Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3371
  Reference Plasmid   MGYG000299026__MGYG000299026_221
  Reference Plasmid Size   23891
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0137631 JJHNHINL_00021 15085 3 Oral 0.33 protein_coding synonymous_variant LOW 207A>G Arg69Arg
M0137632 JJHNHINL_00021 15274 3 Oral 0.33 protein_coding synonymous_variant LOW 396C>T Tyr132Tyr
M0137633 JJHNHINL_00022 15419 3 Oral 0.33 protein_coding missense_variant MODERATE 23G>A Gly8Asp
M0137634 JJHNHINL_00022 15480 3 Oral 0.33 protein_coding synonymous_variant LOW 84T>C Gly28Gly
M0137635 JJHNHINL_00023 15654 3 Oral 0.33 protein_coding missense_variant MODERATE 25T>C Phe9Leu
M0137636 JJHNHINL_00023 15913 3 Oral 0.33 protein_coding missense_variant MODERATE 284T>C Phe95Ser
M0137637 JJHNHINL_00023 16178 3 Oral 0.33 protein_coding synonymous_variant LOW 549G>A Leu183Leu
M0137638 JJHNHINL_00023 16181 3 Oral 0.33 protein_coding synonymous_variant LOW 552T>C Tyr184Tyr
M0137639 JJHNHINL_00023 16251 3 Oral 0.33 protein_coding missense_variant MODERATE 622T>C Ser208Pro
M0137640 JJHNHINL_00024 16564 3 Oral 0.33 protein_coding synonymous_variant LOW 267T>A Val89Val
M0137641 JJHNHINL_00024 16597 3 Oral 0.33 protein_coding synonymous_variant LOW 300A>T Leu100Leu
M0137642 JJHNHINL_00024 16846 3 Oral 0.33 protein_coding synonymous_variant LOW 549T>C Tyr183Tyr
M0137643 JJHNHINL_00024 16855 3 Oral 0.33 protein_coding synonymous_variant LOW 558A>G Lys186Lys
M0137644 JJHNHINL_00024 16864 3 Oral 0.33 protein_coding synonymous_variant LOW 567T>C Arg189Arg
M0137645 JJHNHINL_00024 16870 3 Oral 0.33 protein_coding synonymous_variant LOW 573G>T Gly191Gly
M0137646 JJHNHINL_00024 16900 3 Oral 0.33 protein_coding synonymous_variant LOW 603T>A Ala201Ala
M0137647 JJHNHINL_00024 16924 3 Oral 0.33 protein_coding synonymous_variant LOW 627T>A Gly209Gly
M0137648 JJHNHINL_00024 16927 3 Oral 0.33 protein_coding synonymous_variant LOW 630T>A Ser210Ser
M0137649 JJHNHINL_00024 16933 3 Oral 0.33 protein_coding synonymous_variant LOW 636A>G Lys212Lys
M0137650 JJHNHINL_00024 16954 3 Oral 0.33 protein_coding synonymous_variant LOW 657T>C Pro219Pro
M0137651 JJHNHINL_00024 16963 3 Oral 0.33 protein_coding synonymous_variant LOW 666G>T Arg222Arg
M0137652 JJHNHINL_00024 16969 3 Oral 0.33 protein_coding synonymous_variant LOW 672C>T His224His
M0137653 JJHNHINL_00024 16972 3 Oral 0.33 protein_coding synonymous_variant LOW 675T>A Ser225Ser
M0137654 JJHNHINL_00024 17812 3 Oral 0.33 protein_coding synonymous_variant LOW 1515T>C Arg505Arg
M0137655 JJHNHINL_00016 10421 3 Oral 0.33 protein_coding synonymous_variant LOW 174T>A Gly58Gly
M0137656 JJHNHINL_00016 10427 3 Oral 0.33 protein_coding synonymous_variant LOW 180A>T Thr60Thr
M0137657 JJHNHINL_00016 10430 3 Oral 0.33 protein_coding synonymous_variant LOW 183C>T Leu61Leu
M0137658 JJHNHINL_00016 10436 3 Oral 0.33 protein_coding synonymous_variant LOW 189A>G Leu63Leu
M0137659 JJHNHINL_00016 10457 3 Oral 0.33 protein_coding synonymous_variant LOW 210T>C Cys70Cys
M0137660 JJHNHINL_00016 10469 3 Oral 0.33 protein_coding synonymous_variant LOW 222A>T Ile74Ile
M0137661 JJHNHINL_00016 10511 3 Oral 0.33 protein_coding synonymous_variant LOW 264C>T Ile88Ile
M0137662 JJHNHINL_00016 10523 3 Oral 0.33 protein_coding synonymous_variant LOW 276A>T Ala92Ala
M0137663 JJHNHINL_00016 10526 3 Oral 0.33 protein_coding synonymous_variant LOW 279A>T Ile93Ile
M0137664 JJHNHINL_00016 10532 3 Oral 0.33 protein_coding synonymous_variant LOW 285C>T Ile95Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
JJHNHINL_00027 ATV39431.1|GH0 99.2 1.13e-267 1 368 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term