Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3365
  Reference Plasmid   MGYG000298928__MGYG000298928_29
  Reference Plasmid Size   22350
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0137319 HHKBNLCE_00009 10780 4 Oral 1.00 protein_coding synonymous_variant LOW 219T>C Ser73Ser
M0137320 HHKBNLCE_00010 11157 4 Oral 1.00 protein_coding synonymous_variant LOW 1362C>T Tyr454Tyr
M0137321 HHKBNLCE_00010 11529 4 Oral 1.00 protein_coding synonymous_variant LOW 990A>C Gly330Gly
M0137322 HHKBNLCE_00010 11688 3 Oral 0.75 protein_coding synonymous_variant LOW 831T>C Ser277Ser
M0137323 HHKBNLCE_00010 11946 3 Oral 0.75 protein_coding synonymous_variant LOW 573A>G Glu191Glu
M0137324 HHKBNLCE_00011 12863 4 Oral 1.00 protein_coding synonymous_variant LOW 1222A>C Arg408Arg
M0137325 HHKBNLCE_00011 12885 3 Oral 0.75 protein_coding synonymous_variant LOW 1200C>T Asp400Asp
M0137326 HHKBNLCE_00011 13008 4 Oral 1.00 protein_coding synonymous_variant LOW 1077A>G Glu359Glu
M0137327 HHKBNLCE_00011 13788 3 Oral 0.75 protein_coding synonymous_variant LOW 297G>A Pro99Pro
M0137328 HHKBNLCE_00008 8550 3 Oral 0.75 protein_coding synonymous_variant LOW 1665G>A Glu555Glu
M0137329 HHKBNLCE_00008 8727 3 Oral 0.75 protein_coding synonymous_variant LOW 1488A>G Arg496Arg
M0137330 HHKBNLCE_00008 8943 3 Oral 0.75 protein_coding synonymous_variant LOW 1272T>C His424His
M0137331 HHKBNLCE_00008 9150 3 Oral 0.75 protein_coding synonymous_variant LOW 1065G>A Val355Val
M0137332 HHKBNLCE_00008 9180 3 Oral 0.75 protein_coding synonymous_variant LOW 1035T>C Cys345Cys
M0137333 HHKBNLCE_00008 10132 3 Oral 0.75 protein_coding missense_variant MODERATE 83A>G Asn28Ser
M0137334 HHKBNLCE_00009 10555 3 Oral 0.75 protein_coding missense_variant MODERATE 444T>G Asp148Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
HHKBNLCE_00004 QUI95814.1|GT113 100 7.32e-243 1 331 1 1
HHKBNLCE_00006 QUI95816.1|GT8 99.6 0 1 452 1 1
HHKBNLCE_00007 QUI95817.1|GT4 100 0 1 509 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term