Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3370
  Reference Plasmid   MGYG000299016__MGYG000299016_39
  Reference Plasmid Size   6568
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0137534 NIAPDCPD_00003 2271 3 Oral 0.33 protein_coding missense_variant MODERATE 28T>G Phe10Val
M0137535 NIAPDCPD_00003 2285 6 Oral 0.67 protein_coding synonymous_variant LOW 42C>G Ala14Ala
M0137536 NIAPDCPD_00003 2325 5 Oral 0.56 protein_coding missense_variant MODERATE 82T>C Tyr28His
M0137537 NIAPDCPD_00003 2326 3 Oral 0.33 protein_coding missense_variant MODERATE 83A>T Tyr28Phe
M0137538 NIAPDCPD_00003 2453 3 Oral 0.33 protein_coding synonymous_variant LOW 210T>C Asn70Asn
M0137539 NIAPDCPD_00003 2495 3 Oral 0.33 protein_coding synonymous_variant LOW 252A>G Ala84Ala
M0137540 NIAPDCPD_00003 2600 4 Oral 0.44 protein_coding synonymous_variant LOW 357A>T Thr119Thr
M0137541 NIAPDCPD_00003 2688 4 Oral 0.44 protein_coding missense_variant MODERATE 445A>G Ile149Val
M0137542 NIAPDCPD_00003 2982 5 Oral 0.56 protein_coding missense_variant MODERATE 739A>G Thr247Ala
M0137543 NIAPDCPD_00003 3014 3 Oral 0.33 protein_coding synonymous_variant LOW 771T>C Ser257Ser
M0137544 NIAPDCPD_00003 3212 6 Oral 0.67 protein_coding synonymous_variant LOW 969C>T Asp323Asp
M0137545 NIAPDCPD_00004 3316 3 Oral 0.33 protein_coding synonymous_variant LOW 24T>C Ile8Ile
M0137546 NIAPDCPD_00004 3320 3 Oral 0.33 protein_coding synonymous_variant LOW 28T>C Leu10Leu
M0137547 NIAPDCPD_00004 3489 7 Oral 0.78 protein_coding missense_variant MODERATE 197G>A Gly66Glu
M0137548 NIAPDCPD_00004 3688 3 Oral 0.33 protein_coding synonymous_variant LOW 396A>G Lys132Lys
M0137549 NIAPDCPD_00004 3709 7 Oral 0.78 protein_coding missense_variant MODERATE 417A>T Arg139Ser
M0137550 NIAPDCPD_00004 3721 5 Oral 0.56 protein_coding synonymous_variant LOW 429A>T Thr143Thr
M0137551 NIAPDCPD_00004 3733 7 Oral 0.78 protein_coding synonymous_variant LOW 441A>G Leu147Leu
M0137552 NIAPDCPD_00004 3928 7 Oral 0.78 protein_coding synonymous_variant LOW 636G>A Gly212Gly
M0137553 NIAPDCPD_00004 3952 5 Oral 0.56 protein_coding synonymous_variant LOW 660T>C Arg220Arg
M0137554 NIAPDCPD_00004 3961 5 Oral 0.56 protein_coding synonymous_variant LOW 669C>T Asp223Asp
M0137555 NIAPDCPD_00004 3964 3 Oral 0.33 protein_coding synonymous_variant LOW 672A>C Ala224Ala
M0137556 NIAPDCPD_00004 4006 5 Oral 0.56 protein_coding synonymous_variant LOW 714A>T Ser238Ser
M0137557 NIAPDCPD_00004 4081 4 Oral 0.44 protein_coding missense_variant MODERATE 789G>T Glu263Asp
M0137558 NIAPDCPD_00004 4087 3 Oral 0.33 protein_coding synonymous_variant LOW 795T>A Thr265Thr
M0137559 NIAPDCPD_00004 4417 5 Oral 0.56 protein_coding synonymous_variant LOW 1125T>C Val375Val
M0137560 NIAPDCPD_00005 4567 5 Oral 0.56 protein_coding synonymous_variant LOW 111T>A Ser37Ser
M0137561 NIAPDCPD_00005 4658 5 Oral 0.56 protein_coding missense_variant MODERATE 202A>G Thr68Ala
M0137562 NIAPDCPD_00005 4687 5 Oral 0.56 protein_coding synonymous_variant LOW 231C>T Ala77Ala
M0137563 NIAPDCPD_00005 4715 3 Oral 0.33 protein_coding missense_variant MODERATE 259G>A Val87Ile
M0137564 NIAPDCPD_00005 4831 5 Oral 0.56 protein_coding synonymous_variant LOW 375T>C Asn125Asn
