Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3367
  Reference Plasmid   MGYG000298937__MGYG000298937_37
  Reference Plasmid Size   116430
  Reference Plasmid GC Content   0.48
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0137461 HPPEFDBK_00044 54547 3 Oral 0.33 protein_coding synonymous_variant LOW 5499A>G Thr1833Thr
M0137462 HPPEFDBK_00044 55297 3 Oral 0.33 protein_coding synonymous_variant LOW 6249C>A Arg2083Arg
M0137463 HPPEFDBK_00046 59407 3 Oral 0.33 protein_coding missense_variant MODERATE 617A>T Lys206Met
M0137464 HPPEFDBK_00052 64421 3 Oral 0.33 protein_coding missense_variant MODERATE 19A>G Ile7Val
M0137465 HPPEFDBK_00052 64818 3 Oral 0.33 protein_coding missense_variant MODERATE 416G>A Gly139Asp
M0137466 HPPEFDBK_00052 64915 3 Oral 0.33 protein_coding synonymous_variant LOW 513A>G Pro171Pro
M0137467 HPPEFDBK_00052 65833 3 Oral 0.33 protein_coding synonymous_variant LOW 1431A>G Ala477Ala
M0137468 HPPEFDBK_00052 65891 3 Oral 0.33 protein_coding missense_variant MODERATE 1489T>C Cys497Arg
M0137469 HPPEFDBK_00053 66528 3 Oral 0.33 protein_coding synonymous_variant LOW 637T>C Leu213Leu
M0137470 HPPEFDBK_00054 66724 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -205A>G None
M0137471 HPPEFDBK_00054 66785 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -144G>A None
M0137472 HPPEFDBK_00054 66840 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -89C>T None
M0137473 HPPEFDBK_00054 66872 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -57C>T None
M0137474 HPPEFDBK_00054 66877 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -52A>G None
M0137475 HPPEFDBK_00054 66907 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -22T>C None
M0137476 HPPEFDBK_00054 67058 3 Oral 0.33 protein_coding missense_variant MODERATE 130C>T Arg44Cys
M0137477 HPPEFDBK_00054 67071 3 Oral 0.33 protein_coding missense_variant MODERATE 143A>G His48Arg
M0137478 HPPEFDBK_00054 67161 3 Oral 0.33 protein_coding missense_variant MODERATE 233G>A Arg78Gln
M0137479 HPPEFDBK_00054 67428 3 Oral 0.33 protein_coding missense_variant MODERATE 500A>G Asp167Gly
M0137480 HPPEFDBK_00054 67487 3 Oral 0.33 protein_coding missense_variant MODERATE 559A>G Lys187Glu
M0137481 HPPEFDBK_00054 67517 3 Oral 0.33 protein_coding missense_variant MODERATE 589C>T Leu197Phe
M0137482 HPPEFDBK_00054 67549 3 Oral 0.33 protein_coding synonymous_variant LOW 621G>T Arg207Arg
M0137483 HPPEFDBK_00054 67770 3 Oral 0.33 protein_coding missense_variant MODERATE 842C>T Thr281Ile
M0137484 HPPEFDBK_00054 68018 3 Oral 0.33 protein_coding missense_variant MODERATE 1090G>A Glu364Lys
M0137485 HPPEFDBK_00054 68023 3 Oral 0.33 protein_coding synonymous_variant LOW 1095C>T Ile365Ile
M0137486 HPPEFDBK_00054 68174 3 Oral 0.33 protein_coding missense_variant MODERATE 1246T>G Leu416Val
M0137487 HPPEFDBK_00054 68194 3 Oral 0.33 protein_coding synonymous_variant LOW 1266T>C Gly422Gly
M0137488 HPPEFDBK_00054 68206 3 Oral 0.33 protein_coding synonymous_variant LOW 1278G>A Glu426Glu
M0137489 HPPEFDBK_00054 68304 3 Oral 0.33 protein_coding missense_variant MODERATE 1376T>C Leu459Pro
M0137490 HPPEFDBK_00054 68306 3 Oral 0.33 protein_coding missense_variant MODERATE 1378G>A Gly460Ser
M0137491 HPPEFDBK_00054 68359 3 Oral 0.33 protein_coding synonymous_variant LOW 1431T>C Ser477Ser
M0137492 HPPEFDBK_00055 68737 3 Oral 0.33 protein_coding missense_variant MODERATE 61A>G Thr21Ala
M0137493 HPPEFDBK_00055 69012 3 Oral 0.33 protein_coding synonymous_variant LOW 336G>T Leu112Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term