln195Gln
M0136319 KBBEHPDK_00003 3669 3 Oral 0.50 protein_coding synonymous_variant LOW 573C>T His191His
M0136320 KBBEHPDK_00003 3690 3 Oral 0.50 protein_coding missense_variant MODERATE 552C>G Asp184Glu
M0136321 KBBEHPDK_00003 4008 3 Oral 0.50 protein_coding synonymous_variant LOW 234A>G Lys78Lys
M0136322 KBBEHPDK_00003 4028 3 Oral 0.50 protein_coding synonymous_variant LOW 214C>T Leu72Leu
M0136323 KBBEHPDK_00003 4029 3 Oral 0.50 protein_coding missense_variant MODERATE 213T>A Asp71Glu
M0136324 KBBEHPDK_00003 4054 3 Oral 0.50 protein_coding missense_variant MODERATE 188G>C Gly63Ala
M0136325 KBBEHPDK_00003 4055 3 Oral 0.50 protein_coding missense_variant MODERATE 187G>A Gly63Arg
M0136326 KBBEHPDK_00003 4060 3 Oral 0.50 protein_coding missense_variant MODERATE 182A>C Lys61Thr
M0136327 KBBEHPDK_00003 4143 3 Oral 0.50 protein_coding synonymous_variant LOW 99T>C Asp33Asp
M0136328 KBBEHPDK_00003 4152 3 Oral 0.50 protein_coding synonymous_variant LOW 90G>A Glu30Glu
M0136329 KBBEHPDK_00003 4173 3 Oral 0.50 protein_coding synonymous_variant LOW 69G>A Lys23Lys
M0136330 KBBEHPDK_00004 4325 3 Oral 0.50 protein_coding synonymous_variant LOW 714C>T Tyr238Tyr
M0136331 KBBEHPDK_00004 4351 3 Oral 0.50 protein_coding missense_variant MODERATE 688A>G Asn230Asp
M0136332 KBBEHPDK_00004 4454 3 Oral 0.50 protein_coding synonymous_variant LOW 585C>T Ile195Ile
M0136333 KBBEHPDK_00004 4546 3 Oral 0.50 protein_coding missense_variant MODERATE 493T>A Ser165Thr
M0136334 KBBEHPDK_00004 4862 3 Oral 0.50 protein_coding synonymous_variant LOW 177T>C His59His
M0136335 KBBEHPDK_00002 2838 3 Oral 0.50 protein_coding missense_variant MODERATE 214T>C Phe72Leu
M0136336 KBBEHPDK_00002 2929 3 Oral 0.50 protein_coding synonymous_variant LOW 123A>G Glu41Glu
M0136337 KBBEHPDK_00002 2940 3 Oral 0.50 protein_coding missense_variant MODERATE 112A>G Lys38Glu
M0136338 KBBEHPDK_00002 3028 3 Oral 0.50 protein_coding synonymous_variant LOW 24G>A Lys8Lys
M0136339 KBBEHPDK_00003 3318 3 Oral 0.50 protein_coding synonymous_variant LOW 924A>C Val308Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term