Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3373
  Reference Plasmid   MGYG000299029__MGYG000299029_199
  Reference Plasmid Size   2703
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0137672 DAAOEFFH_00001 166 3 Oral 0.60 protein_coding synonymous_variant LOW 108C>T Asn36Asn
M0137673 DAAOEFFH_00002 690 3 Oral 0.60 protein_coding synonymous_variant LOW 102G>A Gln34Gln
M0137674 DAAOEFFH_00002 705 3 Oral 0.60 protein_coding synonymous_variant LOW 117A>C Leu39Leu
M0137675 DAAOEFFH_00002 717 4 Oral 0.80 protein_coding synonymous_variant LOW 129A>C Thr43Thr
M0137676 DAAOEFFH_00002 867 4 Oral 0.80 protein_coding synonymous_variant LOW 279T>C Tyr93Tyr
M0137677 DAAOEFFH_00002 954 5 Oral 1.00 protein_coding synonymous_variant LOW 366C>T Ala122Ala
M0137678 DAAOEFFH_00002 1206 4 Oral 0.80 protein_coding synonymous_variant LOW 618T>C Asp206Asp
M0137679 DAAOEFFH_00002 1256 5 Oral 1.00 protein_coding missense_variant MODERATE 668A>G Asn223Ser
M0137680 DAAOEFFH_00002 1290 5 Oral 1.00 protein_coding synonymous_variant LOW 702C>G Leu234Leu
M0137681 DAAOEFFH_00002 1500 5 Oral 1.00 protein_coding synonymous_variant LOW 912C>A Thr304Thr
M0137682 DAAOEFFH_00002 1692 4 Oral 0.80 protein_coding synonymous_variant LOW 1104T>C Ile368Ile
M0137683 DAAOEFFH_00002 1882 4 Oral 0.80 protein_coding synonymous_variant LOW 1294T>C Leu432Leu
M0137684 DAAOEFFH_00002 1899 3 Oral 0.60 protein_coding synonymous_variant LOW 1311C>T Ile437Ile
M0137685 DAAOEFFH_00002 2100 5 Oral 1.00 protein_coding synonymous_variant LOW 1512A>G Lys504Lys
M0137686 DAAOEFFH_00002 2226 4 Oral 0.80 protein_coding synonymous_variant LOW 1638T>C Pro546Pro
M0137687 DAAOEFFH_00002 2244 4 Oral 0.80 protein_coding synonymous_variant LOW 1656C>T Gly552Gly
M0137688 DAAOEFFH_00002 2331 5 Oral 1.00 protein_coding synonymous_variant LOW 1743A>C Gly581Gly
M0137689 DAAOEFFH_00002 1714 3 Oral 0.60 protein_coding missense_variant MODERATE 1126A>C Met376Leu
M0137690 DAAOEFFH_00002 2385 4 Oral 0.80 protein_coding synonymous_variant LOW 1797T>C Phe599Phe
M0137691 DAAOEFFH_00001 128 3 Oral 0.60 protein_coding missense_variant MODERATE 70A>G Lys24Glu
M0137692 DAAOEFFH_00001 170 3 Oral 0.60 protein_coding synonymous_variant LOW 112C>T Leu38Leu
M0137693 DAAOEFFH_00002 1560 3 Oral 0.60 protein_coding synonymous_variant LOW 972G>A Ala324Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term