M0137565 NIAPDCPD_00005 4891 3 Oral 0.33 protein_coding synonymous_variant LOW 435G>A Gly145Gly
M0137566 NIAPDCPD_00005 4894 4 Oral 0.44 protein_coding synonymous_variant LOW 438T>C Ile146Ile
M0137567 NIAPDCPD_00005 4939 6 Oral 0.67 protein_coding synonymous_variant LOW 483A>G Ser161Ser
M0137568 NIAPDCPD_00005 4945 6 Oral 0.67 protein_coding synonymous_variant LOW 489A>G Glu163Glu
M0137569 NIAPDCPD_00005 5002 6 Oral 0.67 protein_coding synonymous_variant LOW 546G>A Lys182Lys
M0137570 NIAPDCPD_00005 5248 5 Oral 0.56 protein_coding synonymous_variant LOW 792C>T Ile264Ile
M0137571 NIAPDCPD_00005 5388 6 Oral 0.67 protein_coding missense_variant MODERATE 932A>G Asn311Ser
M0137572 NIAPDCPD_00005 5389 6 Oral 0.67 protein_coding synonymous_variant LOW 933T>C Asn311Asn
M0137573 NIAPDCPD_00005 5449 4 Oral 0.44 protein_coding synonymous_variant LOW 993A>G Val331Val
M0137574 NIAPDCPD_00005 5660 6 Oral 0.67 protein_coding missense_variant MODERATE 1204C>T Pro402Ser
M0137575 NIAPDCPD_00002 5932 5 Oral 0.56 protein_coding downstream_gene_variant MODIFIER *3731G>A None
M0137576 NIAPDCPD_00002 5962 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *3761G>A None
M0137577 NIAPDCPD_00002 5985 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *3784T>A None
M0137578 NIAPDCPD_00002 6056 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *3855A>G None
M0137579 NIAPDCPD_00002 6083 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *3882A>G None
M0137580 NIAPDCPD_00002 6244 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *4043T>C None
M0137581 NIAPDCPD_00002 6274 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *4073A>G None
M0137582 NIAPDCPD_00002 6338 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *4137A>C None
M0137583 NIAPDCPD_00002 6502 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *4301C>T None
M0137584 NIAPDCPD_00002 1769 5 Oral 0.56 protein_coding synonymous_variant LOW 1143T>C Gly381Gly
M0137585 NIAPDCPD_00002 1934 4 Oral 0.44 protein_coding synonymous_variant LOW 1308A>G Glu436Glu
M0137586 NIAPDCPD_00003 2288 3 Oral 0.33 protein_coding synonymous_variant LOW 45A>G Leu15Leu
M0137587 NIAPDCPD_00003 3149 3 Oral 0.33 protein_coding synonymous_variant LOW 906C>T Leu302Leu
M0137588 NIAPDCPD_00003 3203 3 Oral 0.33 protein_coding synonymous_variant LOW 960C>T Ala320Ala
M0137589 NIAPDCPD_00004 3448 4 Oral 0.44 protein_coding synonymous_variant LOW 156A>G Thr52Thr
M0137590 NIAPDCPD_00004 3520 3 Oral 0.33 protein_coding synonymous_variant LOW 228C>T Asp76Asp
M0137591 NIAPDCPD_00004 3571 5 Oral 0.56 protein_coding synonymous_variant LOW 279A>T Leu93Leu
M0137592 NIAPDCPD_00004 3577 5 Oral 0.56 protein_coding synonymous_variant LOW 285C>T Pro95Pro
M0137593 NIAPDCPD_00004 3742 3 Oral 0.33 protein_coding synonymous_variant LOW 450T>A Ser150Ser
M0137594 NIAPDCPD_00004 3745 3 Oral 0.33 protein_coding synonymous_variant LOW 453T>C Ala151Ala
M0137595 NIAPDCPD_00004 4066 4 Oral 0.44 protein_coding synonymous_variant LOW 774G>A Thr258Thr
M0137596 NIAPDCPD_00004 4135 3 Oral 0.33 protein_coding synonymous_variant LOW 843T>C Ser281Ser
M0137597 NIAPDCPD_00005 4798 3 Oral 0.33 protein_coding synonymous_variant LOW 342G>A Thr114Thr
M0137598 NIAPDCPD_00005 4813 3 Oral 0.33 protein_coding synonymous_variant LOW 357C>T Ala119Ala
