Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3358
  Reference Plasmid   MGYG000298853__MGYG000298853_2
  Reference Plasmid Size   100140
  Reference Plasmid GC Content   0.49
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0136938 FBBOPHGL_00026 36348 3 Oral 0.50 protein_coding synonymous_variant LOW 720T>C Thr240Thr
M0136939 FBBOPHGL_00026 36680 3 Oral 0.50 protein_coding missense_variant MODERATE 388A>C Lys130Gln
M0136940 FBBOPHGL_00026 37008 3 Oral 0.50 protein_coding synonymous_variant LOW 60A>G Gln20Gln
M0136941 FBBOPHGL_00026 37014 3 Oral 0.50 protein_coding synonymous_variant LOW 54A>G Ala18Ala
M0136942 FBBOPHGL_00023 37190 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -4887A>G None
M0136943 FBBOPHGL_00028 38490 3 Oral 0.50 protein_coding synonymous_variant LOW 399T>C Asp133Asp
M0136944 FBBOPHGL_00028 38493 3 Oral 0.50 protein_coding synonymous_variant LOW 402T>C Asn134Asn
M0136945 FBBOPHGL_00028 38502 3 Oral 0.50 protein_coding synonymous_variant LOW 411A>C Ala137Ala
M0136946 FBBOPHGL_00028 38556 3 Oral 0.50 protein_coding synonymous_variant LOW 465C>T Ala155Ala
M0136947 FBBOPHGL_00028 38562 3 Oral 0.50 protein_coding synonymous_variant LOW 471G>C Thr157Thr
M0136948 FBBOPHGL_00028 38586 3 Oral 0.50 protein_coding synonymous_variant LOW 495C>G Ala165Ala
M0136949 FBBOPHGL_00028 38712 3 Oral 0.50 protein_coding synonymous_variant LOW 621A>G Ser207Ser
M0136950 FBBOPHGL_00028 39018 3 Oral 0.50 protein_coding synonymous_variant LOW 927A>G Thr309Thr
M0136951 FBBOPHGL_00028 39063 3 Oral 0.50 protein_coding synonymous_variant LOW 972C>A Ala324Ala
M0136952 FBBOPHGL_00028 39182 3 Oral 0.50 protein_coding missense_variant MODERATE 1091T>C Leu364Ser
M0136953 FBBOPHGL_00028 39300 3 Oral 0.50 protein_coding synonymous_variant LOW 1209T>C Asn403Asn
M0136954 FBBOPHGL_00029 39953 3 Oral 0.50 protein_coding synonymous_variant LOW 436T>C Leu146Leu
M0136955 FBBOPHGL_00029 39955 3 Oral 0.50 protein_coding missense_variant MODERATE 438G>C Leu146Phe
M0136956 FBBOPHGL_00029 39982 3 Oral 0.50 protein_coding synonymous_variant LOW 465C>T Arg155Arg
M0136957 FBBOPHGL_00029 40142 3 Oral 0.50 protein_coding missense_variant MODERATE 625A>G Ile209Val
M0136958 FBBOPHGL_00029 40183 3 Oral 0.50 protein_coding synonymous_variant LOW 666T>C Pro222Pro
M0136959 FBBOPHGL_00029 40195 3 Oral 0.50 protein_coding synonymous_variant LOW 678A>G Ala226Ala
M0136960 FBBOPHGL_00029 40210 3 Oral 0.50 protein_coding synonymous_variant LOW 693A>C Ile231Ile
M0136961 FBBOPHGL_00029 40213 3 Oral 0.50 protein_coding synonymous_variant LOW 696T>C Arg232Arg
M0136962 FBBOPHGL_00029 40249 3 Oral 0.50 protein_coding synonymous_variant LOW 732A>C Arg244Arg
M0136963 FBBOPHGL_00029 40432 3 Oral 0.50 protein_coding synonymous_variant LOW 915T>C Arg305Arg
M0136964 FBBOPHGL_00029 40606 3 Oral 0.50 protein_coding synonymous_variant LOW 1089C>T Pro363Pro
M0136965 FBBOPHGL_00030 40746 3 Oral 0.50 protein_coding missense_variant MODERATE 82G>A Val28Ile
M0136966 FBBOPHGL_00030 41021 3 Oral 0.50 protein_coding synonymous_variant LOW 357A>G Ala119Ala
M0136967 FBBOPHGL_00030 41132 3 Oral 0.50 protein_coding synonymous_variant LOW 468T>G Ala156Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FBBOPHGL_00027 UKK68365.1|GT2 82.3 7.01e-148 1 243 0.9759 0.9681





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term