Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3354
  Reference Plasmid   MGYG000298844__MGYG000298844_232
  Reference Plasmid Size   3338
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0136585 NNOEHDNG_00001 141 3 Oral 1.00 protein_coding synonymous_variant LOW 1680A>T Ser560Ser
M0136586 NNOEHDNG_00001 234 3 Oral 1.00 protein_coding synonymous_variant LOW 1587T>C Ser529Ser
M0136587 NNOEHDNG_00001 280 3 Oral 1.00 protein_coding missense_variant MODERATE 1541G>A Ser514Asn
M0136588 NNOEHDNG_00001 293 3 Oral 1.00 protein_coding missense_variant MODERATE 1528C>T Pro510Ser
M0136589 NNOEHDNG_00001 297 3 Oral 1.00 protein_coding synonymous_variant LOW 1524T>C Ser508Ser
M0136590 NNOEHDNG_00001 312 3 Oral 1.00 protein_coding synonymous_variant LOW 1509A>G Lys503Lys
M0136591 NNOEHDNG_00001 324 3 Oral 1.00 protein_coding synonymous_variant LOW 1497A>G Gln499Gln
M0136592 NNOEHDNG_00001 342 3 Oral 1.00 protein_coding synonymous_variant LOW 1479G>C Arg493Arg
M0136593 NNOEHDNG_00001 474 3 Oral 1.00 protein_coding synonymous_variant LOW 1347A>G Leu449Leu
M0136594 NNOEHDNG_00001 488 3 Oral 1.00 protein_coding synonymous_variant LOW 1333T>C Leu445Leu
M0136595 NNOEHDNG_00001 498 3 Oral 1.00 protein_coding synonymous_variant LOW 1323G>T Thr441Thr
M0136596 NNOEHDNG_00001 546 3 Oral 1.00 protein_coding synonymous_variant LOW 1275A>C Pro425Pro
M0136597 NNOEHDNG_00001 666 3 Oral 1.00 protein_coding synonymous_variant LOW 1155T>A Thr385Thr
M0136598 NNOEHDNG_00001 690 3 Oral 1.00 protein_coding synonymous_variant LOW 1131C>T Asp377Asp
M0136599 NNOEHDNG_00001 946 3 Oral 1.00 protein_coding missense_variant MODERATE 875A>C Asp292Ala
M0136600 NNOEHDNG_00001 1038 3 Oral 1.00 protein_coding synonymous_variant LOW 783T>C Ala261Ala
M0136601 NNOEHDNG_00001 1089 3 Oral 1.00 protein_coding synonymous_variant LOW 732G>A Gly244Gly
M0136602 NNOEHDNG_00001 1122 3 Oral 1.00 protein_coding synonymous_variant LOW 699A>G Leu233Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term