M0137599 NIAPDCPD_00005 4814 3 Oral 0.33 protein_coding missense_variant MODERATE 358A>G Ile120Val
M0137600 NIAPDCPD_00005 4824 3 Oral 0.33 protein_coding missense_variant MODERATE 368C>T Ala123Val
M0137601 NIAPDCPD_00005 4849 5 Oral 0.56 protein_coding synonymous_variant LOW 393T>C Ile131Ile
M0137602 NIAPDCPD_00005 4981 3 Oral 0.33 protein_coding synonymous_variant LOW 525A>C Thr175Thr
M0137603 NIAPDCPD_00005 5071 3 Oral 0.33 protein_coding synonymous_variant LOW 615T>C Phe205Phe
M0137604 NIAPDCPD_00005 5339 5 Oral 0.56 protein_coding missense_variant MODERATE 883A>G Ile295Val
M0137605 NIAPDCPD_00001 321 4 Oral 0.44 protein_coding synonymous_variant LOW 276A>G Glu92Glu
M0137606 NIAPDCPD_00001 465 5 Oral 0.56 protein_coding synonymous_variant LOW 420G>A Ser140Ser
M0137607 NIAPDCPD_00001 483 4 Oral 0.44 protein_coding synonymous_variant LOW 438G>A Leu146Leu
M0137608 NIAPDCPD_00001 510 5 Oral 0.56 protein_coding synonymous_variant LOW 465C>T Phe155Phe
M0137609 NIAPDCPD_00002 654 4 Oral 0.44 protein_coding missense_variant MODERATE 28A>G Thr10Ala
M0137610 NIAPDCPD_00002 686 5 Oral 0.56 protein_coding synonymous_variant LOW 60T>A Thr20Thr
M0137611 NIAPDCPD_00002 1067 4 Oral 0.44 protein_coding synonymous_variant LOW 441C>T Ile147Ile
M0137612 NIAPDCPD_00002 1199 3 Oral 0.33 protein_coding synonymous_variant LOW 573A>T Thr191Thr
M0137613 NIAPDCPD_00002 1202 4 Oral 0.44 protein_coding synonymous_variant LOW 576A>T Ala192Ala
M0137614 NIAPDCPD_00002 1271 4 Oral 0.44 protein_coding synonymous_variant LOW 645A>G Lys215Lys
M0137615 NIAPDCPD_00002 1352 3 Oral 0.33 protein_coding synonymous_variant LOW 726A>G Glu242Glu
M0137616 NIAPDCPD_00002 1472 4 Oral 0.44 protein_coding synonymous_variant LOW 846T>C His282His
M0137617 NIAPDCPD_00002 1493 4 Oral 0.44 protein_coding synonymous_variant LOW 867C>T Ala289Ala
M0137618 NIAPDCPD_00002 1526 3 Oral 0.33 protein_coding synonymous_variant LOW 900T>C Asp300Asp
M0137619 NIAPDCPD_00002 1721 3 Oral 0.33 protein_coding synonymous_variant LOW 1095C>T Leu365Leu
M0137620 NIAPDCPD_00002 1742 3 Oral 0.33 protein_coding synonymous_variant LOW 1116G>A Gly372Gly
M0137621 NIAPDCPD_00004 3778 3 Oral 0.33 protein_coding synonymous_variant LOW 486C>T Ala162Ala
M0137622 NIAPDCPD_00004 3886 4 Oral 0.44 protein_coding synonymous_variant LOW 594A>C Val198Val
M0137623 NIAPDCPD_00005 5218 3 Oral 0.33 protein_coding synonymous_variant LOW 762A>G Glu254Glu
M0137624 NIAPDCPD_00005 5221 3 Oral 0.33 protein_coding synonymous_variant LOW 765T>G Pro255Pro
M0137625 NIAPDCPD_00005 5227 3 Oral 0.33 protein_coding synonymous_variant LOW 771A>G Gln257Gln
M0137626 NIAPDCPD_00001 552 3 Oral 0.33 protein_coding synonymous_variant LOW 507A>C Gly169Gly
M0137627 NIAPDCPD_00002 637 3 Oral 0.33 protein_coding missense_variant MODERATE 11T>A Ile4Lys
M0137628 NIAPDCPD_00002 655 3 Oral 0.33 protein_coding missense_variant MODERATE 29C>T Thr10Ile
M0137629 NIAPDCPD_00004 3385 3 Oral 0.33 protein_coding synonymous_variant LOW 93C>T Asn31Asn
M0137630 NIAPDCPD_00005 5407 3 Oral 0.33 protein_coding synonymous_variant LOW 951A>G Gly317Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
NIAPDCPD_00005 EFC70999.1|GH18 78.7 2.72e-266 1 454 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term